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Design, synthesis and evaluation of novel, potent DNA alkylating agents and their antibody-drug conjugates (ADCs).

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Bibliographic Details
Title: Design, synthesis and evaluation of novel, potent DNA alkylating agents and their antibody-drug conjugates (ADCs).
Authors: Reid EE; ImmunoGen, Inc., 830 Winter Street, Waltham, MA 02451, United States., Archer KE; ImmunoGen, Inc., 830 Winter Street, Waltham, MA 02451, United States., Shizuka M; ImmunoGen, Inc., 830 Winter Street, Waltham, MA 02451, United States., McShea MA; ImmunoGen, Inc., 830 Winter Street, Waltham, MA 02451, United States., Maloney EK; ImmunoGen, Inc., 830 Winter Street, Waltham, MA 02451, United States., Ab O; ImmunoGen, Inc., 830 Winter Street, Waltham, MA 02451, United States., Lanieri L; ImmunoGen, Inc., 830 Winter Street, Waltham, MA 02451, United States., Wilhelm A; ImmunoGen, Inc., 830 Winter Street, Waltham, MA 02451, United States., Ponte JF; ImmunoGen, Inc., 830 Winter Street, Waltham, MA 02451, United States., Yoder NC; ImmunoGen, Inc., 830 Winter Street, Waltham, MA 02451, United States., Chari RVJ; ImmunoGen, Inc., 830 Winter Street, Waltham, MA 02451, United States., Miller ML; ImmunoGen, Inc., 830 Winter Street, Waltham, MA 02451, United States. Electronic address: michael.miller@immunogen.com.
Source: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2019 Sep 01; Vol. 29 (17), pp. 2455-2458. Date of Electronic Publication: 2019 Jul 19.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9107377 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-3405 (Electronic) Linking ISSN: 0960894X NLM ISO Abbreviation: Bioorg Med Chem Lett Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1464-3405
DOI:10.1016/j.bmcl.2019.07.031