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Selection design phase II trial of high dosages of tamoxifen and creatine in amyotrophic lateral sclerosis.

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Title: Selection design phase II trial of high dosages of tamoxifen and creatine in amyotrophic lateral sclerosis.
Authors: Babu S; Department of Neurology, Sean M Healey & AMG Center for ALS at Massachusetts General Hospital, Neurological Clinical Research Institute, Boston, MA, USA., Macklin EA; Biostatistics Center, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA., Jackson KE; Office of the Prescription Drug Monitoring Program, Maryland Department of Health, Baltimore, MD, USA., Simpson E; McCance Center for Brain Health at Massachusetts General Hospital, Boston, MA, USA., Mahoney K; Department of Neurology, Sean M Healey & AMG Center for ALS at Massachusetts General Hospital, Neurological Clinical Research Institute, Boston, MA, USA., Yu H; Department of Neurology, Sean M Healey & AMG Center for ALS at Massachusetts General Hospital, Neurological Clinical Research Institute, Boston, MA, USA., Walker J; Department of Neurology, Sean M Healey & AMG Center for ALS at Massachusetts General Hospital, Neurological Clinical Research Institute, Boston, MA, USA., Simmons Z; Penn State Health Hershey Medical Center, Hershey, PA, USA., David WS; Department of Neurology, Sean M Healey & AMG Center for ALS at Massachusetts General Hospital, Neurological Clinical Research Institute, Boston, MA, USA., Barkhaus PE; Medical College of Wisconsin, Milwaukee, WI, USA., Simionescu L; SUNY Upstate Medical Center, Syracuse, NY, USA., Dimachkie MM; University of Kansas Medical Center, Kansas City, KS, USA., Pestronk A; Washington University School of Medicine, St. Louis, MO, USA., Salameh JS; American University of Beirut Medical Center, Beirut, Lebanon., Weiss MD; University of Washington Medical Center, Seattle, WA, USA., Brooks BR; Atrium Health Neurosciences Institute, Carolinas Medical Center, University of North Carolina School of Medicine, Charlotte, NC, USA, and., Schoenfeld D; Biostatistics Center, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA., Shefner J; Barrow Neurological Institute and University of Arizona College of Medicine, Phoenix, AZ, USA., Aggarwal S; Department of Neurology, Sean M Healey & AMG Center for ALS at Massachusetts General Hospital, Neurological Clinical Research Institute, Boston, MA, USA., Cudkowicz ME; Department of Neurology, Sean M Healey & AMG Center for ALS at Massachusetts General Hospital, Neurological Clinical Research Institute, Boston, MA, USA., Atassi N; Department of Neurology, Sean M Healey & AMG Center for ALS at Massachusetts General Hospital, Neurological Clinical Research Institute, Boston, MA, USA.
Source: Amyotrophic lateral sclerosis & frontotemporal degeneration [Amyotroph Lateral Scler Frontotemporal Degener] 2020 Feb; Vol. 21 (1-2), pp. 15-23. Date of Electronic Publication: 2019 Oct 14.
Publication Type: Clinical Trial, Phase II; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Taylor & Francis Country of Publication: England NLM ID: 101587185 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2167-9223 (Electronic) Linking ISSN: 21678421 NLM ISO Abbreviation: Amyotroph Lateral Scler Frontotemporal Degener Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Babu+S%22">Babu S</searchLink>; Department of Neurology, Sean M Healey & AMG Center for ALS at Massachusetts General Hospital, Neurological Clinical Research Institute, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Macklin+EA%22">Macklin EA</searchLink>; Biostatistics Center, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Jackson+KE%22">Jackson KE</searchLink>; Office of the Prescription Drug Monitoring Program, Maryland Department of Health, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Simpson+E%22">Simpson E</searchLink>; McCance Center for Brain Health at Massachusetts General Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Mahoney+K%22">Mahoney K</searchLink>; Department of Neurology, Sean M Healey & AMG Center for ALS at Massachusetts General Hospital, Neurological Clinical Research Institute, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Yu+H%22">Yu H</searchLink>; Department of Neurology, Sean M Healey & AMG Center for ALS at Massachusetts General Hospital, Neurological Clinical Research Institute, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Walker+J%22">Walker J</searchLink>; Department of Neurology, Sean M Healey & AMG Center for ALS at Massachusetts General Hospital, Neurological Clinical Research Institute, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Simmons+Z%22">Simmons Z</searchLink>; Penn State Health Hershey Medical Center, Hershey, PA, USA.<br /><searchLink fieldCode="AU" term="%22David+WS%22">David WS</searchLink>; Department of Neurology, Sean M Healey & AMG Center for ALS at Massachusetts General Hospital, Neurological Clinical Research Institute, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Barkhaus+PE%22">Barkhaus PE</searchLink>; Medical College of Wisconsin, Milwaukee, WI, USA.<br /><searchLink fieldCode="AU" term="%22Simionescu+L%22">Simionescu L</searchLink>; SUNY Upstate Medical Center, Syracuse, NY, USA.<br /><searchLink fieldCode="AU" term="%22Dimachkie+MM%22">Dimachkie MM</searchLink>; University of Kansas Medical Center, Kansas City, KS, USA.<br /><searchLink fieldCode="AU" term="%22Pestronk+A%22">Pestronk A</searchLink>; Washington University School of Medicine, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Salameh+JS%22">Salameh JS</searchLink>; American University of Beirut Medical Center, Beirut, Lebanon.<br /><searchLink fieldCode="AU" term="%22Weiss+MD%22">Weiss MD</searchLink>; University of Washington Medical Center, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Brooks+BR%22">Brooks BR</searchLink>; Atrium Health Neurosciences Institute, Carolinas Medical Center, University of North Carolina School of Medicine, Charlotte, NC, USA, and.<br /><searchLink fieldCode="AU" term="%22Schoenfeld+D%22">Schoenfeld D</searchLink>; Biostatistics Center, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Shefner+J%22">Shefner J</searchLink>; Barrow Neurological Institute and University of Arizona College of Medicine, Phoenix, AZ, USA.<br /><searchLink fieldCode="AU" term="%22Aggarwal+S%22">Aggarwal S</searchLink>; Department of Neurology, Sean M Healey & AMG Center for ALS at Massachusetts General Hospital, Neurological Clinical Research Institute, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Cudkowicz+ME%22">Cudkowicz ME</searchLink>; Department of Neurology, Sean M Healey & AMG Center for ALS at Massachusetts General Hospital, Neurological Clinical Research Institute, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Atassi+N%22">Atassi N</searchLink>; Department of Neurology, Sean M Healey & AMG Center for ALS at Massachusetts General Hospital, Neurological Clinical Research Institute, Boston, MA, USA.
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  Data: <searchLink fieldCode="JN" term="%22101587185%22">Amyotrophic lateral sclerosis & frontotemporal degeneration</searchLink> [Amyotroph Lateral Scler Frontotemporal Degener] 2020 Feb; Vol. 21 (1-2), pp. 15-23. <i>Date of Electronic Publication: </i>2019 Oct 14.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Taylor+%26+Francis%22">Taylor & Francis </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101587185 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2167-9223 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2221678421%22">21678421 </searchLink><i>NLM ISO Abbreviation: </i>Amyotroph Lateral Scler Frontotemporal Degener <i>Subsets: </i>MEDLINE
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        Value: 10.1080/21678421.2019.1672750
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              Text: 2020 Feb
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