View in EDS

The KRASG12C Inhibitor MRTX849 Provides Insight toward Therapeutic Susceptibility of KRAS-Mutant Cancers in Mouse Models and Patients.

Saved in:
Bibliographic Details
Title: The KRASG12C Inhibitor MRTX849 Provides Insight toward Therapeutic Susceptibility of KRAS-Mutant Cancers in Mouse Models and Patients.
Authors: Hallin J; Mirati Therapeutics, Inc., San Diego, California., Engstrom LD; Mirati Therapeutics, Inc., San Diego, California., Hargis L; Mirati Therapeutics, Inc., San Diego, California., Calinisan A; Mirati Therapeutics, Inc., San Diego, California., Aranda R; Mirati Therapeutics, Inc., San Diego, California., Briere DM; Mirati Therapeutics, Inc., San Diego, California., Sudhakar N; Mirati Therapeutics, Inc., San Diego, California., Bowcut V; Mirati Therapeutics, Inc., San Diego, California., Baer BR; Array BioPharma Inc., Boulder, Colorado., Ballard JA; Array BioPharma Inc., Boulder, Colorado., Burkard MR; Array BioPharma Inc., Boulder, Colorado., Fell JB; Array BioPharma Inc., Boulder, Colorado., Fischer JP; Array BioPharma Inc., Boulder, Colorado., Vigers GP; Array BioPharma Inc., Boulder, Colorado., Xue Y; Memorial Sloan Kettering Cancer Center, New York, New York., Gatto S; Monoceros Biosystems LLC, San Diego, California., Fernandez-Banet J; Monoceros Biosystems LLC, San Diego, California., Pavlicek A; Monoceros Biosystems LLC, San Diego, California., Velastagui K; Mirati Therapeutics, Inc., San Diego, California., Chao RC; Mirati Therapeutics, Inc., San Diego, California., Barton J; Mirati Therapeutics, Inc., San Diego, California., Pierobon M; George Mason University, Manassas, Virginia., Baldelli E; George Mason University, Manassas, Virginia., Patricoin EF 3rd; George Mason University, Manassas, Virginia., Cassidy DP; Dana-Farber Cancer Institute, Boston, Massachusetts., Marx MA; Mirati Therapeutics, Inc., San Diego, California., Rybkin II; Henry Ford Medical Center, Detroit, Michigan., Johnson ML; Sarah Cannon Research Institute Tennessee Oncology, Nashville, Tennessee., Ou SI; University of California, Irvine, Chao Family Comprehensive Cancer Center, Orange, California., Lito P; Memorial Sloan Kettering Cancer Center, New York, New York., Papadopoulos KP; START Center for Cancer Care, San Antonio, Texas., Jänne PA; Dana-Farber Cancer Institute, Boston, Massachusetts., Olson P; Mirati Therapeutics, Inc., San Diego, California., Christensen JG; Mirati Therapeutics, Inc., San Diego, California. christensenj@mirati.com.
Source: Cancer discovery [Cancer Discov] 2020 Jan; Vol. 10 (1), pp. 54-71. Date of Electronic Publication: 2019 Oct 28.
