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Final results from GCIG/ENGOT/AGO-OVAR 12, a randomised placebo-controlled phase III trial of nintedanib combined with chemotherapy for newly diagnosed advanced ovarian cancer.

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Title: Final results from GCIG/ENGOT/AGO-OVAR 12, a randomised placebo-controlled phase III trial of nintedanib combined with chemotherapy for newly diagnosed advanced ovarian cancer.
Authors: Ray-Coquard I; GINECO and Medical Oncology Department, Centre Léon Bérard, University Claude Bernard Lyon, Lyon, France., Cibula D; AGO and Oncogynecologic Center, Department of Obstetrics and Gynecology, General Faculty Hospital, Charles University of Prague, Prague, Czech Republic., Mirza MR; NSGO and Department of Oncology, Rigshospitalet Copenhagen University Hospital, Copenhagen, Denmark., Reuss A; AGO and Coordinating Center for Clinical Trials, Philipps-University of Marburg, Marburg, Germany., Ricci C; MITO and Division of Gynecologic Oncology, Department of Women and Children's Health and Public Health, Fondazione Policlinico Gemelli IRCCS, Rome, Italy., Colombo N; MaNGO and European Institute of Oncology and University of Milan Bicocca, Milan, Italy., Koch H; AGO Austria and Department of Obstetrics and Gynecology, Paracelsus Medical University, Salzburg, Austria., Goffin F; BGOG and CHU de Liège, University of Liège, Liège, Belgium., González-Martin A; GEICO and Medical Oncology Department, Clínica Universidad de Navarra, Madrid, Spain., Ottevanger PB; DGOG and Department of Medical Oncology, Radboud University Medical Centre, Nijmegen, The Netherlands., Baumann K; AGO and Department of Gynecology, Klinikum der Stadt Ludwigshafen GmbH, Ludwigshafen, Germany., Bjørge L; NSGO and Department of Gynecology, Haukeland Universitetssykehus, Bergen, Norway.; Center for Cancer Biomarkers CCBIO, Department of Clinical Science, University of Bergen, Bergen, Norway., Lesoin A; GINECO and Department of Gynecologic Cancer and Medical Oncology, Centre Oscar Lambret, Lille, France., Burges A; AGO and Department of Obstetrics and Gynecology, University Hospital, LMU Munich, Germany., Rosenberg P; NSGO and Department of Oncology, University Hospital Linköping, Linköping, Sweden., Gropp-Meier M; AGO and Department of Gynecology and Obstetrics, Oberschwabenklinik, Krankenhaus St. Elisabeth, Ravensburg, Germany., Harrela M; NSGO and Department of Gynoncology and Gynecology and Obstetrics, Kymenlaakso Central Hospital, Kotka, Finland., Harter P; AGO and Department of Gynecology and Gynecologic Oncology, Kliniken Essen Mitte, Essen, Germany., Frenel JS; GINECO and Centre René Gauducheau, Institut de Cancerologie de l'Ouest, Saint Herblain, France., Minarik T; NSGO and National Institute of Oncology, Bratislava, Slovakia., Pisano C; MITO and Department of Uro-Gynecologic Oncology, Istituto Nazionale per Io Studio e la Cura dei Tumori 'Fondazione G. Pascale' IRCCS, Naples, Italy., Hasenburg A; AGO and Department of Obstetrics and Gynecology, University Medical Center, Mainz, Germany., Merger M; Oncology Medicine, Boehringer Ingelheim International GmbH, Biberach, Germany., du Bois A; AGO and Department of Gynecology and Gynecologic Oncology, Kliniken Essen Mitte, Essen, Germany.
Corporate Authors: AGO Study Group-led GCIG/ENGOT Intergroup Consortium
Source: International journal of cancer [Int J Cancer] 2020 Jan 15; Vol. 146 (2), pp. 439-448. Date of Electronic Publication: 2019 Sep 06.
Publication Type: Clinical Trial, Phase III; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 0042124 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-0215 (Electronic) Linking ISSN: 00207136 NLM ISO Abbreviation: Int J Cancer Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Final results from GCIG/ENGOT/AGO-OVAR 12, a randomised placebo-controlled phase III trial of nintedanib combined with chemotherapy for newly diagnosed advanced ovarian cancer.
