Elevated neoantigen levels in tumors with somatic mutations in the HLA-A, HLA-B, HLA-C and B2M genes.

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Title: Elevated neoantigen levels in tumors with somatic mutations in the HLA-A, HLA-B, HLA-C and B2M genes.
Authors: Castro A; Department of Medicine, Division of Medical Genetics, University of California San Diego, La Jolla, CA, 92093, USA.; Bioinformatics and Systems Biology Program, University of California San Diego, La Jolla, CA, 92093, USA., Ozturk K; Department of Medicine, Division of Medical Genetics, University of California San Diego, La Jolla, CA, 92093, USA.; Bioinformatics and Systems Biology Program, University of California San Diego, La Jolla, CA, 92093, USA., Pyke RM; Department of Medicine, Division of Medical Genetics, University of California San Diego, La Jolla, CA, 92093, USA.; Bioinformatics and Systems Biology Program, University of California San Diego, La Jolla, CA, 92093, USA., Xian S; Department of Medicine, Division of Medical Genetics, University of California San Diego, La Jolla, CA, 92093, USA., Zanetti M; Moores Cancer Center, University of California San Diego, La Jolla, CA, 92093, USA.; The Laboratory of Immunology and Department of Medicine, University of California San Diego, La Jolla, CA, 92093, USA., Carter H; Department of Medicine, Division of Medical Genetics, University of California San Diego, La Jolla, CA, 92093, USA. hkcarter@ucsd.edu.; Bioinformatics and Systems Biology Program, University of California San Diego, La Jolla, CA, 92093, USA. hkcarter@ucsd.edu.; Moores Cancer Center, University of California San Diego, La Jolla, CA, 92093, USA. hkcarter@ucsd.edu.; CIFAR, MaRS Centre, West Tower, 661 University Ave., Suite 505, Toronto, ON, M5G 1M1, Canada. hkcarter@ucsd.edu.
Source: BMC medical genomics [BMC Med Genomics] 2019 Jul 25; Vol. 12 (Suppl 6), pp. 107. Date of Electronic Publication: 2019 Jul 25.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101319628 Publication Model: Electronic Cited Medium: Internet ISSN: 1755-8794 (Electronic) Linking ISSN: 17558794 NLM ISO Abbreviation: BMC Med Genomics Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1755-8794
DOI:10.1186/s12920-019-0544-1