Regulation of nuclear epigenome by mitochondrial DNA heteroplasmy.

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Title: Regulation of nuclear epigenome by mitochondrial DNA heteroplasmy.
Authors: Kopinski PK; Howard Hughes Medical Institute, University of Pennsylvania, Philadelphia, PA 19104.; Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104.; Center for Mitochondrial and Epigenomic Medicine, Children's Hospital of Philadelphia, Philadelphia, PA 19104., Janssen KA; Epigenetics Institute, University of Pennsylvania, Philadelphia, PA 19104.; Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104., Schaefer PM; Center for Mitochondrial and Epigenomic Medicine, Children's Hospital of Philadelphia, Philadelphia, PA 19104., Trefely S; Department of Cancer Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104.; A.J. Drexel Autism Institute, Drexel University, Philadelphia, PA 19104., Perry CE; Center for Mitochondrial and Epigenomic Medicine, Children's Hospital of Philadelphia, Philadelphia, PA 19104., Potluri P; Center for Mitochondrial and Epigenomic Medicine, Children's Hospital of Philadelphia, Philadelphia, PA 19104., Tintos-Hernandez JA; Center for Mitochondrial and Epigenomic Medicine, Children's Hospital of Philadelphia, Philadelphia, PA 19104., Singh LN; Center for Mitochondrial and Epigenomic Medicine, Children's Hospital of Philadelphia, Philadelphia, PA 19104., Karch KR; Epigenetics Institute, University of Pennsylvania, Philadelphia, PA 19104.; Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104., Campbell SL; Department of Cancer Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104., Doan MT; A.J. Drexel Autism Institute, Drexel University, Philadelphia, PA 19104., Jiang H; A.J. Drexel Autism Institute, Drexel University, Philadelphia, PA 19104., Nissim I; Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104., Nakamaru-Ogiso E; Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104., Wellen KE; Department of Cancer Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104., Snyder NW; A.J. Drexel Autism Institute, Drexel University, Philadelphia, PA 19104., Garcia BA; Epigenetics Institute, University of Pennsylvania, Philadelphia, PA 19104.; Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104., Wallace DC; Center for Mitochondrial and Epigenomic Medicine, Children's Hospital of Philadelphia, Philadelphia, PA 19104; WallaceD1@email.chop.edu.; Department of Pediatrics, Division of Human Genetics, The Children's Hospital of Philadelphia, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104.
Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2019 Aug 06; Vol. 116 (32), pp. 16028-16035. Date of Electronic Publication: 2019 Jun 28.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
Journal Info: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1091-6490
DOI:10.1073/pnas.1906896116