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Structural insights into dehydratase substrate selection for the borrelidin and fluvirucin polyketide synthases.

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Title: Structural insights into dehydratase substrate selection for the borrelidin and fluvirucin polyketide synthases.
Authors: Barajas JF; Department of Energy Agile BioFoundry, Emeryville, CA, 94608, USA.; Biological Systems and Engineering Division, Lawrence Berkeley National Laboratory, Berkeley, CA, 94720, USA., McAndrew RP; Joint BioEnergy Institute, 5885 Hollis St. 4th Floor, Emeryville, CA, 94608, USA.; Molecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA, 94720, USA., Thompson MG; Biological Systems and Engineering Division, Lawrence Berkeley National Laboratory, Berkeley, CA, 94720, USA.; Joint BioEnergy Institute, 5885 Hollis St. 4th Floor, Emeryville, CA, 94608, USA., Backman TWH; Biological Systems and Engineering Division, Lawrence Berkeley National Laboratory, Berkeley, CA, 94720, USA.; Joint BioEnergy Institute, 5885 Hollis St. 4th Floor, Emeryville, CA, 94608, USA.; Department of Bioengineering, University of California, Berkeley, CA, 94720, USA.; QB3 Institute, University of California, Berkeley, Emeryville, CA, 94608, USA., Pang B; Biological Systems and Engineering Division, Lawrence Berkeley National Laboratory, Berkeley, CA, 94720, USA.; Joint BioEnergy Institute, 5885 Hollis St. 4th Floor, Emeryville, CA, 94608, USA.; QB3 Institute, University of California, Berkeley, Emeryville, CA, 94608, USA., de Rond T; Biological Systems and Engineering Division, Lawrence Berkeley National Laboratory, Berkeley, CA, 94720, USA.; Joint BioEnergy Institute, 5885 Hollis St. 4th Floor, Emeryville, CA, 94608, USA., Pereira JH; Joint BioEnergy Institute, 5885 Hollis St. 4th Floor, Emeryville, CA, 94608, USA.; Molecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA, 94720, USA., Benites VT; Department of Energy Agile BioFoundry, Emeryville, CA, 94608, USA.; Biological Systems and Engineering Division, Lawrence Berkeley National Laboratory, Berkeley, CA, 94720, USA.; Joint BioEnergy Institute, 5885 Hollis St. 4th Floor, Emeryville, CA, 94608, USA., Martín HG; Department of Energy Agile BioFoundry, Emeryville, CA, 94608, USA.; Biological Systems and Engineering Division, Lawrence Berkeley National Laboratory, Berkeley, CA, 94720, USA.; Joint BioEnergy Institute, 5885 Hollis St. 4th Floor, Emeryville, CA, 94608, USA., Baidoo EEK; Department of Energy Agile BioFoundry, Emeryville, CA, 94608, USA.; Biological Systems and Engineering Division, Lawrence Berkeley National Laboratory, Berkeley, CA, 94720, USA.; Joint BioEnergy Institute, 5885 Hollis St. 4th Floor, Emeryville, CA, 94608, USA., Hillson NJ; Department of Energy Agile BioFoundry, Emeryville, CA, 94608, USA.; Biological Systems and Engineering Division, Lawrence Berkeley National Laboratory, Berkeley, CA, 94720, USA.; Joint BioEnergy Institute, 5885 Hollis St. 4th Floor, Emeryville, CA, 94608, USA., Adams PD; Biological Systems and Engineering Division, Lawrence Berkeley National Laboratory, Berkeley, CA, 94720, USA.; Joint BioEnergy Institute, 5885 Hollis St. 4th Floor, Emeryville, CA, 94608, USA.; Molecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA, 94720, USA.; Department of Bioengineering, University of California, Berkeley, CA, 94720, USA., Keasling JD; Biological Systems and Engineering Division, Lawrence Berkeley National Laboratory, Berkeley, CA, 94720, USA. jdkeasling@lbl.gov.; Joint BioEnergy Institute, 5885 Hollis St. 4th Floor, Emeryville, CA, 94608, USA. jdkeasling@lbl.gov.; Department of Bioengineering, University of California, Berkeley, CA, 94720, USA. jdkeasling@lbl.gov.; QB3 Institute, University of California, Berkeley, Emeryville, CA, 94608, USA. jdkeasling@lbl.gov.; Department of Chemical and Biomolecular Engineering, University of California, Berkeley, Berkeley, CA, 94720, USA. jdkeasling@lbl.gov.; Novo Nordisk Foundation Center for Biosustainability, Technical University Denmark, 2970, Horsholm, Denmark. jdkeasling@lbl.gov.; Synthetic Biochemistry Center, Institute for Synthetic Biology, Shenzhen Institutes for Advanced Technologies, Shenzhen, China. jdkeasling@lbl.gov.
Source: Journal of industrial microbiology & biotechnology [J Ind Microbiol Biotechnol] 2019 Aug; Vol. 46 (8), pp. 1225-1235. Date of Electronic Publication: 2019 May 21.
Publication Type: Journal Article
Journal Info: Publisher: Oxford University Press Country of Publication: Germany NLM ID: 9705544 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5535 (Electronic) Linking ISSN: 13675435 NLM ISO Abbreviation: J Ind Microbiol Biotechnol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Structural insights into dehydratase substrate selection for the borrelidin and fluvirucin polyketide synthases.
