Enhanced agonist residence time, internalization rate and signalling of the GIP receptor variant [E354Q] facilitate receptor desensitization and long-term impairment of the GIP system.
Saved in:
| Title: | Enhanced agonist residence time, internalization rate and signalling of the GIP receptor variant [E354Q] facilitate receptor desensitization and long-term impairment of the GIP system. |
|---|---|
| Authors: | Gabe MBN; Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., van der Velden WJC; Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Gadgaard S; Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Smit FX; Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Hartmann B; Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen, Denmark., Bräuner-Osborne H; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Rosenkilde MM; Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark. |
| Source: | Basic & clinical pharmacology & toxicology [Basic Clin Pharmacol Toxicol] 2020 Jun; Vol. 126 Suppl 6, pp. 122-132. Date of Electronic Publication: 2019 Aug 19. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Blackwell Country of Publication: England NLM ID: 101208422 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1742-7843 (Electronic) Linking ISSN: 17427835 NLM ISO Abbreviation: Basic Clin Pharmacol Toxicol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
|
Full text is not displayed to guests.
Login for full access.
|
|
| FullText | Links: – Type: pdflink Text: Availability: 1 |
|---|---|
| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 31299132 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
| IllustrationInfo | |
| Items | – Name: Title Label: Title Group: Ti Data: Enhanced agonist residence time, internalization rate and signalling of the GIP receptor variant [E354Q] facilitate receptor desensitization and long-term impairment of the GIP system. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Gabe+MBN%22">Gabe MBN</searchLink>; Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22van+der+Velden+WJC%22">van der Velden WJC</searchLink>; Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Gadgaard+S%22">Gadgaard S</searchLink>; Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Smit+FX%22">Smit FX</searchLink>; Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Hartmann+B%22">Hartmann B</searchLink>; Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Bräuner-Osborne+H%22">Bräuner-Osborne H</searchLink>; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Rosenkilde+MM%22">Rosenkilde MM</searchLink>; Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101208422%22">Basic & clinical pharmacology & toxicology</searchLink> [Basic Clin Pharmacol Toxicol] 2020 Jun; Vol. 126 Suppl 6, pp. 122-132. <i>Date of Electronic Publication: </i>2019 Aug 19. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Blackwell%22">Blackwell </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101208422 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1742-7843 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2217427835%22">17427835 </searchLink><i>NLM ISO Abbreviation: </i>Basic Clin Pharmacol Toxicol <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=31299132 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1111/bcpt.13289 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 122 Titles: – TitleFull: Enhanced agonist residence time, internalization rate and signalling of the GIP receptor variant [E354Q] facilitate receptor desensitization and long-term impairment of the GIP system. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Gabe MBN – PersonEntity: Name: NameFull: van der Velden WJC – PersonEntity: Name: NameFull: Gadgaard S – PersonEntity: Name: NameFull: Smit FX – PersonEntity: Name: NameFull: Hartmann B – PersonEntity: Name: NameFull: Bräuner-Osborne H – PersonEntity: Name: NameFull: Rosenkilde MM IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 06 Text: 2020 Jun Type: published Y: 2020 Identifiers: – Type: issn-electronic Value: 1742-7843 Numbering: – Type: volume Value: 126 Suppl 6 Titles: – TitleFull: Basic & clinical pharmacology & toxicology Type: main |
| ResultId | 1 |
