Integrated paired-end enhancer profiling and whole-genome sequencing reveals recurrent CCNE1 and IGF2 enhancer hijacking in primary gastric adenocarcinoma.

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Title: Integrated paired-end enhancer profiling and whole-genome sequencing reveals recurrent CCNE1 and IGF2 enhancer hijacking in primary gastric adenocarcinoma.
Authors: Ooi WF; Cancer Therapeutics and Stratified Oncology, Genome Institute of Singapore, Singapore., Nargund AM; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore., Lim KJ; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore.; Centre for Computational Biology, Duke-NUS Medical School, Singapore., Zhang S; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore., Xing M; Cancer Therapeutics and Stratified Oncology, Genome Institute of Singapore, Singapore., Mandoli A; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore., Lim JQ; Lymphoma Genomic Translational Laboratory, National Cancer Centre Singapore, Singapore., Ho SWT; Cancer Science Institute of Singapore, National University of Singapore, Singapore., Guo Y; Computational and Systems Biology, Genome Institute of Singapore, Singapore., Yao X; Cancer Therapeutics and Stratified Oncology, Genome Institute of Singapore, Singapore., Lin SJ; Cancer Therapeutics and Stratified Oncology, Genome Institute of Singapore, Singapore., Nandi T; Cancer Therapeutics and Stratified Oncology, Genome Institute of Singapore, Singapore., Xu C; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore., Ong X; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore., Lee M; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore., Tan AL; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore., Lam YN; Cancer Therapeutics and Stratified Oncology, Genome Institute of Singapore, Singapore., Teo JX; SingHealth/Duke-NUS Institute of Precision Medicine, National Heart Centre, Singapore., Kaneda A; Department of Molecular Oncology, Chiba University, Chiba, Japan., White KP; Institute for Genomics and Systems Biology, University of Chicago and Argonne National Laboratory, Chicago, Illinois, USA.; Tempus Labs, Chicago, Illinois, USA., Lim WK; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore.; SingHealth/Duke-NUS Institute of Precision Medicine, National Heart Centre, Singapore., Rozen SG; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore.; Centre for Computational Biology, Duke-NUS Medical School, Singapore.; SingHealth/Duke-NUS Institute of Precision Medicine, National Heart Centre, Singapore., Teh BT; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore.; Cancer Science Institute of Singapore, National University of Singapore, Singapore.; SingHealth/Duke-NUS Institute of Precision Medicine, National Heart Centre, Singapore.; Laboratory of Cancer Epigenome, National Cancer Centre Singapore, Singapore., Li S; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore., Skanderup AJ; Computational and Systems Biology, Genome Institute of Singapore, Singapore., Tan P; Cancer Therapeutics and Stratified Oncology, Genome Institute of Singapore, Singapore gmstanp@duke-nus.edu.sg.; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore.; Cancer Science Institute of Singapore, National University of Singapore, Singapore.; SingHealth/Duke-NUS Institute of Precision Medicine, National Heart Centre, Singapore.
Source: Gut [Gut] 2020 Jun; Vol. 69 (6), pp. 1039-1052. Date of Electronic Publication: 2019 Sep 21.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: British Medical Assn Country of Publication: England NLM ID: 2985108R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1468-3288 (Electronic) Linking ISSN: 00175749 NLM ISO Abbreviation: Gut Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Integrated paired-end enhancer profiling and whole-genome sequencing reveals recurrent CCNE1 and IGF2 enhancer hijacking in primary gastric adenocarcinoma.
