Age at diagnosis, but not HPV type, is strongly associated with clinical course in recurrent respiratory papillomatosis.

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Title: Age at diagnosis, but not HPV type, is strongly associated with clinical course in recurrent respiratory papillomatosis.
Authors: Buchinsky FJ; Respiratory Papillomatosis Program, Allegheny Health Network, Pittsburgh, Pennsylvania, United States of America., Valentino WL; Drexel University College of Medicine, Philadelphia, Pennsylvania, United States of America., Ruszkay N; Drexel University College of Medicine, Philadelphia, Pennsylvania, United States of America., Powell E; Pittsburgh Clinical Genomics Laboratory, UPMC Magee-Women's Hospital, Pittsburgh, Pennsylvania, United States of America., Derkay CS; Department of Otolaryngology-Head and Neck Surgery, Eastern Virginia Medical School, Norfolk, Virginia, United States of America., Seedat RY; Department of Otorhinolaryngology, University of the Free State, Bloemfontein, South Africa., Uloza V; Department of Otorhinolaryngology, Lithuanian University of Health Sciences, Kaunas, Lithuania., Dikkers FG; Department of Otorhinolaryngology, Amsterdam UMC, Amsterdam, Netherlands., Tunkel DE; Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins Medical Institutions, Baltimore, Maryland, United States of America., Choi SS; Department of Otolaryngology and Communication Enhancement, Harvard Medical School-Boston Children's Hospital, Boston, Massachusetts, United States of America., Mortelliti AJ; Department of Otolaryngology and Communication Sciences, State University of New York Upstate Medical University, Syracuse, New York, United States of America., Campisi P; Department of Otolaryngology-Head and Neck Surgery, Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada., Ospina JC; Unit of Otorhinolaryngology and Maxillofacial Surgery, Pontificia Universidad Javeriana-Hospital San Ignacio, Bogotá, Colombia., Donne AJ; Department of Paediatric Otolaryngology, Alder Hey Children's NHS Foundation Trust, Liverpool, United Kingdom., Sataloff RT; Department of Otolaryngology-Head and Neck Surgery, Drexel University College of Medicine, Philadelphia, Pennsylvania, United States of America., Conley SF; Department of Otolaryngology and Communication Sciences, Medical College of Wisconsin, Milwaukee, Wisconsin, United States of America., McClay JE; Frisco ENT for Children, Dallas, Texas, United States of America., Friedman EM; Otolaryngology and Pediatrics, Baylor College of Medicine, Houston, Texas, United States of America., Elden L; Department Otolaryngology at Children's Hospital of Philadelphia, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America., Tylor DA; ENT Associates of Santa Barbara, Santa Barbara, California, United States of America., Rosen CA; Department of Otolaryngology, University of California San Francisco, San Francisco, California, United States of America., Smith LJ; University of Pittsburgh Voice Center, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America., Copley GJ; Red Cross War Memorial Children's Hospital, Cape Town, South Africa., Karas DE; Section of Otolaryngology, Yale University School of Medicine, New Haven, Connecticut, United States of America., Schweinfurth JM; Department of Otolaryngology, University of Mississippi Medical Center, Jackson, Mississippi, United States of America., Myer CM 3rd; Department of Otolaryngology-Head and Neck Surgery, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States of America., Wiatrak BJ; Pediatric Otolaryngology, Children's Hospital of Alabama, Birmingham, Alabama, United States of America., Dohar JE; Division of Pediatric Otolaryngology, Children's Hospital of Pittsburgh-UPMC, Pittsburgh, Pennsylvania, United States of America., Sobol SE; Department Otolaryngology at Children's Hospital of Philadelphia, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America., Bastian RW; Bastian Voice Institute, Downers Grove, Illinois, United States of America., Smith RJH; Division of Pediatric Otolaryngology, University of Iowa Hospitals and Clinics, Iowa City, Iowa, United States of America., Smith ME; Division of Otolaryngology-Head and Neck Surgery, University of Utah School of Medicine, Salt Lake City, Utah, United States of America., Wassie AM; Department of Otolaryngology-Head and Neck Surgery, Addis Ababa University, Addis Ababa, Ethiopia., Post JC; Respiratory Papillomatosis Program, Allegheny Health Network, Pittsburgh, Pennsylvania, United States of America., Ehrlich GD; Departments of Microbiology and Immunology, and Otolaryngology-Head and Neck Surgery and Center for Genomic Sciences, Institute of Molecular Medicine and Infectious Disease, Drexel University College of Medicine, Philadelphia, Pennsylvania, United States of America.
Source: PloS one [PLoS One] 2019 Jun 13; Vol. 14 (6), pp. e0216697. Date of Electronic Publication: 2019 Jun 13 (Print Publication: 2019).
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE
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  Data: Age at diagnosis, but not HPV type, is strongly associated with clinical course in recurrent respiratory papillomatosis.
