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Metabolomic profiling reveals salivary hypotaurine as a potential early detection marker for medication-related osteonecrosis of the jaw.

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Title: Metabolomic profiling reveals salivary hypotaurine as a potential early detection marker for medication-related osteonecrosis of the jaw.
Authors: Yatsuoka W; Dental Division, National Cancer Center Hospital, Tsukiji, Chuo-ku, Japan.; Course of Advanced Clinical Research of Cancer, Juntendo University Graduate School of Medicine, Hongo, Bunkyo-ku, Tokyo, Japan., Ueno T; Dental Division, National Cancer Center Hospital, Tsukiji, Chuo-ku, Japan., Miyano K; Division of Cancer Pathophysiology, National Cancer Center Research Institute, Tsukiji, Chuo-ku, Japan., Uezono Y; Division of Cancer Pathophysiology, National Cancer Center Research Institute, Tsukiji, Chuo-ku, Japan.; Division of Supportive Care Research, Exploratory Oncology Research and Clinical Trial Center, National Cancer Center, Tsukiji, Chuo-ku, Japan.; Innovation Center for Supportive, Palliative and Psychosocial Care, National Cancer Center Hospital, Tsukiji, Chuo-ku, Japan., Enomoto A; Institute for Advanced Biosciences, Keio University, Tsuruoka City, Yamagata, Japan., Kaneko M; Institute for Advanced Biosciences, Keio University, Tsuruoka City, Yamagata, Japan., Ota S; Institute for Advanced Biosciences, Keio University, Tsuruoka City, Yamagata, Japan., Soga T; Institute for Advanced Biosciences, Keio University, Tsuruoka City, Yamagata, Japan., Sugimoto M; Institute for Advanced Biosciences, Keio University, Tsuruoka City, Yamagata, Japan.; Research and Development Center for Minimally Invasive Therapies Health Promotion and Preemptive Medicine, Tokyo Medical University, Shinjuku, Japan., Ushijima T; Course of Advanced Clinical Research of Cancer, Juntendo University Graduate School of Medicine, Hongo, Bunkyo-ku, Tokyo, Japan.; Division of Epigenomics, National Cancer Center Research Institute, Tsukiji, Chuo-ku, Japan.
Source: PloS one [PLoS One] 2019 Aug 12; Vol. 14 (8), pp. e0220712. Date of Electronic Publication: 2019 Aug 12 (Print Publication: 2019).
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Metabolomic profiling reveals salivary hypotaurine as a potential early detection marker for medication-related osteonecrosis of the jaw.
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  Data: <searchLink fieldCode="AU" term="%22Yatsuoka+W%22">Yatsuoka W</searchLink>; Dental Division, National Cancer Center Hospital, Tsukiji, Chuo-ku, Japan.; Course of Advanced Clinical Research of Cancer, Juntendo University Graduate School of Medicine, Hongo, Bunkyo-ku, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Ueno+T%22">Ueno T</searchLink>; Dental Division, National Cancer Center Hospital, Tsukiji, Chuo-ku, Japan.<br /><searchLink fieldCode="AU" term="%22Miyano+K%22">Miyano K</searchLink>; Division of Cancer Pathophysiology, National Cancer Center Research Institute, Tsukiji, Chuo-ku, Japan.<br /><searchLink fieldCode="AU" term="%22Uezono+Y%22">Uezono Y</searchLink>; Division of Cancer Pathophysiology, National Cancer Center Research Institute, Tsukiji, Chuo-ku, Japan.; Division of Supportive Care Research, Exploratory Oncology Research and Clinical Trial Center, National Cancer Center, Tsukiji, Chuo-ku, Japan.; Innovation Center for Supportive, Palliative and Psychosocial Care, National Cancer Center Hospital, Tsukiji, Chuo-ku, Japan.<br /><searchLink fieldCode="AU" term="%22Enomoto+A%22">Enomoto A</searchLink>; Institute for Advanced Biosciences, Keio University, Tsuruoka City, Yamagata, Japan.<br /><searchLink fieldCode="AU" term="%22Kaneko+M%22">Kaneko M</searchLink>; Institute for Advanced Biosciences, Keio University, Tsuruoka City, Yamagata, Japan.<br /><searchLink fieldCode="AU" term="%22Ota+S%22">Ota S</searchLink>; Institute for Advanced Biosciences, Keio University, Tsuruoka City, Yamagata, Japan.<br /><searchLink fieldCode="AU" term="%22Soga+T%22">Soga T</searchLink>; Institute for Advanced Biosciences, Keio University, Tsuruoka City, Yamagata, Japan.<br /><searchLink fieldCode="AU" term="%22Sugimoto+M%22">Sugimoto M</searchLink>; Institute for Advanced Biosciences, Keio University, Tsuruoka City, Yamagata, Japan.; Research and Development Center for Minimally Invasive Therapies Health Promotion and Preemptive Medicine, Tokyo Medical University, Shinjuku, Japan.<br /><searchLink fieldCode="AU" term="%22Ushijima+T%22">Ushijima T</searchLink>; Course of Advanced Clinical Research of Cancer, Juntendo University Graduate School of Medicine, Hongo, Bunkyo-ku, Tokyo, Japan.; Division of Epigenomics, National Cancer Center Research Institute, Tsukiji, Chuo-ku, Japan.
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  Data: <searchLink fieldCode="JN" term="%22101285081%22">PloS one</searchLink> [PLoS One] 2019 Aug 12; Vol. 14 (8), pp. e0220712. <i>Date of Electronic Publication: </i>2019 Aug 12 (<i>Print Publication: </i>2019).
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