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Excitatory GABAergic signalling is associated with benzodiazepine resistance in status epilepticus.

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Title: Excitatory GABAergic signalling is associated with benzodiazepine resistance in status epilepticus.
Authors: Burman RJ; Division of Cell Biology, Department of Human Biology, Neuroscience Institute and Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.; Department of Paediatric Neurology, Red Cross War Memorial Children's Hospital, Neuroscience Institute, University of Cape Town, Cape Town, South Africa.; Department of Pharmacology, University of Oxford, Oxford, UK., Selfe JS; Division of Cell Biology, Department of Human Biology, Neuroscience Institute and Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa., Lee JH; Division of Cell Biology, Department of Human Biology, Neuroscience Institute and Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa., van den Berg M; Division of Cell Biology, Department of Human Biology, Neuroscience Institute and Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa., Calin A; Department of Pharmacology, University of Oxford, Oxford, UK., Codadu NK; Institute of Neuroscience, Medical School, Framlington Place, Newcastle upon Tyne, NE24HH, UK., Wright R; Department of Pharmacology, University of Oxford, Oxford, UK., Newey SE; Department of Pharmacology, University of Oxford, Oxford, UK., Parrish RR; Institute of Neuroscience, Medical School, Framlington Place, Newcastle upon Tyne, NE24HH, UK., Katz AA; Division of Medical Biochemistry, Department of Integrated Biomedical Sciences and Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa., Wilmshurst JM; Department of Paediatric Neurology, Red Cross War Memorial Children's Hospital, Neuroscience Institute, University of Cape Town, Cape Town, South Africa., Akerman CJ; Department of Pharmacology, University of Oxford, Oxford, UK., Trevelyan AJ; Institute of Neuroscience, Medical School, Framlington Place, Newcastle upon Tyne, NE24HH, UK., Raimondo JV; Division of Cell Biology, Department of Human Biology, Neuroscience Institute and Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.
Source: Brain : a journal of neurology [Brain] 2019 Nov 01; Vol. 142 (11), pp. 3482-3501.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 0372537 Publication Model: Print Cited Medium: Internet ISSN: 1460-2156 (Electronic) Linking ISSN: 00068950 NLM ISO Abbreviation: Brain Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Burman+RJ%22">Burman RJ</searchLink>; Division of Cell Biology, Department of Human Biology, Neuroscience Institute and Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.; Department of Paediatric Neurology, Red Cross War Memorial Children's Hospital, Neuroscience Institute, University of Cape Town, Cape Town, South Africa.; Department of Pharmacology, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Selfe+JS%22">Selfe JS</searchLink>; Division of Cell Biology, Department of Human Biology, Neuroscience Institute and Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.<br /><searchLink fieldCode="AU" term="%22Lee+JH%22">Lee JH</searchLink>; Division of Cell Biology, Department of Human Biology, Neuroscience Institute and Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.<br /><searchLink fieldCode="AU" term="%22van+den+Berg+M%22">van den Berg M</searchLink>; Division of Cell Biology, Department of Human Biology, Neuroscience Institute and Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.<br /><searchLink fieldCode="AU" term="%22Calin+A%22">Calin A</searchLink>; Department of Pharmacology, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Codadu+NK%22">Codadu NK</searchLink>; Institute of Neuroscience, Medical School, Framlington Place, Newcastle upon Tyne, NE24HH, UK.<br /><searchLink fieldCode="AU" term="%22Wright+R%22">Wright R</searchLink>; Department of Pharmacology, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Newey+SE%22">Newey SE</searchLink>; Department of Pharmacology, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Parrish+RR%22">Parrish RR</searchLink>; Institute of Neuroscience, Medical School, Framlington Place, Newcastle upon Tyne, NE24HH, UK.<br /><searchLink fieldCode="AU" term="%22Katz+AA%22">Katz AA</searchLink>; Division of Medical Biochemistry, Department of Integrated Biomedical Sciences and Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.<br /><searchLink fieldCode="AU" term="%22Wilmshurst+JM%22">Wilmshurst JM</searchLink>; Department of Paediatric Neurology, Red Cross War Memorial Children's Hospital, Neuroscience Institute, University of Cape Town, Cape Town, South Africa.<br /><searchLink fieldCode="AU" term="%22Akerman+CJ%22">Akerman CJ</searchLink>; Department of Pharmacology, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Trevelyan+AJ%22">Trevelyan AJ</searchLink>; Institute of Neuroscience, Medical School, Framlington Place, Newcastle upon Tyne, NE24HH, UK.<br /><searchLink fieldCode="AU" term="%22Raimondo+JV%22">Raimondo JV</searchLink>; Division of Cell Biology, Department of Human Biology, Neuroscience Institute and Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.
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