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Small molecule inhibition of lysine-specific demethylase 1 (LSD1) and histone deacetylase (HDAC) alone and in combination in Ewing sarcoma cell lines.

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Title: Small molecule inhibition of lysine-specific demethylase 1 (LSD1) and histone deacetylase (HDAC) alone and in combination in Ewing sarcoma cell lines.
Authors: Welch D; Sunshine Lab, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America.; Translational Research Core, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America., Kahen E; Sunshine Lab, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America.; Translational Research Core, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America., Fridley B; Department of Biostatistics, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America., Brohl AS; Sarcoma Department, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America.; Chemical Biology and Molecular Medicine Program, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America., Cubitt CL; Translational Research Core, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America., Reed DR; Sunshine Lab, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America.; Sarcoma Department, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America.; Chemical Biology and Molecular Medicine Program, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America.; Adolescent and Young Adult Program, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America.
Source: PloS one [PLoS One] 2019 Sep 24; Vol. 14 (9), pp. e0222228. Date of Electronic Publication: 2019 Sep 24 (Print Publication: 2019).
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Small molecule inhibition of lysine-specific demethylase 1 (LSD1) and histone deacetylase (HDAC) alone and in combination in Ewing sarcoma cell lines.
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  Data: <searchLink fieldCode="AU" term="%22Welch+D%22">Welch D</searchLink>; Sunshine Lab, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America.; Translational Research Core, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America.<br /><searchLink fieldCode="AU" term="%22Kahen+E%22">Kahen E</searchLink>; Sunshine Lab, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America.; Translational Research Core, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America.<br /><searchLink fieldCode="AU" term="%22Fridley+B%22">Fridley B</searchLink>; Department of Biostatistics, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America.<br /><searchLink fieldCode="AU" term="%22Brohl+AS%22">Brohl AS</searchLink>; Sarcoma Department, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America.; Chemical Biology and Molecular Medicine Program, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America.<br /><searchLink fieldCode="AU" term="%22Cubitt+CL%22">Cubitt CL</searchLink>; Translational Research Core, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America.<br /><searchLink fieldCode="AU" term="%22Reed+DR%22">Reed DR</searchLink>; Sunshine Lab, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America.; Sarcoma Department, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America.; Chemical Biology and Molecular Medicine Program, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America.; Adolescent and Young Adult Program, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America.
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  Data: <searchLink fieldCode="JN" term="%22101285081%22">PloS one</searchLink> [PLoS One] 2019 Sep 24; Vol. 14 (9), pp. e0222228. <i>Date of Electronic Publication: </i>2019 Sep 24 (<i>Print Publication: </i>2019).
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        Value: 10.1371/journal.pone.0222228
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