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An anti-CRF antibody suppresses the HPA axis and reverses stress-induced phenotypes.

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Title: An anti-CRF antibody suppresses the HPA axis and reverses stress-induced phenotypes.
Authors: Futch HS; McKnight Brain Institute, Center for Translational Research in Neurodegenerative Disease, Department of Neuroscience and Neurology, College of Medicine, University of Florida, Gainesville, FL., McFarland KN; McKnight Brain Institute, Center for Translational Research in Neurodegenerative Disease, Department of Neuroscience and Neurology, College of Medicine, University of Florida, Gainesville, FL., Moore BD; McKnight Brain Institute, Center for Translational Research in Neurodegenerative Disease, Department of Neuroscience and Neurology, College of Medicine, University of Florida, Gainesville, FL., Kuhn MZ; McKnight Brain Institute, Center for Translational Research in Neurodegenerative Disease, Department of Neuroscience and Neurology, College of Medicine, University of Florida, Gainesville, FL., Giasson BI; McKnight Brain Institute, Center for Translational Research in Neurodegenerative Disease, Department of Neuroscience and Neurology, College of Medicine, University of Florida, Gainesville, FL., Ladd TB; McKnight Brain Institute, Center for Translational Research in Neurodegenerative Disease, Department of Neuroscience and Neurology, College of Medicine, University of Florida, Gainesville, FL., Scott KA; McKnight Brain Institute, Department of Pharmacodynamics, College of Pharmacy, University of Florida, Gainesville, FL., Shapiro MR; Diabetes Institute, Department of Pathology, Immunology and Laboratory Medicine, College of Medicine, University of Florida, Gainesville, FL., Nosacka RL; Department of Physical Therapy, College of Public Health and Health Professions, University of Florida, Gainesville, FL., Goodwin MS; McKnight Brain Institute, Center for Translational Research in Neurodegenerative Disease, Department of Neuroscience and Neurology, College of Medicine, University of Florida, Gainesville, FL., Ran Y; McKnight Brain Institute, Center for Translational Research in Neurodegenerative Disease, Department of Neuroscience and Neurology, College of Medicine, University of Florida, Gainesville, FL., Cruz PE; McKnight Brain Institute, Center for Translational Research in Neurodegenerative Disease, Department of Neuroscience and Neurology, College of Medicine, University of Florida, Gainesville, FL., Ryu DH; McKnight Brain Institute, Center for Translational Research in Neurodegenerative Disease, Department of Neuroscience and Neurology, College of Medicine, University of Florida, Gainesville, FL., Croft CL; McKnight Brain Institute, Center for Translational Research in Neurodegenerative Disease, Department of Neuroscience and Neurology, College of Medicine, University of Florida, Gainesville, FL., Levites Y; McKnight Brain Institute, Center for Translational Research in Neurodegenerative Disease, Department of Neuroscience and Neurology, College of Medicine, University of Florida, Gainesville, FL., Janus C; McKnight Brain Institute, Center for Translational Research in Neurodegenerative Disease, Department of Neuroscience and Neurology, College of Medicine, University of Florida, Gainesville, FL., Chakrabarty P; McKnight Brain Institute, Center for Translational Research in Neurodegenerative Disease, Department of Neuroscience and Neurology, College of Medicine, University of Florida, Gainesville, FL., Judge AR; Department of Physical Therapy, College of Public Health and Health Professions, University of Florida, Gainesville, FL., Brusko TM; Diabetes Institute, Department of Pathology, Immunology and Laboratory Medicine, College of Medicine, University of Florida, Gainesville, FL., de Kloet AD; McKnight Brain Institute, Department of Pharmacodynamics, College of Pharmacy, University of Florida, Gainesville, FL., Krause EG; McKnight Brain Institute, Department of Physiology and Functional Genomics, College of Medicine, University of Florida, Gainesville, FL., Golde TE; McKnight Brain Institute, Center for Translational Research in Neurodegenerative Disease, Department of Neuroscience and Neurology, College of Medicine, University of Florida, Gainesville, FL tgolde@ufl.edu.
Source: The Journal of experimental medicine [J Exp Med] 2019 Nov 04; Vol. 216 (11), pp. 2479-2491. Date of Electronic Publication: 2019 Aug 29.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Rockefeller University Press Country of Publication: United States NLM ID: 2985109R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1540-9538 (Electronic) Linking ISSN: 00221007 NLM ISO Abbreviation: J Exp Med Subsets: MEDLINE
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  Data: An anti-CRF antibody suppresses the HPA axis and reverses stress-induced phenotypes.
