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Results from Phase I Clinical Trial with Intraspinal Injection of Neural Stem Cells in Amyotrophic Lateral Sclerosis: A Long-Term Outcome.

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Title: Results from Phase I Clinical Trial with Intraspinal Injection of Neural Stem Cells in Amyotrophic Lateral Sclerosis: A Long-Term Outcome.
Authors: Mazzini L; Eastern Piedmont University, 'Maggiore della Carità' Hospital, Dipartimento di Neurologia, Novara., Gelati M; Laboratorio Cellule Staminali, Cell Factory e Biobanca, Terni Hospital, Italy.; Fondazione IRCCS Casa Sollievo della Sofferenza, Advanced Therapies Production Unit, San Giovanni Rotondo, Foggia, Italy., Profico DC; Fondazione IRCCS Casa Sollievo della Sofferenza, Advanced Therapies Production Unit, San Giovanni Rotondo, Foggia, Italy., Sorarù G; Department of Neuroscience, University of Padua, Padua, Italy., Ferrari D; Biotechnology and Bioscience Department Bicocca University, Milan, Italy., Copetti M; Fondazione IRCCS Casa Sollievo della Sofferenza, Biostatistic Unit, San Giovanni Rotondo, Foggia, Italy., Muzi G; Laboratorio Cellule Staminali, Cell Factory e Biobanca, Terni Hospital, Italy., Ricciolini C; Laboratorio Cellule Staminali, Cell Factory e Biobanca, Terni Hospital, Italy., Carletti S; Department of Neurosurgery and Neuroscience, 'Santa Maria' Hospital, Terni, Italy., Giorgi C; Department of Neurosurgery and Neuroscience, 'Santa Maria' Hospital, Terni, Italy., Spera C; Department of Neurosurgery and Neuroscience, 'Santa Maria' Hospital, Terni, Italy., Frondizi D; Department of Neurosurgery and Neuroscience, 'Santa Maria' Hospital, Terni, Italy., Masiero S; Department of Neuroscience, University of Padua, Padua, Italy., Stecco A; Department of Diagnostic and Interventional Radiology, 'Eastern Piedmont' University, 'Maggiore della Carità' Hospital, Novara., Cisari C; Department of Physical Therapy, 'Eastern Piedmont' University, 'Maggiore della Carità' Hospital, Novara., Bersano E; Eastern Piedmont University, 'Maggiore della Carità' Hospital, Dipartimento di Neurologia, Novara., De Marchi F; Eastern Piedmont University, 'Maggiore della Carità' Hospital, Dipartimento di Neurologia, Novara., Sarnelli MF; Eastern Piedmont University, 'Maggiore della Carità' Hospital, Dipartimento di Neurologia, Novara., Querin G; Department of Neuroscience, University of Padua, Padua, Italy., Cantello R; Eastern Piedmont University, 'Maggiore della Carità' Hospital, Dipartimento di Neurologia, Novara., Petruzzelli F; Fondazione IRCCS Casa Sollievo della Sofferenza, Obstetrics and Gynaecology Department, San Giovanni Rotondo, Foggia, Italy., Maglione A; Fondazione IRCCS Casa Sollievo della Sofferenza, Obstetrics and Gynaecology Department, San Giovanni Rotondo, Foggia, Italy., Zalfa C; Biotechnology and Bioscience Department Bicocca University, Milan, Italy., Binda E; Fondazione IRCCS Casa Sollievo della Sofferenza, Cancer Stem Cells Unit, San Giovanni Rotondo, Foggia, Italy., Visioli A; StemGen SpA, Milan, Italy., Trombetta D; Fondazione IRCCS Casa Sollievo della Sofferenza, Department of Oncology, San Giovanni Rotondo, Foggia, Italy., Torres B; Fondazione IRCCS Casa Sollievo della Sofferenza, Cytogenetics Unit, San Giovanni Rotondo, Foggia, Italy., Bernardini L; Fondazione IRCCS Casa Sollievo della Sofferenza, Cytogenetics Unit, San Giovanni Rotondo, Foggia, Italy., Gaiani A; Department of Neuroscience, University of Padua, Padua, Italy., Massara M; Eastern Piedmont University, 'Maggiore della Carità' Hospital, Dipartimento di Neurologia, Novara., Paolucci S; Eastern Piedmont University, 'Maggiore della Carità' Hospital, Dipartimento di Neurologia, Novara., Boulis NM; Department of Neurosurgery, Emory University, Atlanta, USA., Vescovi AL; Laboratorio Cellule Staminali, Cell Factory e Biobanca, Terni Hospital, Italy.; Fondazione IRCCS Casa Sollievo della Sofferenza, Advanced Therapies Production Unit, San Giovanni Rotondo, Foggia, Italy.; Biotechnology and Bioscience Department Bicocca University, Milan, Italy.
