The integrin αvβ6 drives pancreatic cancer through diverse mechanisms and represents an effective target for therapy. - Reader CS; Vallath S; Steele CW; Haider S; Brentnall A; Desai A; Moore KM; Jamieson NB; Chang D; Bailey P; Scarpa A; Lawlor R; et al. (The Journal of pathology, 2019)