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First-in-Human Randomized Study to Assess the Safety and Immunogenicity of an Investigational Respiratory Syncytial Virus (RSV) Vaccine Based on Chimpanzee-Adenovirus-155 Viral Vector-Expressing RSV Fusion, Nucleocapsid, and Antitermination Viral Proteins in Healthy Adults.

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Title: First-in-Human Randomized Study to Assess the Safety and Immunogenicity of an Investigational Respiratory Syncytial Virus (RSV) Vaccine Based on Chimpanzee-Adenovirus-155 Viral Vector-Expressing RSV Fusion, Nucleocapsid, and Antitermination Viral Proteins in Healthy Adults.
Authors: Cicconi P; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, United Kingdom., Jones C; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, United Kingdom., Sarkar E; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, United Kingdom., Silva-Reyes L; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, United Kingdom., Klenerman P; Nuffield Department of Medicine, University of Oxford, United Kingdom., de Lara C; Nuffield Department of Medicine, University of Oxford, United Kingdom., Hutchings C; Nuffield Department of Medicine, University of Oxford, United Kingdom., Moris P; GSK, Rixensart, Belgium., Janssens M; GSK, Rixensart, Belgium., Fissette LA; GSK, Wavre, Belgium., Picciolato M; GSK, Rixensart, Belgium., Leach A; GSK, Rockville, Maryland., Gonzalez-Lopez A; GSK, Rockville, Maryland., Dieussaert I; GSK, Rockville, Maryland., Snape MD; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, United Kingdom.; National Institute for Health Research Oxford Biomedical Centre, United Kingdom.
Source: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America [Clin Infect Dis] 2020 May 06; Vol. 70 (10), pp. 2073-2081.
Publication Type: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Oxford University Press Country of Publication: United States NLM ID: 9203213 Publication Model: Print Cited Medium: Internet ISSN: 1537-6591 (Electronic) Linking ISSN: 10584838 NLM ISO Abbreviation: Clin Infect Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: First-in-Human Randomized Study to Assess the Safety and Immunogenicity of an Investigational Respiratory Syncytial Virus (RSV) Vaccine Based on Chimpanzee-Adenovirus-155 Viral Vector-Expressing RSV Fusion, Nucleocapsid, and Antitermination Viral Proteins in Healthy Adults.
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  Data: <searchLink fieldCode="AU" term="%22Cicconi+P%22">Cicconi P</searchLink>; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Jones+C%22">Jones C</searchLink>; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Sarkar+E%22">Sarkar E</searchLink>; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Silva-Reyes+L%22">Silva-Reyes L</searchLink>; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Klenerman+P%22">Klenerman P</searchLink>; Nuffield Department of Medicine, University of Oxford, United Kingdom.<br /><searchLink fieldCode="AU" term="%22de+Lara+C%22">de Lara C</searchLink>; Nuffield Department of Medicine, University of Oxford, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Hutchings+C%22">Hutchings C</searchLink>; Nuffield Department of Medicine, University of Oxford, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Moris+P%22">Moris P</searchLink>; GSK, Rixensart, Belgium.<br /><searchLink fieldCode="AU" term="%22Janssens+M%22">Janssens M</searchLink>; GSK, Rixensart, Belgium.<br /><searchLink fieldCode="AU" term="%22Fissette+LA%22">Fissette LA</searchLink>; GSK, Wavre, Belgium.<br /><searchLink fieldCode="AU" term="%22Picciolato+M%22">Picciolato M</searchLink>; GSK, Rixensart, Belgium.<br /><searchLink fieldCode="AU" term="%22Leach+A%22">Leach A</searchLink>; GSK, Rockville, Maryland.<br /><searchLink fieldCode="AU" term="%22Gonzalez-Lopez+A%22">Gonzalez-Lopez A</searchLink>; GSK, Rockville, Maryland.<br /><searchLink fieldCode="AU" term="%22Dieussaert+I%22">Dieussaert I</searchLink>; GSK, Rockville, Maryland.<br /><searchLink fieldCode="AU" term="%22Snape+MD%22">Snape MD</searchLink>; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, United Kingdom.; National Institute for Health Research Oxford Biomedical Centre, United Kingdom.
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  Data: <searchLink fieldCode="JN" term="%229203213%22">Clinical infectious diseases : an official publication of the Infectious Diseases Society of America</searchLink> [Clin Infect Dis] 2020 May 06; Vol. 70 (10), pp. 2073-2081.
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