Corporate Authors: ALS-NSCs Trial Study Group
Source: Stem cells translational medicine [Stem Cells Transl Med] 2019 Sep; Vol. 8 (9), pp. 887-897. Date of Electronic Publication: 2019 May 18.
Publication Type: Clinical Trial, Phase I; Journal Article
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 101578022 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2157-6580 (Electronic) Linking ISSN: 21576564 NLM ISO Abbreviation: Stem Cells Transl Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Results from Phase I Clinical Trial with Intraspinal Injection of Neural Stem Cells in Amyotrophic Lateral Sclerosis: A Long-Term Outcome.
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  Data: <searchLink fieldCode="AU" term="%22Mazzini+L%22">Mazzini L</searchLink>; Eastern Piedmont University, 'Maggiore della Carità' Hospital, Dipartimento di Neurologia, Novara.<br /><searchLink fieldCode="AU" term="%22Gelati+M%22">Gelati M</searchLink>; Laboratorio Cellule Staminali, Cell Factory e Biobanca, Terni Hospital, Italy.; Fondazione IRCCS Casa Sollievo della Sofferenza, Advanced Therapies Production Unit, San Giovanni Rotondo, Foggia, Italy.<br /><searchLink fieldCode="AU" term="%22Profico+DC%22">Profico DC</searchLink>; Fondazione IRCCS Casa Sollievo della Sofferenza, Advanced Therapies Production Unit, San Giovanni Rotondo, Foggia, Italy.<br /><searchLink fieldCode="AU" term="%22Sorarù+G%22">Sorarù G</searchLink>; Department of Neuroscience, University of Padua, Padua, Italy.<br /><searchLink fieldCode="AU" term="%22Ferrari+D%22">Ferrari D</searchLink>; Biotechnology and Bioscience Department Bicocca University, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Copetti+M%22">Copetti M</searchLink>; Fondazione IRCCS Casa Sollievo della Sofferenza, Biostatistic Unit, San Giovanni Rotondo, Foggia, Italy.<br /><searchLink fieldCode="AU" term="%22Muzi+G%22">Muzi G</searchLink>; Laboratorio Cellule Staminali, Cell Factory e Biobanca, Terni Hospital, Italy.<br /><searchLink fieldCode="AU" term="%22Ricciolini+C%22">Ricciolini C</searchLink>; Laboratorio Cellule Staminali, Cell Factory e Biobanca, Terni Hospital, Italy.<br /><searchLink fieldCode="AU" term="%22Carletti+S%22">Carletti S</searchLink>; Department of Neurosurgery and Neuroscience, 'Santa Maria' Hospital, Terni, Italy.<br /><searchLink fieldCode="AU" term="%22Giorgi+C%22">Giorgi C</searchLink>; Department of Neurosurgery and Neuroscience, 'Santa Maria' Hospital, Terni, Italy.<br /><searchLink fieldCode="AU" term="%22Spera+C%22">Spera C</searchLink>; Department of Neurosurgery and Neuroscience, 'Santa Maria' Hospital, Terni, Italy.<br /><searchLink fieldCode="AU" term="%22Frondizi+D%22">Frondizi D</searchLink>; Department of Neurosurgery and Neuroscience, 'Santa Maria' Hospital, Terni, Italy.<br /><searchLink fieldCode="AU" term="%22Masiero+S%22">Masiero S</searchLink>; Department of Neuroscience, University of Padua, Padua, Italy.<br /><searchLink fieldCode="AU" term="%22Stecco+A%22">Stecco A</searchLink>; Department of Diagnostic and Interventional Radiology, 'Eastern Piedmont' University, 'Maggiore della Carità' Hospital, Novara.<br /><searchLink fieldCode="AU" term="%22Cisari+C%22">Cisari C</searchLink>; Department of Physical Therapy, 'Eastern Piedmont' University, 'Maggiore della Carità' Hospital, Novara.<br /><searchLink fieldCode="AU" term="%22Bersano+E%22">Bersano E</searchLink>; Eastern Piedmont University, 'Maggiore della Carità' Hospital, Dipartimento di Neurologia, Novara.