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  Data: <searchLink fieldCode="AU" term="%22Barajas+JF%22">Barajas JF</searchLink>; Department of Energy Agile BioFoundry, Emeryville, CA, 94608, USA.; Biological Systems and Engineering Division, Lawrence Berkeley National Laboratory, Berkeley, CA, 94720, USA.<br /><searchLink fieldCode="AU" term="%22McAndrew+RP%22">McAndrew RP</searchLink>; Joint BioEnergy Institute, 5885 Hollis St. 4th Floor, Emeryville, CA, 94608, USA.; Molecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA, 94720, USA.<br /><searchLink fieldCode="AU" term="%22Thompson+MG%22">Thompson MG</searchLink>; Biological Systems and Engineering Division, Lawrence Berkeley National Laboratory, Berkeley, CA, 94720, USA.; Joint BioEnergy Institute, 5885 Hollis St. 4th Floor, Emeryville, CA, 94608, USA.<br /><searchLink fieldCode="AU" term="%22Backman+TWH%22">Backman TWH</searchLink>; Biological Systems and Engineering Division, Lawrence Berkeley National Laboratory, Berkeley, CA, 94720, USA.; Joint BioEnergy Institute, 5885 Hollis St. 4th Floor, Emeryville, CA, 94608, USA.; Department of Bioengineering, University of California, Berkeley, CA, 94720, USA.; QB3 Institute, University of California, Berkeley, Emeryville, CA, 94608, USA.<br /><searchLink fieldCode="AU" term="%22Pang+B%22">Pang B</searchLink>; Biological Systems and Engineering Division, Lawrence Berkeley National Laboratory, Berkeley, CA, 94720, USA.; Joint BioEnergy Institute, 5885 Hollis St. 4th Floor, Emeryville, CA, 94608, USA.; QB3 Institute, University of California, Berkeley, Emeryville, CA, 94608, USA.<br /><searchLink fieldCode="AU" term="%22de+Rond+T%22">de Rond T</searchLink>; Biological Systems and Engineering Division, Lawrence Berkeley National Laboratory, Berkeley, CA, 94720, USA.; Joint BioEnergy Institute, 5885 Hollis St. 4th Floor, Emeryville, CA, 94608, USA.<br /><searchLink fieldCode="AU" term="%22Pereira+JH%22">Pereira JH</searchLink>; Joint BioEnergy Institute, 5885 Hollis St. 4th Floor, Emeryville, CA, 94608, USA.; Molecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA, 94720, USA.<br /><searchLink fieldCode="AU" term="%22Benites+VT%22">Benites VT</searchLink>; Department of Energy Agile BioFoundry, Emeryville, CA, 94608, USA.; Biological Systems and Engineering Division, Lawrence Berkeley National Laboratory, Berkeley, CA, 94720, USA.; Joint BioEnergy Institute, 5885 Hollis St. 4th Floor, Emeryville, CA, 94608, USA.<br /><searchLink fieldCode="AU" term="%22Martín+HG%22">Martín HG</searchLink>; Department of Energy Agile BioFoundry, Emeryville, CA, 94608, USA.; Biological Systems and Engineering Division, Lawrence Berkeley National Laboratory, Berkeley, CA, 94720, USA.; Joint BioEnergy Institute, 5885 Hollis St. 4th Floor, Emeryville, CA, 94608, USA.<br /><searchLink fieldCode="AU" term="%22Baidoo+EEK%22">Baidoo EEK</searchLink>; Department of Energy Agile BioFoundry, Emeryville, CA, 94608, USA.; Biological Systems and Engineering Division, Lawrence Berkeley National Laboratory, Berkeley, CA, 94720, USA.; Joint BioEnergy Institute, 5885 Hollis St. 4th Floor, Emeryville, CA, 94608, USA.<br /><searchLink fieldCode="AU" term="%22Hillson+NJ%22">Hillson NJ</searchLink>; Department of Energy Agile BioFoundry, Emeryville, CA, 94608, USA.; Biological Systems and Engineering Division, Lawrence Berkeley National Laboratory, Berkeley, CA, 94720, USA.; Joint BioEnergy Institute, 5885 Hollis St. 4th Floor, Emeryville, CA, 94608, USA.<br /><searchLink fieldCode="AU" term="%22Adams+PD%22">Adams PD</searchLink>; Biological Systems and Engineering Division, Lawrence Berkeley National Laboratory, Berkeley, CA, 94720, USA.; Joint BioEnergy Institute, 5885 Hollis St. 4th Floor, Emeryville, CA, 94608, USA.; Molecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA, 94720, USA.; Department of Bioengineering, University of California, Berkeley, CA, 94720, USA.<br /><searchLink fieldCode="AU" term="%22Keasling+JD%22">Keasling JD</searchLink>; Biological Systems and Engineering Division, Lawrence Berkeley National Laboratory, Berkeley, CA, 94720, USA. jdkeasling@lbl.gov.; Joint BioEnergy Institute, 5885 Hollis St. 4th Floor, Emeryville, CA, 94608, USA. jdkeasling@lbl.gov.; Department of Bioengineering, University of California, Berkeley, CA, 94720, USA. jdkeasling@lbl.gov.; QB3 Institute, University of California, Berkeley, Emeryville, CA, 94608, USA. jdkeasling@lbl.gov.; Department of Chemical and Biomolecular Engineering, University of California, Berkeley, Berkeley, CA, 94720, USA. jdkeasling@lbl.gov.; Novo Nordisk Foundation Center for Biosustainability, Technical University Denmark, 2970, Horsholm, Denmark. jdkeasling@lbl.gov.; Synthetic Biochemistry Center, Institute for Synthetic Biology, Shenzhen Institutes for Advanced Technologies, Shenzhen, China. jdkeasling@lbl.gov.
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