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Liquid versus tissue biopsy for detecting acquired resistance and tumor heterogeneity in gastrointestinal cancers.

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Title: Liquid versus tissue biopsy for detecting acquired resistance and tumor heterogeneity in gastrointestinal cancers.
Authors: Parikh AR; Cancer Center, Massachusetts General Hospital, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA., Leshchiner I; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Elagina L; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Goyal L; Cancer Center, Massachusetts General Hospital, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA., Levovitz C; IBM Research, Yorktown Heights, NY, USA., Siravegna G; Candiolo Cancer Institute, FPO-IRCCS, Turin, Italy.; Department of Oncology, University of Torino, Turin, Italy., Livitz D; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Rhrissorrakrai K; IBM Research, Yorktown Heights, NY, USA., Martin EE; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Van Seventer EE; Cancer Center, Massachusetts General Hospital, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA., Hanna M; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Slowik K; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Utro F; IBM Research, Yorktown Heights, NY, USA., Pinto CJ; Cancer Center, Massachusetts General Hospital, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA., Wong A; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Danysh BP; Broad Institute of MIT and Harvard, Cambridge, MA, USA., de la Cruz FF; Cancer Center, Massachusetts General Hospital, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA., Fetter IJ; Cancer Center, Massachusetts General Hospital, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA., Nadres B; Cancer Center, Massachusetts General Hospital, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA., Shahzade HA; Cancer Center, Massachusetts General Hospital, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA., Allen JN; Cancer Center, Massachusetts General Hospital, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA., Blaszkowsky LS; Cancer Center, Massachusetts General Hospital, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA., Clark JW; Cancer Center, Massachusetts General Hospital, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA., Giantonio B; Cancer Center, Massachusetts General Hospital, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA., Murphy JE; Cancer Center, Massachusetts General Hospital, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA., Nipp RD; Cancer Center, Massachusetts General Hospital, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA., Roeland E; Cancer Center, Massachusetts General Hospital, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA., Ryan DP; Cancer Center, Massachusetts General Hospital, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA., Weekes CD; Cancer Center, Massachusetts General Hospital, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA., Kwak EL; Cancer Center, Massachusetts General Hospital, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA., Faris JE; Cancer Center, Massachusetts General Hospital, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA., Wo JY; Cancer Center, Massachusetts General Hospital, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA., Aguet F; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Dey-Guha I; Cancer Center, Massachusetts General Hospital, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA., Hazar-Rethinam M; Cancer Center, Massachusetts General Hospital, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA., Dias-Santagata D; Cancer Center, Massachusetts General Hospital, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA., Ting DT; Cancer Center, Massachusetts General Hospital, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA., Zhu AX; Cancer Center, Massachusetts General Hospital, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA., Hong TS; Cancer Center, Massachusetts General Hospital, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA., Golub TR; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Dana-Farber Cancer Institute, Boston, MA, USA.; Howard Hughes Medical Institute, Boston, MA, USA., Iafrate AJ; Cancer Center, Massachusetts General Hospital, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA., Adalsteinsson VA; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Bardelli A; Candiolo Cancer Institute, FPO-IRCCS, Turin, Italy.; Department of Oncology, University of Torino, Turin, Italy., Parida L; IBM Research, Yorktown Heights, NY, USA., Juric D; Cancer Center, Massachusetts General Hospital, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA., Getz G; Cancer Center, Massachusetts General Hospital, Boston, MA, USA. gadgetz@broadinstitute.org.; Department of Medicine, Harvard Medical School, Boston, MA, USA. gadgetz@broadinstitute.org.; Broad Institute of MIT and Harvard, Cambridge, MA, USA. gadgetz@broadinstitute.org.; Department of Pathology, Massachusetts General Hospital, Boston, MA, USA. gadgetz@broadinstitute.org., Corcoran RB; Cancer Center, Massachusetts General Hospital, Boston, MA, USA. rbcorcoran@partners.org.; Department of Medicine, Harvard Medical School, Boston, MA, USA. rbcorcoran@partners.org.
Source: Nature medicine [Nat Med] 2019 Sep; Vol. 25 (9), pp. 1415-1421. Date of Electronic Publication: 2019 Sep 09.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Publishing Company Country of Publication: United States NLM ID: 9502015 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-170X (Electronic) Linking ISSN: 10788956 NLM ISO Abbreviation: Nat Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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