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Effect of Linker Stereochemistry on the Activity of Indolinobenzodiazepine Containing Antibody-Drug Conjugates (ADCs).

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Title: Effect of Linker Stereochemistry on the Activity of Indolinobenzodiazepine Containing Antibody-Drug Conjugates (ADCs).
Authors: Reid EE; ImmunoGen, Inc., 830 Winter Street, Waltham, Massachusetts 02451, United States., Archer KE; ImmunoGen, Inc., 830 Winter Street, Waltham, Massachusetts 02451, United States., Shizuka M; ImmunoGen, Inc., 830 Winter Street, Waltham, Massachusetts 02451, United States., Wilhelm A; ImmunoGen, Inc., 830 Winter Street, Waltham, Massachusetts 02451, United States., Yoder NC; ImmunoGen, Inc., 830 Winter Street, Waltham, Massachusetts 02451, United States., Bai C; ImmunoGen, Inc., 830 Winter Street, Waltham, Massachusetts 02451, United States., Fishkin NE; ImmunoGen, Inc., 830 Winter Street, Waltham, Massachusetts 02451, United States., Harris L; ImmunoGen, Inc., 830 Winter Street, Waltham, Massachusetts 02451, United States., Maloney EK; ImmunoGen, Inc., 830 Winter Street, Waltham, Massachusetts 02451, United States., Salomon P; ImmunoGen, Inc., 830 Winter Street, Waltham, Massachusetts 02451, United States., Hong E; ImmunoGen, Inc., 830 Winter Street, Waltham, Massachusetts 02451, United States., Wu R; ImmunoGen, Inc., 830 Winter Street, Waltham, Massachusetts 02451, United States., Ab O; ImmunoGen, Inc., 830 Winter Street, Waltham, Massachusetts 02451, United States., Jin S; ImmunoGen, Inc., 830 Winter Street, Waltham, Massachusetts 02451, United States., Lai KC; ImmunoGen, Inc., 830 Winter Street, Waltham, Massachusetts 02451, United States., Sikka S; ImmunoGen, Inc., 830 Winter Street, Waltham, Massachusetts 02451, United States., Chari RVJ; ImmunoGen, Inc., 830 Winter Street, Waltham, Massachusetts 02451, United States., Miller ML; ImmunoGen, Inc., 830 Winter Street, Waltham, Massachusetts 02451, United States.
Source: ACS medicinal chemistry letters [ACS Med Chem Lett] 2019 Jul 10; Vol. 10 (8), pp. 1193-1197. Date of Electronic Publication: 2019 Jul 10 (Print Publication: 2019).
Publication Type: Journal Article
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101521073 Publication Model: eCollection Cited Medium: Print ISSN: 1948-5875 (Print) Linking ISSN: 19485875 NLM ISO Abbreviation: ACS Med Chem Lett Subsets: PubMed not MEDLINE
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  Data: Effect of Linker Stereochemistry on the Activity of Indolinobenzodiazepine Containing Antibody-Drug Conjugates (ADCs).
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