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Senescent cells evade immune clearance via HLA-E-mediated NK and CD8+ T cell inhibition.

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Title: Senescent cells evade immune clearance via HLA-E-mediated NK and CD8+ T cell inhibition.
Authors: Pereira BI; Division of Infection and Immunity, University College London, London, WC1E 6JF, UK., Devine OP; Division of Infection and Immunity, University College London, London, WC1E 6JF, UK., Vukmanovic-Stejic M; Division of Infection and Immunity, University College London, London, WC1E 6JF, UK., Chambers ES; Division of Infection and Immunity, University College London, London, WC1E 6JF, UK., Subramanian P; Division of Infection and Immunity, University College London, London, WC1E 6JF, UK., Patel N; Division of Infection and Immunity, University College London, London, WC1E 6JF, UK., Virasami A; Institute of Histopathology, Great Ormond Street Hospital for Children, University College London, London, WC1N 3JH, UK., Sebire NJ; Institute of Histopathology, Great Ormond Street Hospital for Children, University College London, London, WC1N 3JH, UK., Kinsler V; Paediatric Dermatology Department, Great Ormond Street Hospital for Children, University College London, London, WC1N 3JH, UK., Valdovinos A; Buck Institute for Research on Aging, 8001 Redwood Blvd, Novato, CA, 94945, USA., LeSaux CJ; Buck Institute for Research on Aging, 8001 Redwood Blvd, Novato, CA, 94945, USA., Passos JF; Institute for Cell and Molecular Biosciences & Newcastle University Institute for Ageing, Newcastle upon Tyne, NE1 7RU, UK.; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, 55905, MN, USA., Antoniou A; Department of Applied Sciences, Faculty of Health and Life Sciences, Northumbria University, Newcastle Upon Tyne, NE1 8ST, UK., Rustin MHA; Division of Infection and Immunity, University College London, London, WC1E 6JF, UK., Campisi J; Buck Institute for Research on Aging, 8001 Redwood Blvd, Novato, CA, 94945, USA.; Lawrence Berkeley National Laboratory, 1 Cyclotron Rd, Berkeley, CA, 94720, USA., Akbar AN; Division of Infection and Immunity, University College London, London, WC1E 6JF, UK. a.akbar@ucl.ac.uk.
Source: Nature communications [Nat Commun] 2019 Jun 03; Vol. 10 (1), pp. 2387. Date of Electronic Publication: 2019 Jun 03.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Senescent cells evade immune clearance via HLA-E-mediated NK and CD8<superscript>+</superscript> T cell inhibition.
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  Data: <searchLink fieldCode="AU" term="%22Pereira+BI%22">Pereira BI</searchLink>; Division of Infection and Immunity, University College London, London, WC1E 6JF, UK.<br /><searchLink fieldCode="AU" term="%22Devine+OP%22">Devine OP</searchLink>; Division of Infection and Immunity, University College London, London, WC1E 6JF, UK.<br /><searchLink fieldCode="AU" term="%22Vukmanovic-Stejic+M%22">Vukmanovic-Stejic M</searchLink>; Division of Infection and Immunity, University College London, London, WC1E 6JF, UK.<br /><searchLink fieldCode="AU" term="%22Chambers+ES%22">Chambers ES</searchLink>; Division of Infection and Immunity, University College London, London, WC1E 6JF, UK.<br /><searchLink fieldCode="AU" term="%22Subramanian+P%22">Subramanian P</searchLink>; Division of Infection and Immunity, University College London, London, WC1E 6JF, UK.<br /><searchLink fieldCode="AU" term="%22Patel+N%22">Patel N</searchLink>; Division of Infection and Immunity, University College London, London, WC1E 6JF, UK.<br /><searchLink fieldCode="AU" term="%22Virasami+A%22">Virasami A</searchLink>; Institute of Histopathology, Great Ormond Street Hospital for Children, University College London, London, WC1N 3JH, UK.<br /><searchLink fieldCode="AU" term="%22Sebire+NJ%22">Sebire NJ</searchLink>; Institute of Histopathology, Great Ormond Street Hospital for Children, University College London, London, WC1N 3JH, UK.<br /><searchLink fieldCode="AU" term="%22Kinsler+V%22">Kinsler V</searchLink>; Paediatric Dermatology Department, Great Ormond Street Hospital for Children, University College London, London, WC1N 3JH, UK.<br /><searchLink fieldCode="AU" term="%22Valdovinos+A%22">Valdovinos A</searchLink>; Buck Institute for Research on Aging, 8001 Redwood Blvd, Novato, CA, 94945, USA.<br /><searchLink fieldCode="AU" term="%22LeSaux+CJ%22">LeSaux CJ</searchLink>; Buck Institute for Research on Aging, 8001 Redwood Blvd, Novato, CA, 94945, USA.<br /><searchLink fieldCode="AU" term="%22Passos+JF%22">Passos JF</searchLink>; Institute for Cell and Molecular Biosciences & Newcastle University Institute for Ageing, Newcastle upon Tyne, NE1 7RU, UK.; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, 55905, MN, USA.<br /><searchLink fieldCode="AU" term="%22Antoniou+A%22">Antoniou A</searchLink>; Department of Applied Sciences, Faculty of Health and Life Sciences, Northumbria University, Newcastle Upon Tyne, NE1 8ST, UK.<br /><searchLink fieldCode="AU" term="%22Rustin+MHA%22">Rustin MHA</searchLink>; Division of Infection and Immunity, University College London, London, WC1E 6JF, UK.<br /><searchLink fieldCode="AU" term="%22Campisi+J%22">Campisi J</searchLink>; Buck Institute for Research on Aging, 8001 Redwood Blvd, Novato, CA, 94945, USA.; Lawrence Berkeley National Laboratory, 1 Cyclotron Rd, Berkeley, CA, 94720, USA.<br /><searchLink fieldCode="AU" term="%22Akbar+AN%22">Akbar AN</searchLink>; Division of Infection and Immunity, University College London, London, WC1E 6JF, UK. a.akbar@ucl.ac.uk.
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  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2019 Jun 03; Vol. 10 (1), pp. 2387. <i>Date of Electronic Publication: </i>2019 Jun 03.
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