Senescent cells evade immune clearance via HLA-E-mediated NK and CD8+ T cell inhibition.
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| Title: | Senescent cells evade immune clearance via HLA-E-mediated NK and CD8+ T cell inhibition. |
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| Authors: | Pereira BI; Division of Infection and Immunity, University College London, London, WC1E 6JF, UK., Devine OP; Division of Infection and Immunity, University College London, London, WC1E 6JF, UK., Vukmanovic-Stejic M; Division of Infection and Immunity, University College London, London, WC1E 6JF, UK., Chambers ES; Division of Infection and Immunity, University College London, London, WC1E 6JF, UK., Subramanian P; Division of Infection and Immunity, University College London, London, WC1E 6JF, UK., Patel N; Division of Infection and Immunity, University College London, London, WC1E 6JF, UK., Virasami A; Institute of Histopathology, Great Ormond Street Hospital for Children, University College London, London, WC1N 3JH, UK., Sebire NJ; Institute of Histopathology, Great Ormond Street Hospital for Children, University College London, London, WC1N 3JH, UK., Kinsler V; Paediatric Dermatology Department, Great Ormond Street Hospital for Children, University College London, London, WC1N 3JH, UK., Valdovinos A; Buck Institute for Research on Aging, 8001 Redwood Blvd, Novato, CA, 94945, USA., LeSaux CJ; Buck Institute for Research on Aging, 8001 Redwood Blvd, Novato, CA, 94945, USA., Passos JF; Institute for Cell and Molecular Biosciences & Newcastle University Institute for Ageing, Newcastle upon Tyne, NE1 7RU, UK.; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, 55905, MN, USA., Antoniou A; Department of Applied Sciences, Faculty of Health and Life Sciences, Northumbria University, Newcastle Upon Tyne, NE1 8ST, UK., Rustin MHA; Division of Infection and Immunity, University College London, London, WC1E 6JF, UK., Campisi J; Buck Institute for Research on Aging, 8001 Redwood Blvd, Novato, CA, 94945, USA.; Lawrence Berkeley National Laboratory, 1 Cyclotron Rd, Berkeley, CA, 94720, USA., Akbar AN; Division of Infection and Immunity, University College London, London, WC1E 6JF, UK. a.akbar@ucl.ac.uk. |
| Source: | Nature communications [Nat Commun] 2019 Jun 03; Vol. 10 (1), pp. 2387. Date of Electronic Publication: 2019 Jun 03. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-1723 |
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| DOI: | 10.1038/s41467-019-10335-5 |
