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Domain-interface dynamics of CFTR revealed by stabilizing nanobodies.

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Title: Domain-interface dynamics of CFTR revealed by stabilizing nanobodies.
Authors: Sigoillot M; SFMB, Université Libre de Bruxelles (ULB), CP206/02, Boulevard du Triomphe, building BC, B-1050, Brussels, Belgium., Overtus M; SFMB, Université Libre de Bruxelles (ULB), CP206/02, Boulevard du Triomphe, building BC, B-1050, Brussels, Belgium., Grodecka M; SFMB, Université Libre de Bruxelles (ULB), CP206/02, Boulevard du Triomphe, building BC, B-1050, Brussels, Belgium., Scholl D; SFMB, Université Libre de Bruxelles (ULB), CP206/02, Boulevard du Triomphe, building BC, B-1050, Brussels, Belgium., Garcia-Pino A; Laboratoire de Microbiologie Moléculaire et Cellulaire, ULB CP300, rue des Professeurs Jeener et Brachet 12, B-6041, Charleroi, Belgium., Laeremans T; Structural Biology Brussels, Vrije Universiteit Brussel (VUB), Pleinlaan 2, B-1050, Brussels, Belgium.; VIB-VUB center for Structural Biology, VIB, Pleinlaan 2, B-1050, Brussels, Belgium., He L; Department of Biochemistry and Biophysics and Cystic Fibrosis Center, University of North Carolina-Chapel Hill, Chapel Hill, NC, 27599, USA., Pardon E; Structural Biology Brussels, Vrije Universiteit Brussel (VUB), Pleinlaan 2, B-1050, Brussels, Belgium.; VIB-VUB center for Structural Biology, VIB, Pleinlaan 2, B-1050, Brussels, Belgium., Hildebrandt E; Department of Cell Biology and Biochemistry and Center for Membrane Protein Research, Texas Tech University Health Sciences Center, 3601 4th Street, Stop 6540, Lubbock, TX, 79430, USA., Urbatsch I; Department of Cell Biology and Biochemistry and Center for Membrane Protein Research, Texas Tech University Health Sciences Center, 3601 4th Street, Stop 6540, Lubbock, TX, 79430, USA., Steyaert J; Structural Biology Brussels, Vrije Universiteit Brussel (VUB), Pleinlaan 2, B-1050, Brussels, Belgium.; VIB-VUB center for Structural Biology, VIB, Pleinlaan 2, B-1050, Brussels, Belgium., Riordan JR; Department of Biochemistry and Biophysics and Cystic Fibrosis Center, University of North Carolina-Chapel Hill, Chapel Hill, NC, 27599, USA., Govaerts C; SFMB, Université Libre de Bruxelles (ULB), CP206/02, Boulevard du Triomphe, building BC, B-1050, Brussels, Belgium. Cedric.Govaerts@ulb.ac.be.
Source: Nature communications [Nat Commun] 2019 Jun 14; Vol. 10 (1), pp. 2636. Date of Electronic Publication: 2019 Jun 14.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Domain-interface dynamics of CFTR revealed by stabilizing nanobodies.
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  Data: <searchLink fieldCode="AU" term="%22Sigoillot+M%22">Sigoillot M</searchLink>; SFMB, Université Libre de Bruxelles (ULB), CP206/02, Boulevard du Triomphe, building BC, B-1050, Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Overtus+M%22">Overtus M</searchLink>; SFMB, Université Libre de Bruxelles (ULB), CP206/02, Boulevard du Triomphe, building BC, B-1050, Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Grodecka+M%22">Grodecka M</searchLink>; SFMB, Université Libre de Bruxelles (ULB), CP206/02, Boulevard du Triomphe, building BC, B-1050, Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Scholl+D%22">Scholl D</searchLink>; SFMB, Université Libre de Bruxelles (ULB), CP206/02, Boulevard du Triomphe, building BC, B-1050, Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Garcia-Pino+A%22">Garcia-Pino A</searchLink>; Laboratoire de Microbiologie Moléculaire et Cellulaire, ULB CP300, rue des Professeurs Jeener et Brachet 12, B-6041, Charleroi, Belgium.<br /><searchLink fieldCode="AU" term="%22Laeremans+T%22">Laeremans T</searchLink>; Structural Biology Brussels, Vrije Universiteit Brussel (VUB), Pleinlaan 2, B-1050, Brussels, Belgium.; VIB-VUB center for Structural Biology, VIB, Pleinlaan 2, B-1050, Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22He+L%22">He L</searchLink>; Department of Biochemistry and Biophysics and Cystic Fibrosis Center, University of North Carolina-Chapel Hill, Chapel Hill, NC, 27599, USA.<br /><searchLink fieldCode="AU" term="%22Pardon+E%22">Pardon E</searchLink>; Structural Biology Brussels, Vrije Universiteit Brussel (VUB), Pleinlaan 2, B-1050, Brussels, Belgium.; VIB-VUB center for Structural Biology, VIB, Pleinlaan 2, B-1050, Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Hildebrandt+E%22">Hildebrandt E</searchLink>; Department of Cell Biology and Biochemistry and Center for Membrane Protein Research, Texas Tech University Health Sciences Center, 3601 4th Street, Stop 6540, Lubbock, TX, 79430, USA.<br /><searchLink fieldCode="AU" term="%22Urbatsch+I%22">Urbatsch I</searchLink>; Department of Cell Biology and Biochemistry and Center for Membrane Protein Research, Texas Tech University Health Sciences Center, 3601 4th Street, Stop 6540, Lubbock, TX, 79430, USA.<br /><searchLink fieldCode="AU" term="%22Steyaert+J%22">Steyaert J</searchLink>; Structural Biology Brussels, Vrije Universiteit Brussel (VUB), Pleinlaan 2, B-1050, Brussels, Belgium.; VIB-VUB center for Structural Biology, VIB, Pleinlaan 2, B-1050, Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Riordan+JR%22">Riordan JR</searchLink>; Department of Biochemistry and Biophysics and Cystic Fibrosis Center, University of North Carolina-Chapel Hill, Chapel Hill, NC, 27599, USA.<br /><searchLink fieldCode="AU" term="%22Govaerts+C%22">Govaerts C</searchLink>; SFMB, Université Libre de Bruxelles (ULB), CP206/02, Boulevard du Triomphe, building BC, B-1050, Brussels, Belgium. Cedric.Govaerts@ulb.ac.be.
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