View in EDS

Rapid Identification of Novel Allosteric PRC2 Inhibitors.

Saved in:
Bibliographic Details
Title: Rapid Identification of Novel Allosteric PRC2 Inhibitors.
Authors: Read JA; Structure and Biophysics, Discovery Sciences , R&D, AstraZeneca , Cambridge , CB4 0WG U.K., Tart J; Discovery Biology, Discovery Sciences , R&D, AstraZeneca , Cambridge , CB4 0WG U.K., Rawlins PB; Structure and Biophysics, Discovery Sciences , R&D, AstraZeneca , Cambridge , CB4 0WG U.K., Gregson C; Medicinal Chemistry , Oncology R&D, AstraZeneca , Cambridge , CB4 0WG U.K., Jones K; Hit Discovery, Discovery Sciences , R&D, AstraZeneca , Macclesfield , SK10 4TG U.K., Gao N; Mechanistic Biology and Profiling, Discovery Sciences , R&D, AstraZeneca , Waltham , Massachusetts 02451 , United States., Zhu X; Mechanistic Biology and Profiling, Discovery Sciences , R&D, AstraZeneca , Waltham , Massachusetts 02451 , United States., Tomlinson R; Discovery Biology, Discovery Sciences , R&D, AstraZeneca , Waltham , Massachusetts 02451 , United States., Code E; Mechanistic Biology and Profiling, Discovery Sciences , R&D, AstraZeneca , Waltham , Massachusetts 02451 , United States., Cheung T; Bioscience, Research and Early Development , Oncology R&D, AstraZeneca , Waltham , Massachusetts 02451 , United States., Chen H; Bioscience, Research and Early Development , Oncology R&D, AstraZeneca , Waltham , Massachusetts 02451 , United States., Kawatkar SP; Medicinal Chemistry , Oncology R&D, AstraZeneca , Waltham , Massachusetts 02451 , United States., Bloecher A; Bioscience, Research and Early Development , Oncology R&D, AstraZeneca , Waltham , Massachusetts 02451 , United States., Bagal S; Medicinal Chemistry , Oncology R&D, AstraZeneca , Cambridge , CB4 0WG U.K., O'Donovan DH; Medicinal Chemistry , Oncology R&D, AstraZeneca , Cambridge , CB4 0WG U.K., Robinson J; Mechanistic Biology and Profiling, Discovery Sciences , R&D, AstraZeneca , Cambridge , CB4 0WG U.K.
Source: ACS chemical biology [ACS Chem Biol] 2019 Oct 18; Vol. 14 (10), pp. 2134-2140. Date of Electronic Publication: 2019 Sep 23.
Publication Type: Journal Article
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101282906 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1554-8937 (Electronic) Linking ISSN: 15548929 NLM ISO Abbreviation: ACS Chem Biol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1554-8937
DOI:10.1021/acschembio.9b00468