<br /><searchLink fieldCode="AU" term="%22De+Marchi+F%22">De Marchi F</searchLink>; Eastern Piedmont University, 'Maggiore della Carità' Hospital, Dipartimento di Neurologia, Novara.<br /><searchLink fieldCode="AU" term="%22Sarnelli+MF%22">Sarnelli MF</searchLink>; Eastern Piedmont University, 'Maggiore della Carità' Hospital, Dipartimento di Neurologia, Novara.<br /><searchLink fieldCode="AU" term="%22Querin+G%22">Querin G</searchLink>; Department of Neuroscience, University of Padua, Padua, Italy.<br /><searchLink fieldCode="AU" term="%22Cantello+R%22">Cantello R</searchLink>; Eastern Piedmont University, 'Maggiore della Carità' Hospital, Dipartimento di Neurologia, Novara.<br /><searchLink fieldCode="AU" term="%22Petruzzelli+F%22">Petruzzelli F</searchLink>; Fondazione IRCCS Casa Sollievo della Sofferenza, Obstetrics and Gynaecology Department, San Giovanni Rotondo, Foggia, Italy.<br /><searchLink fieldCode="AU" term="%22Maglione+A%22">Maglione A</searchLink>; Fondazione IRCCS Casa Sollievo della Sofferenza, Obstetrics and Gynaecology Department, San Giovanni Rotondo, Foggia, Italy.<br /><searchLink fieldCode="AU" term="%22Zalfa+C%22">Zalfa C</searchLink>; Biotechnology and Bioscience Department Bicocca University, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Binda+E%22">Binda E</searchLink>; Fondazione IRCCS Casa Sollievo della Sofferenza, Cancer Stem Cells Unit, San Giovanni Rotondo, Foggia, Italy.<br /><searchLink fieldCode="AU" term="%22Visioli+A%22">Visioli A</searchLink>; StemGen SpA, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Trombetta+D%22">Trombetta D</searchLink>; Fondazione IRCCS Casa Sollievo della Sofferenza, Department of Oncology, San Giovanni Rotondo, Foggia, Italy.<br /><searchLink fieldCode="AU" term="%22Torres+B%22">Torres B</searchLink>; Fondazione IRCCS Casa Sollievo della Sofferenza, Cytogenetics Unit, San Giovanni Rotondo, Foggia, Italy.<br /><searchLink fieldCode="AU" term="%22Bernardini+L%22">Bernardini L</searchLink>; Fondazione IRCCS Casa Sollievo della Sofferenza, Cytogenetics Unit, San Giovanni Rotondo, Foggia, Italy.<br /><searchLink fieldCode="AU" term="%22Gaiani+A%22">Gaiani A</searchLink>; Department of Neuroscience, University of Padua, Padua, Italy.<br /><searchLink fieldCode="AU" term="%22Massara+M%22">Massara M</searchLink>; Eastern Piedmont University, 'Maggiore della Carità' Hospital, Dipartimento di Neurologia, Novara.<br /><searchLink fieldCode="AU" term="%22Paolucci+S%22">Paolucci S</searchLink>; Eastern Piedmont University, 'Maggiore della Carità' Hospital, Dipartimento di Neurologia, Novara.<br /><searchLink fieldCode="AU" term="%22Boulis+NM%22">Boulis NM</searchLink>; Department of Neurosurgery, Emory University, Atlanta, USA.<br /><searchLink fieldCode="AU" term="%22Vescovi+AL%22">Vescovi AL</searchLink>; Laboratorio Cellule Staminali, Cell Factory e Biobanca, Terni Hospital, Italy.; Fondazione IRCCS Casa Sollievo della Sofferenza, Advanced Therapies Production Unit, San Giovanni Rotondo, Foggia, Italy.; Biotechnology and Bioscience Department Bicocca University, Milan, Italy.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Oxford+University+Press%22">Oxford University Press </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101578022 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2157-6580 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2221576564%22">21576564 </searchLink><i>NLM ISO Abbreviation: </i>Stem Cells Transl Med <i>Subsets: </i>MEDLINE
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