Benzothiazole-based compounds as potent endothelial lipase inhibitors.

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Title: Benzothiazole-based compounds as potent endothelial lipase inhibitors.
Authors: Meng W; Department of Discovery Chemistry, Bristol-Myers Squibb, Research and Development, PO Box 5400, Princeton, NJ 08543-5400, United States. Electronic address: wei.meng@bms.com., Adam LP; Department of Cardiovascular Diseases, Bristol-Myers Squibb, Research and Development, PO Box 5400, Princeton, NJ 08543-5400, United States., Behnia K; Department of Pharmaceutical Candidate Optimization, Bristol-Myers Squibb, Research and Development, PO Box 5400, Princeton, NJ 08543-5400, United States., Zhao L; Department of Cardiovascular Diseases, Bristol-Myers Squibb, Research and Development, PO Box 5400, Princeton, NJ 08543-5400, United States., Yang R; Department of Cardiovascular Diseases, Bristol-Myers Squibb, Research and Development, PO Box 5400, Princeton, NJ 08543-5400, United States., Kopcho LM; Department of Pharmaceutical Candidate Optimization, Bristol-Myers Squibb, Research and Development, PO Box 5400, Princeton, NJ 08543-5400, United States., Locke GA; Department of Pharmaceutical Candidate Optimization, Bristol-Myers Squibb, Research and Development, PO Box 5400, Princeton, NJ 08543-5400, United States., Taylor DS; Department of Cardiovascular Diseases, Bristol-Myers Squibb, Research and Development, PO Box 5400, Princeton, NJ 08543-5400, United States., Yin X; Department of Cardiovascular Diseases, Bristol-Myers Squibb, Research and Development, PO Box 5400, Princeton, NJ 08543-5400, United States., Wexler RR; Department of Discovery Chemistry, Bristol-Myers Squibb, Research and Development, PO Box 5400, Princeton, NJ 08543-5400, United States., Finlay H; Department of Discovery Chemistry, Bristol-Myers Squibb, Research and Development, PO Box 5400, Princeton, NJ 08543-5400, United States.
Source: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2019 Oct 15; Vol. 29 (20), pp. 126673. Date of Electronic Publication: 2019 Sep 06.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9107377 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-3405 (Electronic) Linking ISSN: 0960894X NLM ISO Abbreviation: Bioorg Med Chem Lett Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Benzothiazole-based compounds as potent endothelial lipase inhibitors.
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  Data: <searchLink fieldCode="AU" term="%22Meng+W%22">Meng W</searchLink>; Department of Discovery Chemistry, Bristol-Myers Squibb, Research and Development, PO Box 5400, Princeton, NJ 08543-5400, United States. Electronic address: wei.meng@bms.com.<br /><searchLink fieldCode="AU" term="%22Adam+LP%22">Adam LP</searchLink>; Department of Cardiovascular Diseases, Bristol-Myers Squibb, Research and Development, PO Box 5400, Princeton, NJ 08543-5400, United States.<br /><searchLink fieldCode="AU" term="%22Behnia+K%22">Behnia K</searchLink>; Department of Pharmaceutical Candidate Optimization, Bristol-Myers Squibb, Research and Development, PO Box 5400, Princeton, NJ 08543-5400, United States.<br /><searchLink fieldCode="AU" term="%22Zhao+L%22">Zhao L</searchLink>; Department of Cardiovascular Diseases, Bristol-Myers Squibb, Research and Development, PO Box 5400, Princeton, NJ 08543-5400, United States.<br /><searchLink fieldCode="AU" term="%22Yang+R%22">Yang R</searchLink>; Department of Cardiovascular Diseases, Bristol-Myers Squibb, Research and Development, PO Box 5400, Princeton, NJ 08543-5400, United States.<br /><searchLink fieldCode="AU" term="%22Kopcho+LM%22">Kopcho LM</searchLink>; Department of Pharmaceutical Candidate Optimization, Bristol-Myers Squibb, Research and Development, PO Box 5400, Princeton, NJ 08543-5400, United States.<br /><searchLink fieldCode="AU" term="%22Locke+GA%22">Locke GA</searchLink>; Department of Pharmaceutical Candidate Optimization, Bristol-Myers Squibb, Research and Development, PO Box 5400, Princeton, NJ 08543-5400, United States.<br /><searchLink fieldCode="AU" term="%22Taylor+DS%22">Taylor DS</searchLink>; Department of Cardiovascular Diseases, Bristol-Myers Squibb, Research and Development, PO Box 5400, Princeton, NJ 08543-5400, United States.<br /><searchLink fieldCode="AU" term="%22Yin+X%22">Yin X</searchLink>; Department of Cardiovascular Diseases, Bristol-Myers Squibb, Research and Development, PO Box 5400, Princeton, NJ 08543-5400, United States.<br /><searchLink fieldCode="AU" term="%22Wexler+RR%22">Wexler RR</searchLink>; Department of Discovery Chemistry, Bristol-Myers Squibb, Research and Development, PO Box 5400, Princeton, NJ 08543-5400, United States.<br /><searchLink fieldCode="AU" term="%22Finlay+H%22">Finlay H</searchLink>; Department of Discovery Chemistry, Bristol-Myers Squibb, Research and Development, PO Box 5400, Princeton, NJ 08543-5400, United States.
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  Data: <searchLink fieldCode="JN" term="%229107377%22">Bioorganic & medicinal chemistry letters</searchLink> [Bioorg Med Chem Lett] 2019 Oct 15; Vol. 29 (20), pp. 126673. <i>Date of Electronic Publication: </i>2019 Sep 06.
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              Text: 2019 Oct 15
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