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  Data: <searchLink fieldCode="AU" term="%22Ooi+WF%22">Ooi WF</searchLink>; Cancer Therapeutics and Stratified Oncology, Genome Institute of Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Nargund+AM%22">Nargund AM</searchLink>; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore.<br /><searchLink fieldCode="AU" term="%22Lim+KJ%22">Lim KJ</searchLink>; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore.; Centre for Computational Biology, Duke-NUS Medical School, Singapore.<br /><searchLink fieldCode="AU" term="%22Zhang+S%22">Zhang S</searchLink>; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore.<br /><searchLink fieldCode="AU" term="%22Xing+M%22">Xing M</searchLink>; Cancer Therapeutics and Stratified Oncology, Genome Institute of Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Mandoli+A%22">Mandoli A</searchLink>; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore.<br /><searchLink fieldCode="AU" term="%22Lim+JQ%22">Lim JQ</searchLink>; Lymphoma Genomic Translational Laboratory, National Cancer Centre Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Ho+SWT%22">Ho SWT</searchLink>; Cancer Science Institute of Singapore, National University of Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Guo+Y%22">Guo Y</searchLink>; Computational and Systems Biology, Genome Institute of Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Yao+X%22">Yao X</searchLink>; Cancer Therapeutics and Stratified Oncology, Genome Institute of Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Lin+SJ%22">Lin SJ</searchLink>; Cancer Therapeutics and Stratified Oncology, Genome Institute of Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Nandi+T%22">Nandi T</searchLink>; Cancer Therapeutics and Stratified Oncology, Genome Institute of Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Xu+C%22">Xu C</searchLink>; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore.<br /><searchLink fieldCode="AU" term="%22Ong+X%22">Ong X</searchLink>; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore.<br /><searchLink fieldCode="AU" term="%22Lee+M%22">Lee M</searchLink>; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore.<br /><searchLink fieldCode="AU" term="%22Tan+AL%22">Tan AL</searchLink>; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore.<br /><searchLink fieldCode="AU" term="%22Lam+YN%22">Lam YN</searchLink>; Cancer Therapeutics and Stratified Oncology, Genome Institute of Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Teo+JX%22">Teo JX</searchLink>; SingHealth/Duke-NUS Institute of Precision Medicine, National Heart Centre, Singapore.<br /><searchLink fieldCode="AU" term="%22Kaneda+A%22">Kaneda A</searchLink>; Department of Molecular Oncology, Chiba University, Chiba, Japan.<br /><searchLink fieldCode="AU" term="%22White+KP%22">White KP</searchLink>; Institute for Genomics and Systems Biology, University of Chicago and Argonne National Laboratory, Chicago, Illinois, USA.; Tempus Labs, Chicago, Illinois, USA.<br /><searchLink fieldCode="AU" term="%22Lim+WK%22">Lim WK</searchLink>; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore.; SingHealth/Duke-NUS Institute of Precision Medicine, National Heart Centre, Singapore.<br /><searchLink fieldCode="AU" term="%22Rozen+SG%22">Rozen SG</searchLink>; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore.; Centre for Computational Biology, Duke-NUS Medical School, Singapore.; SingHealth/Duke-NUS Institute of Precision Medicine, National Heart Centre, Singapore.<br /><searchLink fieldCode="AU" term="%22Teh+BT%22">Teh BT</searchLink>; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore.; Cancer Science Institute of Singapore, National University of Singapore, Singapore.; SingHealth/Duke-NUS Institute of Precision Medicine, National Heart Centre, Singapore.; Laboratory of Cancer Epigenome, National Cancer Centre Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Li+S%22">Li S</searchLink>; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore.<br /><searchLink fieldCode="AU" term="%22Skanderup+AJ%22">Skanderup AJ</searchLink>; Computational and Systems Biology, Genome Institute of Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Tan+P%22">Tan P</searchLink>; Cancer Therapeutics and Stratified Oncology, Genome Institute of Singapore, Singapore gmstanp@duke-nus.edu.sg.; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore.; Cancer Science Institute of Singapore, National University of Singapore, Singapore.; SingHealth/Duke-NUS Institute of Precision Medicine, National Heart Centre, Singapore.
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  Data: <searchLink fieldCode="JN" term="%222985108R%22">Gut</searchLink> [Gut] 2020 Jun; Vol. 69 (6), pp. 1039-1052. <i>Date of Electronic Publication: </i>2019 Sep 21.
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        Value: 10.1136/gutjnl-2018-317612
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