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A conditional inducible JAK2V617F transgenic mouse model reveals myeloproliferative disease that is reversible upon switching off transgene expression.

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Title: A conditional inducible JAK2V617F transgenic mouse model reveals myeloproliferative disease that is reversible upon switching off transgene expression.
Authors: Chapeau EA; Disease Area Oncology, Novartis Institutes for BioMedical Research, Basel, Switzerland., Mandon E; Disease Area Oncology, Novartis Institutes for BioMedical Research, Basel, Switzerland., Gill J; Friedrich Miescher Institute for Biomedical Research, Basel, Switzerland., Romanet V; Disease Area Oncology, Novartis Institutes for BioMedical Research, Basel, Switzerland., Ebel N; Disease Area Oncology, Novartis Institutes for BioMedical Research, Basel, Switzerland., Powajbo V; Disease Area Oncology, Novartis Institutes for BioMedical Research, Basel, Switzerland., Andraos-Rey R; Disease Area Oncology, Novartis Institutes for BioMedical Research, Basel, Switzerland., Qian Z; Disease Area Oncology, Novartis Institutes for BioMedical Research, Basel, Switzerland., Kininis M; Disease Area Oncology, Novartis Institutes for BioMedical Research, Basel, Switzerland., Zumstein-Mecker S; Disease Area Oncology, Novartis Institutes for BioMedical Research, Basel, Switzerland., Ito M; Disease Area Oncology, Novartis Institutes for BioMedical Research, Basel, Switzerland., Hynes NE; Friedrich Miescher Institute for Biomedical Research, Basel, Switzerland., Tiedt R; Disease Area Oncology, Novartis Institutes for BioMedical Research, Basel, Switzerland., Hofmann F; Disease Area Oncology, Novartis Institutes for BioMedical Research, Basel, Switzerland., Eshkind L; Institute for Translational Immunology and Research Center for Immunotherapy, University Medical Center, Johannes Gutenberg University, Mainz, Germany., Bockamp E; Institute for Translational Immunology and Research Center for Immunotherapy, University Medical Center, Johannes Gutenberg University, Mainz, Germany., Kinzel B; Chemical Biology and Therapeutics, Novartis Institutes for BioMedical Research, Basel, Switzerland., Mueller M; Chemical Biology and Therapeutics, Novartis Institutes for BioMedical Research, Basel, Switzerland., Murakami M; Disease Area Oncology, Novartis Institutes for BioMedical Research, Basel, Switzerland., Baffert F; Disease Area Oncology, Novartis Institutes for BioMedical Research, Basel, Switzerland., Radimerski T; Disease Area Oncology, Novartis Institutes for BioMedical Research, Basel, Switzerland.
Source: PloS one [PLoS One] 2019 Oct 10; Vol. 14 (10), pp. e0221635. Date of Electronic Publication: 2019 Oct 10 (Print Publication: 2019).
Publication Type: Journal Article
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: A conditional inducible JAK2V617F transgenic mouse model reveals myeloproliferative disease that is reversible upon switching off transgene expression.
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  Data: <searchLink fieldCode="AU" term="%22Chapeau+EA%22">Chapeau EA</searchLink>; Disease Area Oncology, Novartis Institutes for BioMedical Research, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Mandon+E%22">Mandon E</searchLink>; Disease Area Oncology, Novartis Institutes for BioMedical Research, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Gill+J%22">Gill J</searchLink>; Friedrich Miescher Institute for Biomedical Research, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Romanet+V%22">Romanet V</searchLink>; Disease Area Oncology, Novartis Institutes for BioMedical Research, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Ebel+N%22">Ebel N</searchLink>; Disease Area Oncology, Novartis Institutes for BioMedical Research, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Powajbo+V%22">Powajbo V</searchLink>; Disease Area Oncology, Novartis Institutes for BioMedical Research, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Andraos-Rey+R%22">Andraos-Rey R</searchLink>; Disease Area Oncology, Novartis Institutes for BioMedical Research, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Qian+Z%22">Qian Z</searchLink>; Disease Area Oncology, Novartis Institutes for BioMedical Research, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Kininis+M%22">Kininis M</searchLink>; Disease Area Oncology, Novartis Institutes for BioMedical Research, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Zumstein-Mecker+S%22">Zumstein-Mecker S</searchLink>; Disease Area Oncology, Novartis Institutes for BioMedical Research, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Ito+M%22">Ito M</searchLink>; Disease Area Oncology, Novartis Institutes for BioMedical Research, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Hynes+NE%22">Hynes NE</searchLink>; Friedrich Miescher Institute for Biomedical Research, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Tiedt+R%22">Tiedt R</searchLink>; Disease Area Oncology, Novartis Institutes for BioMedical Research, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Hofmann+F%22">Hofmann F</searchLink>; Disease Area Oncology, Novartis Institutes for BioMedical Research, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Eshkind+L%22">Eshkind L</searchLink>; Institute for Translational Immunology and Research Center for Immunotherapy, University Medical Center, Johannes Gutenberg University, Mainz, Germany.<br /><searchLink fieldCode="AU" term="%22Bockamp+E%22">Bockamp E</searchLink>; Institute for Translational Immunology and Research Center for Immunotherapy, University Medical Center, Johannes Gutenberg University, Mainz, Germany.<br /><searchLink fieldCode="AU" term="%22Kinzel+B%22">Kinzel B</searchLink>; Chemical Biology and Therapeutics, Novartis Institutes for BioMedical Research, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Mueller+M%22">Mueller M</searchLink>; Chemical Biology and Therapeutics, Novartis Institutes for BioMedical Research, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Murakami+M%22">Murakami M</searchLink>; Disease Area Oncology, Novartis Institutes for BioMedical Research, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Baffert+F%22">Baffert F</searchLink>; Disease Area Oncology, Novartis Institutes for BioMedical Research, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Radimerski+T%22">Radimerski T</searchLink>; Disease Area Oncology, Novartis Institutes for BioMedical Research, Basel, Switzerland.
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  Data: <searchLink fieldCode="JN" term="%22101285081%22">PloS one</searchLink> [PLoS One] 2019 Oct 10; Vol. 14 (10), pp. e0221635. <i>Date of Electronic Publication: </i>2019 Oct 10 (<i>Print Publication: </i>2019).
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