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Department of Otorhinolaryngology, University of the Free State, Bloemfontein, South Africa.<br /><searchLink fieldCode="AU" term="%22Uloza+V%22">Uloza V</searchLink>; Department of Otorhinolaryngology, Lithuanian University of Health Sciences, Kaunas, Lithuania.<br /><searchLink fieldCode="AU" term="%22Dikkers+FG%22">Dikkers FG</searchLink>; Department of Otorhinolaryngology, Amsterdam UMC, Amsterdam, Netherlands.<br /><searchLink fieldCode="AU" term="%22Tunkel+DE%22">Tunkel DE</searchLink>; Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins Medical Institutions, Baltimore, Maryland, United States of America.<br /><searchLink fieldCode="AU" term="%22Choi+SS%22">Choi SS</searchLink>; Department of Otolaryngology and Communication Enhancement, Harvard Medical School-Boston Children's Hospital, Boston, Massachusetts, United States of America.<br /><searchLink fieldCode="AU" term="%22Mortelliti+AJ%22">Mortelliti AJ</searchLink>; Department of Otolaryngology and Communication Sciences, State University of New York Upstate Medical University, Syracuse, New York, United States of America.<br /><searchLink fieldCode="AU" term="%22Campisi+P%22">Campisi P</searchLink>; Department of Otolaryngology-Head and Neck Surgery, Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Ospina+JC%22">Ospina JC</searchLink>; Unit of Otorhinolaryngology and Maxillofacial Surgery, Pontificia Universidad Javeriana-Hospital San Ignacio, Bogotá, Colombia.<br /><searchLink fieldCode="AU" term="%22Donne+AJ%22">Donne AJ</searchLink>; Department of Paediatric Otolaryngology, Alder Hey Children's NHS Foundation Trust, Liverpool, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Sataloff+RT%22">Sataloff RT</searchLink>; Department of Otolaryngology-Head and Neck Surgery, Drexel University College of Medicine, Philadelphia, Pennsylvania, United States of America.<br /><searchLink fieldCode="AU" term="%22Conley+SF%22">Conley SF</searchLink>; Department of Otolaryngology and Communication Sciences, Medical College of Wisconsin, Milwaukee, Wisconsin, United States of America.<br /><searchLink fieldCode="AU" term="%22McClay+JE%22">McClay JE</searchLink>; Frisco ENT for Children, Dallas, Texas, United States of America.<br /><searchLink fieldCode="AU" term="%22Friedman+EM%22">Friedman EM</searchLink>; Otolaryngology and Pediatrics, Baylor College of Medicine, Houston, Texas, United States of America.<br /><searchLink fieldCode="AU" term="%22Elden+L%22">Elden L</searchLink>; Department Otolaryngology at Children's Hospital of Philadelphia, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.<br /><searchLink fieldCode="AU" term="%22Tylor+DA%22">Tylor DA</searchLink>; ENT Associates of Santa Barbara, Santa Barbara, California, United States of America.<br /><searchLink fieldCode="AU" term="%22Rosen+CA%22">Rosen CA</searchLink>; Department of Otolaryngology, University of California San Francisco, San Francisco, California, United States of America.<br /><searchLink fieldCode="AU" term="%22Smith+LJ%22">Smith LJ</searchLink>; University of Pittsburgh Voice Center, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America.<br /><searchLink fieldCode="AU" term="%22Copley+GJ%22">Copley GJ</searchLink>; Red Cross War Memorial Children's Hospital, Cape Town, South Africa.<br /><searchLink fieldCode="AU" term="%22Karas+DE%22">Karas DE</searchLink>; Section of Otolaryngology, Yale University School of Medicine, New Haven, Connecticut, United States of America.<br /><searchLink fieldCode="AU" term="%22Schweinfurth+JM%22">Schweinfurth JM</searchLink>; Department of Otolaryngology, University of Mississippi Medical Center, Jackson, Mississippi, United States of America.<br /><searchLink fieldCode="AU" term="%22Myer+CM+3rd%22">Myer CM 3rd</searchLink>; Department of Otolaryngology-Head and Neck Surgery, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States of America.<br /><searchLink fieldCode="AU" term="%22Wiatrak+BJ%22">Wiatrak BJ</searchLink>; Pediatric Otolaryngology, Children's Hospital of Alabama, Birmingham, Alabama, United States of America.<br /><searchLink fieldCode="AU" term="%22Dohar+JE%22">Dohar JE</searchLink>; Division of Pediatric Otolaryngology, Children's Hospital of Pittsburgh-UPMC, Pittsburgh, Pennsylvania, United States of America.<br /><searchLink fieldCode="AU" term="%22Sobol+SE%22">Sobol SE</searchLink>; Department Otolaryngology at Children's Hospital of Philadelphia, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.<br /><searchLink fieldCode="AU" term="%22Bastian+RW%22">Bastian RW</searchLink>; Bastian Voice Institute, Downers Grove, Illinois, United States of America.<br /><searchLink fieldCode="AU" term="%22Smith+RJH%22">Smith RJH</searchLink>; Division of Pediatric Otolaryngology, University of Iowa Hospitals and Clinics, Iowa City, Iowa, United States of America.<br /><searchLink fieldCode="AU" term="%22Smith+ME%22">Smith ME</searchLink>; Division of Otolaryngology-Head and Neck Surgery, University of Utah School of Medicine, Salt Lake City, Utah, United States of America.<br /><searchLink fieldCode="AU" term="%22Wassie+AM%22">Wassie AM</searchLink>; Department of Otolaryngology-Head and Neck Surgery, Addis Ababa University, Addis Ababa, Ethiopia.<br /><searchLink fieldCode="AU" term="%22Post+JC%22">Post JC</searchLink>; Respiratory Papillomatosis Program, Allegheny Health Network, Pittsburgh, Pennsylvania, United States of America.<br /><searchLink fieldCode="AU" term="%22Ehrlich+GD%22">Ehrlich GD</searchLink>; Departments of Microbiology and Immunology, and Otolaryngology-Head and Neck Surgery and Center for Genomic Sciences, Institute of Molecular Medicine and Infectious Disease, Drexel University College of Medicine, Philadelphia, Pennsylvania, United States of America.
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