Publication Type: Case Reports; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 101561693 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2159-8290 (Electronic) Linking ISSN: 21598274 NLM ISO Abbreviation: Cancer Discov Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Text:
  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 31658955
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: The KRAS<superscript>G12C</superscript> Inhibitor MRTX849 Provides Insight toward Therapeutic Susceptibility of KRAS-Mutant Cancers in Mouse Models and Patients.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Hallin+J%22">Hallin J</searchLink>; Mirati Therapeutics, Inc., San Diego, California.<br /><searchLink fieldCode="AU" term="%22Engstrom+LD%22">Engstrom LD</searchLink>; Mirati Therapeutics, Inc., San Diego, California.<br /><searchLink fieldCode="AU" term="%22Hargis+L%22">Hargis L</searchLink>; Mirati Therapeutics, Inc., San Diego, California.<br /><searchLink fieldCode="AU" term="%22Calinisan+A%22">Calinisan A</searchLink>; Mirati Therapeutics, Inc., San Diego, California.<br /><searchLink fieldCode="AU" term="%22Aranda+R%22">Aranda R</searchLink>; Mirati Therapeutics, Inc., San Diego, California.<br /><searchLink fieldCode="AU" term="%22Briere+DM%22">Briere DM</searchLink>; Mirati Therapeutics, Inc., San Diego, California.<br /><searchLink fieldCode="AU" term="%22Sudhakar+N%22">Sudhakar N</searchLink>; Mirati Therapeutics, Inc., San Diego, California.<br /><searchLink fieldCode="AU" term="%22Bowcut+V%22">Bowcut V</searchLink>; Mirati Therapeutics, Inc., San Diego, California.<br /><searchLink fieldCode="AU" term="%22Baer+BR%22">Baer BR</searchLink>; Array BioPharma Inc., Boulder, Colorado.<br /><searchLink fieldCode="AU" term="%22Ballard+JA%22">Ballard JA</searchLink>; Array BioPharma Inc., Boulder, Colorado.<br /><searchLink fieldCode="AU" term="%22Burkard+MR%22">Burkard MR</searchLink>; Array BioPharma Inc., Boulder, Colorado.<br /><searchLink fieldCode="AU" term="%22Fell+JB%22">Fell JB</searchLink>; Array BioPharma Inc., Boulder, Colorado.<br /><searchLink fieldCode="AU" term="%22Fischer+JP%22">Fischer JP</searchLink>; Array BioPharma Inc., Boulder, Colorado.<br /><searchLink fieldCode="AU" term="%22Vigers+GP%22">Vigers GP</searchLink>; Array BioPharma Inc., Boulder, Colorado.<br /><searchLink fieldCode="AU" term="%22Xue+Y%22">Xue Y</searchLink>; Memorial Sloan Kettering Cancer Center, New York, New York.<br /><searchLink fieldCode="AU" term="%22Gatto+S%22">Gatto S</searchLink>; Monoceros Biosystems LLC, San Diego, California.<br /><searchLink fieldCode="AU" term="%22Fernandez-Banet+J%22">Fernandez-Banet J</searchLink>; Monoceros Biosystems LLC, San Diego, California.<br /><searchLink fieldCode="AU" term="%22Pavlicek+A%22">Pavlicek A</searchLink>; Monoceros Biosystems LLC, San Diego, California.<br /><searchLink fieldCode="AU" term="%22Velastagui+K%22">Velastagui K</searchLink>; Mirati Therapeutics, Inc., San Diego, California.<br /><searchLink fieldCode="AU" term="%22Chao+RC%22">Chao RC</searchLink>; Mirati Therapeutics, Inc., San Diego, California.<br /><searchLink fieldCode="AU" term="%22Barton+J%22">Barton J</searchLink>; Mirati Therapeutics, Inc., San Diego, California.<br /><searchLink fieldCode="AU" term="%22Pierobon+M%22">Pierobon M</searchLink>; George Mason University, Manassas, Virginia.<br /><searchLink fieldCode="AU" term="%22Baldelli+E%22">Baldelli E</searchLink>; George Mason University, Manassas, Virginia.<br /><searchLink fieldCode="AU" term="%22Patricoin+EF+3rd%22">Patricoin EF 3rd</searchLink>; George Mason University, Manassas, Virginia.<br /><searchLink fieldCode="AU" term="%22Cassidy+DP%22">Cassidy DP</searchLink>; Dana-Farber Cancer Institute, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Marx+MA%22">Marx MA</searchLink>; Mirati Therapeutics, Inc., San Diego, California.<br /><searchLink fieldCode="AU" term="%22Rybkin+II%22">Rybkin II</searchLink>; Henry Ford Medical Center, Detroit, Michigan.<br /><searchLink fieldCode="AU" term="%22Johnson+ML%22">Johnson ML</searchLink>; Sarah Cannon Research Institute Tennessee Oncology, Nashville, Tennessee.<br /><searchLink fieldCode="AU" term="%22Ou+SI%22">Ou SI</searchLink>; University of California, Irvine, Chao Family Comprehensive Cancer Center, Orange, California.<br /><searchLink fieldCode="AU" term="%22Lito+P%22">Lito P</searchLink>; Memorial Sloan Kettering Cancer Center, New York, New York.