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Phenobarbital, Midazolam Pharmacokinetics, Effectiveness, and Drug-Drug Interaction in Asphyxiated Neonates Undergoing Therapeutic Hypothermia.

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Title: Phenobarbital, Midazolam Pharmacokinetics, Effectiveness, and Drug-Drug Interaction in Asphyxiated Neonates Undergoing Therapeutic Hypothermia.
Authors: Favié LMA; Department of Clinical Pharmacy, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands, L.M.A.Favie@umcutrecht.nl.; Department of Neonatology, Wilhelmina Children's Hospital, University Medical Center Utrecht and Utrecht University, Utrecht, The Netherlands, L.M.A.Favie@umcutrecht.nl., Groenendaal F; Department of Neonatology, Wilhelmina Children's Hospital, University Medical Center Utrecht and Utrecht University, Utrecht, The Netherlands.; Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, The Netherlands., van den Broek MPH; Department of Clinical Pharmacy, St. Antonius Hospital, Nieuwegein, The Netherlands., Rademaker CMA; Department of Clinical Pharmacy, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands., de Haan TR; Department of Neonatology, Emma Children's Hospital, Academic Medical Center, Amsterdam University Medical Center, Amsterdam, The Netherlands., van Straaten HLM; Department of Neonatology, Isala Clinics, Zwolle, The Netherlands., Dijk PH; Department of Neonatology, Groningen University Medical Centre, Groningen, The Netherlands., van Heijst A; Department of Neonatology, Radboud University Medical Center-Amalia Children's Hospital, Nijmegen, The Netherlands., Simons SHP; Division of Neonatology, Department of Pediatrics, Erasmus Medical Centre-Sophia Children's Hospital, Rotterdam, The Netherlands., Dijkman KP; Department of Neonatology, Máxima Medical Center Veldhoven, Veldhoven, The Netherlands., Rijken M; Department of Neonatology, Leiden University Medical Center, Leiden, The Netherlands., Zonnenberg IA; Department of Neonatology, VU University Medical Center, Amsterdam University Medical Center, Amsterdam, The Netherlands., Cools F; Department of Neonatology, UZ Brussel - Vrije Universiteit Brussel, Brussels, Belgium., Zecic A; Department of Neonatology, University Hospital Gent, Gent, Belgium., van der Lee JH; Paediatric Clinical Research Office, Emma Children's Hospital, Academic Medical Center, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, The Netherlands., Nuytemans DHGM; Clinical Research Coordinator PharmaCool Study, Amsterdam University Medical Center, Amsterdam, The Netherlands., van Bel F; Department of Neonatology, Wilhelmina Children's Hospital, University Medical Center Utrecht and Utrecht University, Utrecht, The Netherlands.; Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, The Netherlands., Egberts TCG; Department of Clinical Pharmacy, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.; Department of Pharmacoepidemiology and Clinical Pharmacology, Faculty of Science, Utrecht University, Utrecht, The Netherlands., Huitema ADR; Department of Clinical Pharmacy, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.; Department of Pharmacy and Pharmacology, Netherlands Cancer Institute, Amsterdam, The Netherlands.
Corporate Authors: on behalf of the PharmaCool study group
Source: Neonatology [Neonatology] 2019; Vol. 116 (2), pp. 154-162. Date of Electronic Publication: 2019 Jun 28.
Publication Type: Journal Article; Multicenter Study
Journal Info: Publisher: Karger Country of Publication: Switzerland NLM ID: 101286577 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1661-7819 (Electronic) Linking ISSN: 16617800 NLM ISO Abbreviation: Neonatology Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Phenobarbital, Midazolam Pharmacokinetics, Effectiveness, and Drug-Drug Interaction in Asphyxiated Neonates Undergoing Therapeutic Hypothermia.
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  Data: <searchLink fieldCode="AU" term="%22Favié+LMA%22">Favié LMA</searchLink>; Department of Clinical Pharmacy, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands, L.M.A.Favie@umcutrecht.nl.; Department of Neonatology, Wilhelmina Children's Hospital, University Medical Center Utrecht and Utrecht University, Utrecht, The Netherlands, L.M.A.Favie@umcutrecht.nl.<br /><searchLink fieldCode="AU" term="%22Groenendaal+F%22">Groenendaal F</searchLink>; Department of Neonatology, Wilhelmina Children's Hospital, University Medical Center Utrecht and Utrecht University, Utrecht, The Netherlands.; Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22van+den+Broek+MPH%22">van den Broek MPH</searchLink>; Department of Clinical Pharmacy, St. Antonius Hospital, Nieuwegein, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Rademaker+CMA%22">Rademaker CMA</searchLink>; Department of Clinical Pharmacy, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22de+Haan+TR%22">de Haan TR</searchLink>; Department of Neonatology, Emma Children's Hospital, Academic Medical Center, Amsterdam University Medical Center, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22van+Straaten+HLM%22">van Straaten HLM</searchLink>; Department of Neonatology, Isala Clinics, Zwolle, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Dijk+PH%22">Dijk PH</searchLink>; Department of Neonatology, Groningen University Medical Centre, Groningen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22van+Heijst+A%22">van Heijst A</searchLink>; Department of Neonatology, Radboud University Medical Center-Amalia Children's Hospital, Nijmegen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Simons+SHP%22">Simons SHP</searchLink>; Division of Neonatology, Department of Pediatrics, Erasmus Medical Centre-Sophia Children's Hospital, Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Dijkman+KP%22">Dijkman KP</searchLink>; Department of Neonatology, Máxima Medical Center Veldhoven, Veldhoven, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Rijken+M%22">Rijken M</searchLink>; Department of Neonatology, Leiden University Medical Center, Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Zonnenberg+IA%22">Zonnenberg IA</searchLink>; Department of Neonatology, VU University Medical Center, Amsterdam University Medical Center, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Cools+F%22">Cools F</searchLink>; Department of Neonatology, UZ Brussel - Vrije Universiteit Brussel, Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Zecic+A%22">Zecic A</searchLink>; Department of Neonatology, University Hospital Gent, Gent, Belgium.<br /><searchLink fieldCode="AU" term="%22van+der+Lee+JH%22">van der Lee JH</searchLink>; Paediatric Clinical Research Office, Emma Children's Hospital, Academic Medical Center, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Nuytemans+DHGM%22">Nuytemans DHGM</searchLink>; Clinical Research Coordinator PharmaCool Study, Amsterdam University Medical Center, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22van+Bel+F%22">van Bel F</searchLink>; Department of Neonatology, Wilhelmina Children's Hospital, University Medical Center Utrecht and Utrecht University, Utrecht, The Netherlands.; Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Egberts+TCG%22">Egberts TCG</searchLink>; Department of Clinical Pharmacy, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.; Department of Pharmacoepidemiology and Clinical Pharmacology, Faculty of Science, Utrecht University, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Huitema+ADR%22">Huitema ADR</searchLink>; Department of Clinical Pharmacy, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.; Department of Pharmacy and Pharmacology, Netherlands Cancer Institute, Amsterdam, The Netherlands.
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  Data: <searchLink fieldCode="JN" term="%22101286577%22">Neonatology</searchLink> [Neonatology] 2019; Vol. 116 (2), pp. 154-162. <i>Date of Electronic Publication: </i>2019 Jun 28.
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