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Paternal-age-related de novo mutations and risk for five disorders.

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Title: Paternal-age-related de novo mutations and risk for five disorders.
Authors: Taylor JL; Department of Psychiatry, Brigham and Woman's Hospital, Boston, MA, 02115, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, 02412, USA., Debost JPG; National Centre for Register-based Research, Department of Economics and Business, Aarhus University, Aarhus, 8210, Denmark.; The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Aarhus, 8210, Denmark.; Aarhus University Hospital, Risskov, Department P, Aarhus, 8200, Denmark., Morton SU; Division of Newborn Medicine, Boston Children's Hospital and Harvard Medical School, Boston, MA, 02115, USA., Wigdor EM; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, 02412, USA.; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, 02114, USA., Heyne HO; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, 02412, USA.; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, 02114, USA., Lal D; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA.; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, 02114, USA.; Cologne Center for Genomics, University of Cologne, Cologne, 50923, Germany.; Psychiatric and Neurodevelopmental Genetics Unit, Department of Psychiatry, Massachusetts General Hospital, Boston, MA, 02114, USA., Howrigan DP; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA.; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, 02114, USA., Bloemendal A; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, 02412, USA.; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, 02114, USA., Larsen JT; National Centre for Register-based Research, Department of Economics and Business, Aarhus University, Aarhus, 8210, Denmark.; The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Aarhus, 8210, Denmark., Kosmicki JA; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, 02412, USA.; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, 02114, USA.; Program in Genetics and Genomics, Biological and Biomedical Sciences, Harvard Medical School, Boston, MA, 02115, USA., Weiner DJ; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, 02412, USA.; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, 02114, USA., Homsy J; Department of Genetics, Harvard Medical School, Boston, MA, 02115, USA., Seidman JG; Department of Genetics, Harvard Medical School, Boston, MA, 02115, USA., Seidman CE; Department of Genetics, Harvard Medical School, Boston, MA, 02115, USA.; Cardiovascular Division, Brigham and Women's Hospital, Boston, MA, 02115, USA.; Howard Hughes Medical Institute, Harvard Medical School, Boston, MA, 02115, USA., Agerbo E; National Centre for Register-based Research, Department of Economics and Business, Aarhus University, Aarhus, 8210, Denmark.; The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Aarhus, 8210, Denmark.; Centre for Integrated Register-based Research, CIRRAU, Aarhus University, Aarhus, 8210, Denmark., McGrath JJ; National Centre for Register-based Research, Department of Economics and Business, Aarhus University, Aarhus, 8210, Denmark.; Queensland Brain Institute, The University of Queensland, Brisbane, 4072, Queensland, Australia.; Queensland Centre for Mental Health Research, The Park Centre for Mental Health, Richlands, 4076, Queensland, Australia., Mortensen PB; National Centre for Register-based Research, Department of Economics and Business, Aarhus University, Aarhus, 8210, Denmark.; The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Aarhus, 8210, Denmark.; Centre for Integrated Register-based Research, CIRRAU, Aarhus University, Aarhus, 8210, Denmark.; Department of Biomedicine and iSEQ, Centre for Integrative Sequencing, Aarhus University, Aarhus, 08210, Denmark., Petersen L; National Centre for Register-based Research, Department of Economics and Business, Aarhus University, Aarhus, 8210, Denmark.; The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Aarhus, 8210, Denmark., Daly MJ; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, 02412, USA.; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, 02114, USA., Robinson EB; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA. erobinso@hsph.harvard.edu.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, 02412, USA. erobinso@hsph.harvard.edu.; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, 02114, USA. erobinso@hsph.harvard.edu.; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, 02115, USA. erobinso@hsph.harvard.edu.
Source: Nature communications [Nat Commun] 2019 Jul 10; Vol. 10 (1), pp. 3043. Date of Electronic Publication: 2019 Jul 10.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2041-1723
DOI:10.1038/s41467-019-11039-6