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Discovery of Orally Active Hydroxyethylamine Based SPPL2a Inhibitors.

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Title: Discovery of Orally Active Hydroxyethylamine Based SPPL2a Inhibitors.
Authors: Velcicky J; Global Discovery Chemistry, and Autoimmunity Transplantation Inflammation, Novartis Institutes for BioMedical Research, CH-4002 Basel, Switzerland., Mathison CJN; The Genomics Institute of the Novartis Research Foundation, 10675 John Jay Hopkins Drive, San Diego, California 92121, United States., Nikulin V; The Genomics Institute of the Novartis Research Foundation, 10675 John Jay Hopkins Drive, San Diego, California 92121, United States., Pflieger D; Global Discovery Chemistry, and Autoimmunity Transplantation Inflammation, Novartis Institutes for BioMedical Research, CH-4002 Basel, Switzerland., Epple R; The Genomics Institute of the Novartis Research Foundation, 10675 John Jay Hopkins Drive, San Diego, California 92121, United States., Azimioara M; The Genomics Institute of the Novartis Research Foundation, 10675 John Jay Hopkins Drive, San Diego, California 92121, United States., Cow C; The Genomics Institute of the Novartis Research Foundation, 10675 John Jay Hopkins Drive, San Diego, California 92121, United States., Michellys PY; The Genomics Institute of the Novartis Research Foundation, 10675 John Jay Hopkins Drive, San Diego, California 92121, United States., Rigollier P; Global Discovery Chemistry, and Autoimmunity Transplantation Inflammation, Novartis Institutes for BioMedical Research, CH-4002 Basel, Switzerland., Beisner DR; The Genomics Institute of the Novartis Research Foundation, 10675 John Jay Hopkins Drive, San Diego, California 92121, United States., Bodendorf U; Global Discovery Chemistry, and Autoimmunity Transplantation Inflammation, Novartis Institutes for BioMedical Research, CH-4002 Basel, Switzerland., Guerini D; Global Discovery Chemistry, and Autoimmunity Transplantation Inflammation, Novartis Institutes for BioMedical Research, CH-4002 Basel, Switzerland., Liu B; The Genomics Institute of the Novartis Research Foundation, 10675 John Jay Hopkins Drive, San Diego, California 92121, United States., Wen B; The Genomics Institute of the Novartis Research Foundation, 10675 John Jay Hopkins Drive, San Diego, California 92121, United States., Zaharevitz S; The Genomics Institute of the Novartis Research Foundation, 10675 John Jay Hopkins Drive, San Diego, California 92121, United States., Brandl T; Global Discovery Chemistry, and Autoimmunity Transplantation Inflammation, Novartis Institutes for BioMedical Research, CH-4002 Basel, Switzerland.
Source: ACS medicinal chemistry letters [ACS Med Chem Lett] 2019 May 23; Vol. 10 (6), pp. 887-892. Date of Electronic Publication: 2019 May 23 (Print Publication: 2019).
Publication Type: Journal Article
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101521073 Publication Model: eCollection Cited Medium: Print ISSN: 1948-5875 (Print) Linking ISSN: 19485875 NLM ISO Abbreviation: ACS Med Chem Lett Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Discovery of Orally Active Hydroxyethylamine Based SPPL2a Inhibitors.
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  Data: <searchLink fieldCode="AU" term="%22Velcicky+J%22">Velcicky J</searchLink>; Global Discovery Chemistry, and Autoimmunity Transplantation Inflammation, Novartis Institutes for BioMedical Research, CH-4002 Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Mathison+CJN%22">Mathison CJN</searchLink>; The Genomics Institute of the Novartis Research Foundation, 10675 John Jay Hopkins Drive, San Diego, California 92121, United States.<br /><searchLink fieldCode="AU" term="%22Nikulin+V%22">Nikulin V</searchLink>; The Genomics Institute of the Novartis Research Foundation, 10675 John Jay Hopkins Drive, San Diego, California 92121, United States.<br /><searchLink fieldCode="AU" term="%22Pflieger+D%22">Pflieger D</searchLink>; Global Discovery Chemistry, and Autoimmunity Transplantation Inflammation, Novartis Institutes for BioMedical Research, CH-4002 Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Epple+R%22">Epple R</searchLink>; The Genomics Institute of the Novartis Research Foundation, 10675 John Jay Hopkins Drive, San Diego, California 92121, United States.<br /><searchLink fieldCode="AU" term="%22Azimioara+M%22">Azimioara M</searchLink>; The Genomics Institute of the Novartis Research Foundation, 10675 John Jay Hopkins Drive, San Diego, California 92121, United States.<br /><searchLink fieldCode="AU" term="%22Cow+C%22">Cow C</searchLink>; The Genomics Institute of the Novartis Research Foundation, 10675 John Jay Hopkins Drive, San Diego, California 92121, United States.<br /><searchLink fieldCode="AU" term="%22Michellys+PY%22">Michellys PY</searchLink>; The Genomics Institute of the Novartis Research Foundation, 10675 John Jay Hopkins Drive, San Diego, California 92121, United States.<br /><searchLink fieldCode="AU" term="%22Rigollier+P%22">Rigollier P</searchLink>; Global Discovery Chemistry, and Autoimmunity Transplantation Inflammation, Novartis Institutes for BioMedical Research, CH-4002 Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Beisner+DR%22">Beisner DR</searchLink>; The Genomics Institute of the Novartis Research Foundation, 10675 John Jay Hopkins Drive, San Diego, California 92121, United States.<br /><searchLink fieldCode="AU" term="%22Bodendorf+U%22">Bodendorf U</searchLink>; Global Discovery Chemistry, and Autoimmunity Transplantation Inflammation, Novartis Institutes for BioMedical Research, CH-4002 Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Guerini+D%22">Guerini D</searchLink>; Global Discovery Chemistry, and Autoimmunity Transplantation Inflammation, Novartis Institutes for BioMedical Research, CH-4002 Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Liu+B%22">Liu B</searchLink>; The Genomics Institute of the Novartis Research Foundation, 10675 John Jay Hopkins Drive, San Diego, California 92121, United States.<br /><searchLink fieldCode="AU" term="%22Wen+B%22">Wen B</searchLink>; The Genomics Institute of the Novartis Research Foundation, 10675 John Jay Hopkins Drive, San Diego, California 92121, United States.<br /><searchLink fieldCode="AU" term="%22Zaharevitz+S%22">Zaharevitz S</searchLink>; The Genomics Institute of the Novartis Research Foundation, 10675 John Jay Hopkins Drive, San Diego, California 92121, United States.<br /><searchLink fieldCode="AU" term="%22Brandl+T%22">Brandl T</searchLink>; Global Discovery Chemistry, and Autoimmunity Transplantation Inflammation, Novartis Institutes for BioMedical Research, CH-4002 Basel, Switzerland.
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