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  Data: <searchLink fieldCode="AU" term="%22Ray-Coquard+I%22">Ray-Coquard I</searchLink>; GINECO and Medical Oncology Department, Centre Léon Bérard, University Claude Bernard Lyon, Lyon, France.<br /><searchLink fieldCode="AU" term="%22Cibula+D%22">Cibula D</searchLink>; AGO and Oncogynecologic Center, Department of Obstetrics and Gynecology, General Faculty Hospital, Charles University of Prague, Prague, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Mirza+MR%22">Mirza MR</searchLink>; NSGO and Department of Oncology, Rigshospitalet Copenhagen University Hospital, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Reuss+A%22">Reuss A</searchLink>; AGO and Coordinating Center for Clinical Trials, Philipps-University of Marburg, Marburg, Germany.<br /><searchLink fieldCode="AU" term="%22Ricci+C%22">Ricci C</searchLink>; MITO and Division of Gynecologic Oncology, Department of Women and Children's Health and Public Health, Fondazione Policlinico Gemelli IRCCS, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Colombo+N%22">Colombo N</searchLink>; MaNGO and European Institute of Oncology and University of Milan Bicocca, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Koch+H%22">Koch H</searchLink>; AGO Austria and Department of Obstetrics and Gynecology, Paracelsus Medical University, Salzburg, Austria.<br /><searchLink fieldCode="AU" term="%22Goffin+F%22">Goffin F</searchLink>; BGOG and CHU de Liège, University of Liège, Liège, Belgium.<br /><searchLink fieldCode="AU" term="%22González-Martin+A%22">González-Martin A</searchLink>; GEICO and Medical Oncology Department, Clínica Universidad de Navarra, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Ottevanger+PB%22">Ottevanger PB</searchLink>; DGOG and Department of Medical Oncology, Radboud University Medical Centre, Nijmegen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Baumann+K%22">Baumann K</searchLink>; AGO and Department of Gynecology, Klinikum der Stadt Ludwigshafen GmbH, Ludwigshafen, Germany.<br /><searchLink fieldCode="AU" term="%22Bjørge+L%22">Bjørge L</searchLink>; NSGO and Department of Gynecology, Haukeland Universitetssykehus, Bergen, Norway.; Center for Cancer Biomarkers CCBIO, Department of Clinical Science, University of Bergen, Bergen, Norway.<br /><searchLink fieldCode="AU" term="%22Lesoin+A%22">Lesoin A</searchLink>; GINECO and Department of Gynecologic Cancer and Medical Oncology, Centre Oscar Lambret, Lille, France.<br /><searchLink fieldCode="AU" term="%22Burges+A%22">Burges A</searchLink>; AGO and Department of Obstetrics and Gynecology, University Hospital, LMU Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Rosenberg+P%22">Rosenberg P</searchLink>; NSGO and Department of Oncology, University Hospital Linköping, Linköping, Sweden.<br /><searchLink fieldCode="AU" term="%22Gropp-Meier+M%22">Gropp-Meier M</searchLink>; AGO and Department of Gynecology and Obstetrics, Oberschwabenklinik, Krankenhaus St. Elisabeth, Ravensburg, Germany.<br /><searchLink fieldCode="AU" term="%22Harrela+M%22">Harrela M</searchLink>; NSGO and Department of Gynoncology and Gynecology and Obstetrics, Kymenlaakso Central Hospital, Kotka, Finland.<br /><searchLink fieldCode="AU" term="%22Harter+P%22">Harter P</searchLink>; AGO and Department of Gynecology and Gynecologic Oncology, Kliniken Essen Mitte, Essen, Germany.<br /><searchLink fieldCode="AU" term="%22Frenel+JS%22">Frenel JS</searchLink>; GINECO and Centre René Gauducheau, Institut de Cancerologie de l'Ouest, Saint Herblain, France.<br /><searchLink fieldCode="AU" term="%22Minarik+T%22">Minarik T</searchLink>; NSGO and National Institute of Oncology, Bratislava, Slovakia.<br /><searchLink fieldCode="AU" term="%22Pisano+C%22">Pisano C</searchLink>; MITO and Department of Uro-Gynecologic Oncology, Istituto Nazionale per Io Studio e la Cura dei Tumori 'Fondazione G. Pascale' IRCCS, Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Hasenburg+A%22">Hasenburg A</searchLink>; AGO and Department of Obstetrics and Gynecology, University Medical Center, Mainz, Germany.<br /><searchLink fieldCode="AU" term="%22Merger+M%22">Merger M</searchLink>; Oncology Medicine, Boehringer Ingelheim International GmbH, Biberach, Germany.<br /><searchLink fieldCode="AU" term="%22du+Bois+A%22">du Bois A</searchLink>; AGO and Department of Gynecology and Gynecologic Oncology, Kliniken Essen Mitte, Essen, Germany.
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  Data: <searchLink fieldCode="CA" term="%22AGO+Study+Group-led+GCIG%2FENGOT+Intergroup+Consortium%22">AGO Study Group-led GCIG/ENGOT Intergroup Consortium</searchLink>
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  Data: <searchLink fieldCode="JN" term="%220042124%22">International journal of cancer</searchLink> [Int J Cancer] 2020 Jan 15; Vol. 146 (2), pp. 439-448. <i>Date of Electronic Publication: </i>2019 Sep 06.
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  Data: Clinical Trial, Phase III; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Wiley-Liss%22">Wiley-Liss </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>0042124 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1097-0215 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200207136%22">00207136 </searchLink><i>NLM ISO Abbreviation: </i>Int J Cancer <i>Subsets: </i>MEDLINE
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