Diversification and CXCR4-Dependent Establishment of the Bone Marrow B-1a Cell Pool Governs Atheroprotective IgM Production Linked to Human Coronary Atherosclerosis.

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Title: Diversification and CXCR4-Dependent Establishment of the Bone Marrow B-1a Cell Pool Governs Atheroprotective IgM Production Linked to Human Coronary Atherosclerosis.
Authors: Upadhye A; From the Cardiovascular Research Center (A.U., P.S., H.M.P., A.N., C.M., M.A.M., J.C.G, A.M.T., C.A.M.), University of Virginia, Charlottesville.; Department of Microbiology, Immunology, Cancer Biology (A.U., T.P.B.), University of Virginia, Charlottesville., Srikakulapu P; From the Cardiovascular Research Center (A.U., P.S., H.M.P., A.N., C.M., M.A.M., J.C.G, A.M.T., C.A.M.), University of Virginia, Charlottesville., Gonen A; Department of Medicine, University of California San Diego, La Jolla (A.G., S.H., S.T., J.L.W.)., Hendrikx S; Department of Medicine, University of California San Diego, La Jolla (A.G., S.H., S.T., J.L.W.)., Perry HM; From the Cardiovascular Research Center (A.U., P.S., H.M.P., A.N., C.M., M.A.M., J.C.G, A.M.T., C.A.M.), University of Virginia, Charlottesville., Nguyen A; From the Cardiovascular Research Center (A.U., P.S., H.M.P., A.N., C.M., M.A.M., J.C.G, A.M.T., C.A.M.), University of Virginia, Charlottesville., McSkimming C; From the Cardiovascular Research Center (A.U., P.S., H.M.P., A.N., C.M., M.A.M., J.C.G, A.M.T., C.A.M.), University of Virginia, Charlottesville., Marshall MA; From the Cardiovascular Research Center (A.U., P.S., H.M.P., A.N., C.M., M.A.M., J.C.G, A.M.T., C.A.M.), University of Virginia, Charlottesville., Garmey JC; From the Cardiovascular Research Center (A.U., P.S., H.M.P., A.N., C.M., M.A.M., J.C.G, A.M.T., C.A.M.), University of Virginia, Charlottesville., Taylor AM; From the Cardiovascular Research Center (A.U., P.S., H.M.P., A.N., C.M., M.A.M., J.C.G, A.M.T., C.A.M.), University of Virginia, Charlottesville.; Department of Medicine (A.M.T., C.A.M.), University of Virginia, Charlottesville., Bender TP; Department of Microbiology, Immunology, Cancer Biology (A.U., T.P.B.), University of Virginia, Charlottesville.; Beirne B. Carter Center for Immunology Research (T.P.B., C.A.M.), University of Virginia, Charlottesville., Tsimikas S; Department of Medicine, University of California San Diego, La Jolla (A.G., S.H., S.T., J.L.W.)., Holodick NE; Center for Immunobiology and Department of Biomedical Sciences, Western Michigan University Homer Stryker M.D. School of Medicine, Kalamazoo MI (N.E.H., T.L.R.)., Rothstein TL; Center for Immunobiology and Department of Biomedical Sciences, Western Michigan University Homer Stryker M.D. School of Medicine, Kalamazoo MI (N.E.H., T.L.R.)., Witztum JL; Department of Medicine, University of California San Diego, La Jolla (A.G., S.H., S.T., J.L.W.)., McNamara CA; From the Cardiovascular Research Center (A.U., P.S., H.M.P., A.N., C.M., M.A.M., J.C.G, A.M.T., C.A.M.), University of Virginia, Charlottesville.; Beirne B. Carter Center for Immunology Research (T.P.B., C.A.M.), University of Virginia, Charlottesville.; Department of Medicine (A.M.T., C.A.M.), University of Virginia, Charlottesville.
Source: Circulation research [Circ Res] 2019 Oct 25; Vol. 125 (10), pp. e55-e70. Date of Electronic Publication: 2019 Sep 24.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 0047103 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1524-4571 (Electronic) Linking ISSN: 00097330 NLM ISO Abbreviation: Circ Res Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1524-4571
DOI:10.1161/CIRCRESAHA.119.315786