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Repurposing the aldose reductase inhibitor and diabetic neuropathy drug epalrestat for the congenital disorder of glycosylation PMM2-CDG.

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Bibliographic Details
Title: Repurposing the aldose reductase inhibitor and diabetic neuropathy drug epalrestat for the congenital disorder of glycosylation PMM2-CDG.
Authors: Iyer S; Perlara PBC, 2625 Alcatraz Ave #435, Berkeley, CA 94705, USA., Sam FS; Perlara PBC, 2625 Alcatraz Ave #435, Berkeley, CA 94705, USA., DiPrimio N; Perlara PBC, 2625 Alcatraz Ave #435, Berkeley, CA 94705, USA., Preston G; Department of Clinical Genomics and Department of Laboratory Medicine, Mayo Clinic, Rochester, MN 55902, USA., Verheijen J; Department of Clinical Genomics and Department of Laboratory Medicine, Mayo Clinic, Rochester, MN 55902, USA., Murthy K; Perlara PBC, 2625 Alcatraz Ave #435, Berkeley, CA 94705, USA., Parton Z; Perlara PBC, 2625 Alcatraz Ave #435, Berkeley, CA 94705, USA., Tsang H; Perlara PBC, 2625 Alcatraz Ave #435, Berkeley, CA 94705, USA., Lao J; Perlara PBC, 2625 Alcatraz Ave #435, Berkeley, CA 94705, USA., Morava E; Department of Clinical Genomics and Department of Laboratory Medicine, Mayo Clinic, Rochester, MN 55902, USA., Perlstein EO; Perlara PBC, 2625 Alcatraz Ave #435, Berkeley, CA 94705, USA ethan@perlara.com.
Source: Disease models & mechanisms [Dis Model Mech] 2019 Nov 11; Vol. 12 (11). Date of Electronic Publication: 2019 Nov 11.
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: Company of Biologists Ltd Country of Publication: England NLM ID: 101483332 Publication Model: Electronic Cited Medium: Internet ISSN: 1754-8411 (Electronic) Linking ISSN: 17548403 NLM ISO Abbreviation: Dis Model Mech Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1754-8411
DOI:10.1242/dmm.040584