An anionic, endosome-escaping polymer to potentiate intracellular delivery of cationic peptides, biomacromolecules, and nanoparticles.

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Title: An anionic, endosome-escaping polymer to potentiate intracellular delivery of cationic peptides, biomacromolecules, and nanoparticles.
Authors: Evans BC; Department of Biomedical Engineering, Vanderbilt University, 2301 Vanderbilt Place, PMB351826, Nashville, TN, 37235, USA. brian.evans@vanderbilt.edu., Fletcher RB; Department of Biomedical Engineering, Vanderbilt University, 2301 Vanderbilt Place, PMB351826, Nashville, TN, 37235, USA., Kilchrist KV; Department of Biomedical Engineering, Vanderbilt University, 2301 Vanderbilt Place, PMB351826, Nashville, TN, 37235, USA., Dailing EA; Department of Biomedical Engineering, Vanderbilt University, 2301 Vanderbilt Place, PMB351826, Nashville, TN, 37235, USA., Mukalel AJ; Department of Bioengineering, University of Pennsylvania, 2301 240 Skirkanich Hall, 210S. 33rd Street, Philadelphia, PA, 19104-6321, USA., Colazo JM; Department of Biomedical Engineering, Vanderbilt University, 2301 Vanderbilt Place, PMB351826, Nashville, TN, 37235, USA.; Vanderbilt University School of Medicine, Vanderbilt University, 1161 21st Avenue South # D3300, Nashville, TN, 37232, USA.; Medical Scientist Training Program, Vanderbilt University School of Medicine, Nashville, TN, 37232, USA., Oliver M; Program in Cell and Molecular Biology, Duke University School of Medicine, Durham, NC, 27710, USA., Cheung-Flynn J; Division of Vascular Surgery, Department of Surgery, Vanderbilt University Medical Center, D-5237 Medical Center North, 1161 22nd Avenue South, Nashville, TN, 37232, USA., Brophy CM; Division of Vascular Surgery, Department of Surgery, Vanderbilt University Medical Center, D-5237 Medical Center North, 1161 22nd Avenue South, Nashville, TN, 37232, USA.; Veterans Affairs Medical Center, VA Tennessee Valley Healthcare System, 1310 24th Avenue South, Nashville, TN, 37212, USA., Tierney JW; Department of Biomedical Engineering, Vanderbilt University, 2301 Vanderbilt Place, PMB351826, Nashville, TN, 37235, USA., Isenberg JS; Heart, Lung, Blood and Vascular Medicine Institute, Department of Medicine, University of Pittsburgh, 4200 Fifth Avenue, Pittsburgh, PA, 15260, USA., Hankenson KD; Department of Orthopaedic Surgery, University of Michigan Medical School, 109 Zina Pitcher Place, Ann Arbor, MI, 48109, USA., Ghimire K; University of Pittsburgh School of Medicine, 3550 Terrace Street, Pittsburgh, PA, 15261, USA., Lander C; Moerae Matrix Inc., 55 Madison Avenue, Suite 400, Morristown, NJ, 07960, USA., Gersbach CA; Center for Genomic and Computational Biology, Duke University, Durham, NC, 27710, USA.; Department of Biomedical Engineering, Duke University, Durham, NC, 27710, USA.; Department of Orthopaedic Surgery, Duke University, Durham, NC, 27710, USA., Duvall CL; Department of Biomedical Engineering, Vanderbilt University, 2301 Vanderbilt Place, PMB351826, Nashville, TN, 37235, USA. craig.duvall@vanderbilt.edu.
Source: Nature communications [Nat Commun] 2019 Nov 01; Vol. 10 (1), pp. 5012. Date of Electronic Publication: 2019 Nov 01.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2041-1723
DOI:10.1038/s41467-019-12906-y