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The integrin αvβ6 drives pancreatic cancer through diverse mechanisms and represents an effective target for therapy.

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Title: The integrin αvβ6 drives pancreatic cancer through diverse mechanisms and represents an effective target for therapy.
Authors: Reader CS; Centre for Tumour Biology, Barts Cancer Institute, CRUK Centre of Excellence, Queen Mary University of London, John Vane Science Centre, London, UK., Vallath S; Centre for Tumour Biology, Barts Cancer Institute, CRUK Centre of Excellence, Queen Mary University of London, John Vane Science Centre, London, UK., Steele CW; Cancer Research UK Beatson Institute, Glasgow, UK., Haider S; Institute of Cancer Research, London, UK., Brentnall A; Centre for Cancer Prevention, Wolfson Institute of Preventive Medicine, Queen Mary University of London, London, UK., Desai A; Centre for Tumour Biology, Barts Cancer Institute, CRUK Centre of Excellence, Queen Mary University of London, John Vane Science Centre, London, UK., Moore KM; Centre for Tumour Biology, Barts Cancer Institute, CRUK Centre of Excellence, Queen Mary University of London, John Vane Science Centre, London, UK., Jamieson NB; Academic Unit of Surgery, School of Medicine, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow Royal Infirmary, Glasgow, UK.; West of Scotland Pancreatic Unit, Glasgow Royal Infirmary, Glasgow, UK., Chang D; Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow, UK., Bailey P; Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow, UK., Scarpa A; ARC-NET Research Centre for Applied Research on Cancer, University of Verona, Verona, Italy., Lawlor R; ARC-NET Research Centre for Applied Research on Cancer, University of Verona, Verona, Italy., Chelala C; Centre for Molecular Oncology, Barts Cancer Institute, CRUK Centre of Excellence, Queen Mary University of London, John Vane Science Centre, London, UK., Keyse SM; Division of Cancer Research, University of Dundee, James Arrott Drive, Ninewells Hospital and Medical School, Dundee, UK., Biankin A; Centre for Molecular Oncology, Barts Cancer Institute, CRUK Centre of Excellence, Queen Mary University of London, John Vane Science Centre, London, UK., Morton JP; Cancer Research UK Beatson Institute, Glasgow, UK., Evans TJ; Cancer Research UK Beatson Institute, Glasgow, UK.; Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow, UK., Barry ST; Bioscience, Oncology R&D, AstraZeneca, Cambridge, UK., Sansom OJ; Cancer Research UK Beatson Institute, Glasgow, UK., Kocher HM; Centre for Tumour Biology, Barts Cancer Institute, CRUK Centre of Excellence, Queen Mary University of London, John Vane Science Centre, London, UK., Marshall JF; Centre for Tumour Biology, Barts Cancer Institute, CRUK Centre of Excellence, Queen Mary University of London, John Vane Science Centre, London, UK.
Source: The Journal of pathology [J Pathol] 2019 Nov; Vol. 249 (3), pp. 332-342. Date of Electronic Publication: 2019 Jul 30.
Publication Type: Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
Journal Info: Publisher: John Wiley And Sons Country of Publication: England NLM ID: 0204634 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-9896 (Electronic) Linking ISSN: 00223417 NLM ISO Abbreviation: J Pathol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: The integrin αvβ6 drives pancreatic cancer through diverse mechanisms and represents an effective target for therapy.