<br /><searchLink fieldCode="AU" term="%22Papadopoulos+KP%22">Papadopoulos KP</searchLink>; START Center for Cancer Care, San Antonio, Texas.<br /><searchLink fieldCode="AU" term="%22Jänne+PA%22">Jänne PA</searchLink>; Dana-Farber Cancer Institute, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Olson+P%22">Olson P</searchLink>; Mirati Therapeutics, Inc., San Diego, California.<br /><searchLink fieldCode="AU" term="%22Christensen+JG%22">Christensen JG</searchLink>; Mirati Therapeutics, Inc., San Diego, California. christensenj@mirati.com.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22101561693%22">Cancer discovery</searchLink> [Cancer Discov] 2020 Jan; Vol. 10 (1), pp. 54-71. <i>Date of Electronic Publication: </i>2019 Oct 28.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Case Reports; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Association+for+Cancer+Research%22">American Association for Cancer Research </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101561693 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2159-8290 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2221598274%22">21598274 </searchLink><i>NLM ISO Abbreviation: </i>Cancer Discov <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=31658955
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1158/2159-8290.CD-19-1167
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: 54
    Titles:
      – TitleFull: The KRASG12C Inhibitor MRTX849 Provides Insight toward Therapeutic Susceptibility of KRAS-Mutant Cancers in Mouse Models and Patients.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Hallin J
      – PersonEntity:
          Name:
            NameFull: Engstrom LD
      – PersonEntity:
          Name:
            NameFull: Hargis L
      – PersonEntity:
          Name:
            NameFull: Calinisan A
      – PersonEntity:
          Name:
            NameFull: Aranda R
      – PersonEntity:
          Name:
            NameFull: Briere DM
      – PersonEntity:
          Name:
            NameFull: Sudhakar N
      – PersonEntity:
          Name:
            NameFull: Bowcut V
      – PersonEntity:
          Name:
            NameFull: Baer BR
      – PersonEntity:
          Name:
            NameFull: Ballard JA
      – PersonEntity:
          Name:
            NameFull: Burkard MR
      – PersonEntity:
          Name:
            NameFull: Fell JB
      – PersonEntity:
          Name:
            NameFull: Fischer JP
      – PersonEntity:
          Name:
            NameFull: Vigers GP
      – PersonEntity:
          Name:
            NameFull: Xue Y
      – PersonEntity:
          Name:
            NameFull: Gatto S
      – PersonEntity:
          Name:
            NameFull: Fernandez-Banet J
      – PersonEntity:
          Name:
            NameFull: Pavlicek A
      – PersonEntity:
          Name:
            NameFull: Velastagui K
      – PersonEntity:
          Name:
            NameFull: Chao RC
      – PersonEntity:
          Name:
            NameFull: Barton J
      – PersonEntity:
          Name:
            NameFull: Pierobon M
      – PersonEntity:
          Name:
            NameFull: Baldelli E
      – PersonEntity:
          Name:
            NameFull: Patricoin EF 3rd
      – PersonEntity:
          Name:
            NameFull: Cassidy DP
      – PersonEntity:
          Name:
            NameFull: Marx MA
      – PersonEntity:
          Name:
            NameFull: Rybkin II
      – PersonEntity:
          Name:
            NameFull: Johnson ML
      – PersonEntity:
          Name:
            NameFull: Ou SI
      – PersonEntity:
          Name:
            NameFull: Lito P
      – PersonEntity:
          Name:
            NameFull: Papadopoulos KP
      – PersonEntity:
          Name:
            NameFull: Jänne PA
      – PersonEntity:
          Name:
            NameFull: Olson P
      – PersonEntity:
          Name:
            NameFull: Christensen JG
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 01
              Text: 2020 Jan
              Type: published
              Y: 2020
          Identifiers:
            – Type: issn-electronic
              Value: 2159-8290
          Numbering:
            – Type: volume
              Value: 10
            – Type: issue
              Value: 1
          Titles:
            – TitleFull: Cancer discovery
              Type: main
ResultId 1