Recommendations for performing, interpreting and reporting hydrogen deuterium exchange mass spectrometry (HDX-MS) experiments.

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Title: Recommendations for performing, interpreting and reporting hydrogen deuterium exchange mass spectrometry (HDX-MS) experiments.
Authors: Masson GR; MRC Laboratory of Molecular Biology, Cambridge, UK. gmasson@mrc-lmb.cam.ac.uk., Burke JE; Department of Biochemistry and Microbiology, University of Victoria, Victoria, BC, Canada. jeburke@uvic.ca., Ahn NG; Department of Biochemistry, University of Colorado, Boulder, CO, USA., Anand GS; Department of Biological Science, National University of Singapore, Singapore, Singapore., Borchers C; Genome BC Proteomics Centre, University of Victoria, Victoria, BC, Canada., Brier S; Institut Pasteur, Chemistry and Structural Biology Department, Paris, France., Bou-Assaf GM; Biogen Idec, Cambridge, MA, USA., Engen JR; Department of Chemistry and Chemical Biology, Northeastern University, Boston, MA, USA., Englander SW; Department of Biochemistry and Biophysics, University of Pennsylvania, Philadelphia, PA, USA., Faber J; Novo Nordisk, Måløv, Denmark., Garlish R; UCB Celltech, Slough, UK., Griffin PR; Department of Integrative Structural and Computational Biology, Scripps Florida, The Scripps Research Institute, Jupiter, FL, USA., Gross ML; Department of Chemistry, Washington University in St. Louis, St. Louis, MO, USA., Guttman M; Department of Medicinal Chemistry, School of Pharmacy, University of Washington, Seattle, WA, USA., Hamuro Y; Johnson & Johnson Pharmaeutical Research and Development, Jersey City, NJ, USA., Heck AJR; Bijvoet Center for Biomolecular Research, Utrecht University, Utrecht, the Netherlands., Houde D; Codiak Biosciences, Cambridge, MA, USA., Iacob RE; Department of Chemistry and Chemical Biology, Northeastern University, Boston, MA, USA., Jørgensen TJD; Department of Biochemistry and Molecular Biology, University of Southern Denmark, Campusvej, Odense, Denmark., Kaltashov IA; Department of Chemistry, University of Massachusetts-Amherst, Amherst, MA, USA., Klinman JP; Department of Chemistry, University of California, Berkeley, Berkeley, CA, USA., Konermann L; Department of Chemistry, The University of Western Ontario, London, ON, Canada., Man P; Institute of Microbiology, Czech Academy of Sciences, Prague, Czech Republic., Mayne L; Department of Biochemistry and Biophysics, University of Pennsylvania, Philadelphia, PA, USA., Pascal BD; Department of Molecular Medicine, The Scripps Research Institute, Jupiter, FL, USA., Reichmann D; Department of Biological Chemistry, The Hebrew University of Jerusalem, Jerusalem, Israel., Skehel M; MRC Laboratory of Molecular Biology, Cambridge, UK., Snijder J; Department of Medicinal Chemistry, School of Pharmacy, University of Washington, Seattle, WA, USA., Strutzenberg TS; Department of Integrative Structural and Computational Biology, Scripps Florida, The Scripps Research Institute, Jupiter, FL, USA., Underbakke ES; Roy J. Carver Department of Biochemistry, Biophysics, and Molecular Biology, Iowa State University, Ames, IA, USA., Wagner C; Roche Innovation Center Penzberg, Penzberg, Germany., Wales TE; Department of Chemistry and Chemical Biology, Northeastern University, Boston, MA, USA., Walters BT; Department of Early Stage Pharmaceutical Development, Genentech, Inc., South San Francisco, CA, USA., Weis DD; Department of Pharmaceutical Chemistry, University of Kansas, Lawrence, KS, USA., Wilson DJ; Department of Chemistry, York University, Toronto, ON, Canada., Wintrode PL; Department of Pharmaceutical Sciences, University of Maryland School of Pharmacy, Baltimore, MD, USA., Zhang Z; Process Development, Amgen, Thousand Oaks, CA, USA., Zheng J; Department of Integrative Structural and Computational Biology, Scripps Florida, The Scripps Research Institute, Jupiter, FL, USA., Schriemer DC; Department of Biochemistry & Molecular Biology, University of Calgary, Calgary, AB, Canada. dschriem@ucalgary.ca., Rand KD; Department of Pharmacy, University of Copenhagen, Copenhagen, Denmark. kasper.rand@sund.ku.dk.
Source: Nature methods [Nat Methods] 2019 Jul; Vol. 16 (7), pp. 595-602. Date of Electronic Publication: 2019 Jun 27.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Review
Journal Info: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101215604 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1548-7105 (Electronic) Linking ISSN: 15487091 NLM ISO Abbreviation: Nat Methods Subsets: MEDLINE
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