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  Data: <searchLink fieldCode="AU" term="%22Futch+HS%22">Futch HS</searchLink>; McKnight Brain Institute, Center for Translational Research in Neurodegenerative Disease, Department of Neuroscience and Neurology, College of Medicine, University of Florida, Gainesville, FL.<br /><searchLink fieldCode="AU" term="%22McFarland+KN%22">McFarland KN</searchLink>; McKnight Brain Institute, Center for Translational Research in Neurodegenerative Disease, Department of Neuroscience and Neurology, College of Medicine, University of Florida, Gainesville, FL.<br /><searchLink fieldCode="AU" term="%22Moore+BD%22">Moore BD</searchLink>; McKnight Brain Institute, Center for Translational Research in Neurodegenerative Disease, Department of Neuroscience and Neurology, College of Medicine, University of Florida, Gainesville, FL.<br /><searchLink fieldCode="AU" term="%22Kuhn+MZ%22">Kuhn MZ</searchLink>; McKnight Brain Institute, Center for Translational Research in Neurodegenerative Disease, Department of Neuroscience and Neurology, College of Medicine, University of Florida, Gainesville, FL.<br /><searchLink fieldCode="AU" term="%22Giasson+BI%22">Giasson BI</searchLink>; McKnight Brain Institute, Center for Translational Research in Neurodegenerative Disease, Department of Neuroscience and Neurology, College of Medicine, University of Florida, Gainesville, FL.<br /><searchLink fieldCode="AU" term="%22Ladd+TB%22">Ladd TB</searchLink>; McKnight Brain Institute, Center for Translational Research in Neurodegenerative Disease, Department of Neuroscience and Neurology, College of Medicine, University of Florida, Gainesville, FL.<br /><searchLink fieldCode="AU" term="%22Scott+KA%22">Scott KA</searchLink>; McKnight Brain Institute, Department of Pharmacodynamics, College of Pharmacy, University of Florida, Gainesville, FL.<br /><searchLink fieldCode="AU" term="%22Shapiro+MR%22">Shapiro MR</searchLink>; Diabetes Institute, Department of Pathology, Immunology and Laboratory Medicine, College of Medicine, University of Florida, Gainesville, FL.<br /><searchLink fieldCode="AU" term="%22Nosacka+RL%22">Nosacka RL</searchLink>; Department of Physical Therapy, College of Public Health and Health Professions, University of Florida, Gainesville, FL.<br /><searchLink fieldCode="AU" term="%22Goodwin+MS%22">Goodwin MS</searchLink>; McKnight Brain Institute, Center for Translational Research in Neurodegenerative Disease, Department of Neuroscience and Neurology, College of Medicine, University of Florida, Gainesville, FL.<br /><searchLink fieldCode="AU" term="%22Ran+Y%22">Ran Y</searchLink>; McKnight Brain Institute, Center for Translational Research in Neurodegenerative Disease, Department of Neuroscience and Neurology, College of Medicine, University of Florida, Gainesville, FL.<br /><searchLink fieldCode="AU" term="%22Cruz+PE%22">Cruz PE</searchLink>; McKnight Brain Institute, Center for Translational Research in Neurodegenerative Disease, Department of Neuroscience and Neurology, College of Medicine, University of Florida, Gainesville, FL.<br /><searchLink fieldCode="AU" term="%22Ryu+DH%22">Ryu DH</searchLink>; McKnight Brain Institute, Center for Translational Research in Neurodegenerative Disease, Department of Neuroscience and Neurology, College of Medicine, University of Florida, Gainesville, FL.<br /><searchLink fieldCode="AU" term="%22Croft+CL%22">Croft CL</searchLink>; McKnight Brain Institute, Center for Translational Research in Neurodegenerative Disease, Department of Neuroscience and Neurology, College of Medicine, University of Florida, Gainesville, FL.<br /><searchLink fieldCode="AU" term="%22Levites+Y%22">Levites Y</searchLink>; McKnight Brain Institute, Center for Translational Research in Neurodegenerative Disease, Department of Neuroscience and Neurology, College of Medicine, University of Florida, Gainesville, FL.<br /><searchLink fieldCode="AU" term="%22Janus+C%22">Janus C</searchLink>; McKnight Brain Institute, Center for Translational Research in Neurodegenerative Disease, Department of Neuroscience and Neurology, College of Medicine, University of Florida, Gainesville, FL.<br /><searchLink fieldCode="AU" term="%22Chakrabarty+P%22">Chakrabarty P</searchLink>; McKnight Brain Institute, Center for Translational Research in Neurodegenerative Disease, Department of Neuroscience and Neurology, College of Medicine, University of Florida, Gainesville, FL.<br /><searchLink fieldCode="AU" term="%22Judge+AR%22">Judge AR</searchLink>; Department of Physical Therapy, College of Public Health and Health Professions, University of Florida, Gainesville, FL.<br /><searchLink fieldCode="AU" term="%22Brusko+TM%22">Brusko TM</searchLink>; Diabetes Institute, Department of Pathology, Immunology and Laboratory Medicine, College of Medicine, University of Florida, Gainesville, FL.<br /><searchLink fieldCode="AU" term="%22de+Kloet+AD%22">de Kloet AD</searchLink>; McKnight Brain Institute, Department of Pharmacodynamics, College of Pharmacy, University of Florida, Gainesville, FL.<br /><searchLink fieldCode="AU" term="%22Krause+EG%22">Krause EG</searchLink>; McKnight Brain Institute, Department of Physiology and Functional Genomics, College of Medicine, University of Florida, Gainesville, FL.<br /><searchLink fieldCode="AU" term="%22Golde+TE%22">Golde TE</searchLink>; McKnight Brain Institute, Center for Translational Research in Neurodegenerative Disease, Department of Neuroscience and Neurology, College of Medicine, University of Florida, Gainesville, FL tgolde@ufl.edu.
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  Data: <searchLink fieldCode="JN" term="%222985109R%22">The Journal of experimental medicine</searchLink> [J Exp Med] 2019 Nov 04; Vol. 216 (11), pp. 2479-2491. <i>Date of Electronic Publication: </i>2019 Aug 29.
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