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  Data: <searchLink fieldCode="AU" term="%22Reader+CS%22">Reader CS</searchLink>; Centre for Tumour Biology, Barts Cancer Institute, CRUK Centre of Excellence, Queen Mary University of London, John Vane Science Centre, London, UK.<br /><searchLink fieldCode="AU" term="%22Vallath+S%22">Vallath S</searchLink>; Centre for Tumour Biology, Barts Cancer Institute, CRUK Centre of Excellence, Queen Mary University of London, John Vane Science Centre, London, UK.<br /><searchLink fieldCode="AU" term="%22Steele+CW%22">Steele CW</searchLink>; Cancer Research UK Beatson Institute, Glasgow, UK.<br /><searchLink fieldCode="AU" term="%22Haider+S%22">Haider S</searchLink>; Institute of Cancer Research, London, UK.<br /><searchLink fieldCode="AU" term="%22Brentnall+A%22">Brentnall A</searchLink>; Centre for Cancer Prevention, Wolfson Institute of Preventive Medicine, Queen Mary University of London, London, UK.<br /><searchLink fieldCode="AU" term="%22Desai+A%22">Desai A</searchLink>; Centre for Tumour Biology, Barts Cancer Institute, CRUK Centre of Excellence, Queen Mary University of London, John Vane Science Centre, London, UK.<br /><searchLink fieldCode="AU" term="%22Moore+KM%22">Moore KM</searchLink>; Centre for Tumour Biology, Barts Cancer Institute, CRUK Centre of Excellence, Queen Mary University of London, John Vane Science Centre, London, UK.<br /><searchLink fieldCode="AU" term="%22Jamieson+NB%22">Jamieson NB</searchLink>; Academic Unit of Surgery, School of Medicine, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow Royal Infirmary, Glasgow, UK.; West of Scotland Pancreatic Unit, Glasgow Royal Infirmary, Glasgow, UK.<br /><searchLink fieldCode="AU" term="%22Chang+D%22">Chang D</searchLink>; Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow, UK.<br /><searchLink fieldCode="AU" term="%22Bailey+P%22">Bailey P</searchLink>; Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow, UK.<br /><searchLink fieldCode="AU" term="%22Scarpa+A%22">Scarpa A</searchLink>; ARC-NET Research Centre for Applied Research on Cancer, University of Verona, Verona, Italy.<br /><searchLink fieldCode="AU" term="%22Lawlor+R%22">Lawlor R</searchLink>; ARC-NET Research Centre for Applied Research on Cancer, University of Verona, Verona, Italy.<br /><searchLink fieldCode="AU" term="%22Chelala+C%22">Chelala C</searchLink>; Centre for Molecular Oncology, Barts Cancer Institute, CRUK Centre of Excellence, Queen Mary University of London, John Vane Science Centre, London, UK.<br /><searchLink fieldCode="AU" term="%22Keyse+SM%22">Keyse SM</searchLink>; Division of Cancer Research, University of Dundee, James Arrott Drive, Ninewells Hospital and Medical School, Dundee, UK.<br /><searchLink fieldCode="AU" term="%22Biankin+A%22">Biankin A</searchLink>; Centre for Molecular Oncology, Barts Cancer Institute, CRUK Centre of Excellence, Queen Mary University of London, John Vane Science Centre, London, UK.<br /><searchLink fieldCode="AU" term="%22Morton+JP%22">Morton JP</searchLink>; Cancer Research UK Beatson Institute, Glasgow, UK.<br /><searchLink fieldCode="AU" term="%22Evans+TJ%22">Evans TJ</searchLink>; Cancer Research UK Beatson Institute, Glasgow, UK.; Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow, UK.<br /><searchLink fieldCode="AU" term="%22Barry+ST%22">Barry ST</searchLink>; Bioscience, Oncology R&D, AstraZeneca, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Sansom+OJ%22">Sansom OJ</searchLink>; Cancer Research UK Beatson Institute, Glasgow, UK.<br /><searchLink fieldCode="AU" term="%22Kocher+HM%22">Kocher HM</searchLink>; Centre for Tumour Biology, Barts Cancer Institute, CRUK Centre of Excellence, Queen Mary University of London, John Vane Science Centre, London, UK.<br /><searchLink fieldCode="AU" term="%22Marshall+JF%22">Marshall JF</searchLink>; Centre for Tumour Biology, Barts Cancer Institute, CRUK Centre of Excellence, Queen Mary University of London, John Vane Science Centre, London, UK.
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  Data: <searchLink fieldCode="JN" term="%220204634%22">The Journal of pathology</searchLink> [J Pathol] 2019 Nov; Vol. 249 (3), pp. 332-342. <i>Date of Electronic Publication: </i>2019 Jul 30.
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        Value: 10.1002/path.5320
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