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Cephalosporin nitric oxide-donor prodrug DEA-C3D disperses biofilms formed by clinical cystic fibrosis isolates of Pseudomonas aeruginosa.

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Title: Cephalosporin nitric oxide-donor prodrug DEA-C3D disperses biofilms formed by clinical cystic fibrosis isolates of Pseudomonas aeruginosa.
Authors: Soren O; National Biofilms Innovation Centre, University of Southampton, Southampton SO17 1BJ, UK.; Biological Sciences and Institute for Life Sciences, University of Southampton, Southampton SO17 1BJ, UK., Rineh A; Molecular Horizons and School of Chemistry & Molecular Bioscience, University of Wollongong, NSW, 2522, Australia.; Illawarra Health & Medical Research Institute, Wollongong, NSW, 2522, Australia., Silva DG; National Biofilms Innovation Centre, University of Southampton, Southampton SO17 1BJ, UK.; Faculty of Medicine and Institute for Life Sciences, University of Southampton and University Hospital Southampton NHS Foundation Trust, Southampton SO16 6YD, UK., Cai Y; National Biofilms Innovation Centre, University of Southampton, Southampton SO17 1BJ, UK.; Biological Sciences and Institute for Life Sciences, University of Southampton, Southampton SO17 1BJ, UK., Howlin RP; Biological Sciences and Institute for Life Sciences, University of Southampton, Southampton SO17 1BJ, UK.; NIHR Southampton Clinical Research Facility and NIHR Southampton Biomedical Research Centre, University Hospital Southampton NHS Foundation, Southampton SO16 6YD, UK., Allan RN; National Biofilms Innovation Centre, University of Southampton, Southampton SO17 1BJ, UK.; Biological Sciences and Institute for Life Sciences, University of Southampton, Southampton SO17 1BJ, UK.; NIHR Southampton Clinical Research Facility and NIHR Southampton Biomedical Research Centre, University Hospital Southampton NHS Foundation, Southampton SO16 6YD, UK., Feelisch M; Faculty of Medicine and Institute for Life Sciences, University of Southampton and University Hospital Southampton NHS Foundation Trust, Southampton SO16 6YD, UK., Davies JC; Cystic Fibrosis Trust Strategic Research Centre and National Heart and Lung Institute, Imperial College London, London SW3 6LY, UK., Connett GJ; National Biofilms Innovation Centre, University of Southampton, Southampton SO17 1BJ, UK.; Faculty of Medicine and Institute for Life Sciences, University of Southampton and University Hospital Southampton NHS Foundation Trust, Southampton SO16 6YD, UK.; NIHR Southampton Clinical Research Facility and NIHR Southampton Biomedical Research Centre, University Hospital Southampton NHS Foundation, Southampton SO16 6YD, UK., Faust SN; National Biofilms Innovation Centre, University of Southampton, Southampton SO17 1BJ, UK.; Faculty of Medicine and Institute for Life Sciences, University of Southampton and University Hospital Southampton NHS Foundation Trust, Southampton SO16 6YD, UK.; NIHR Southampton Clinical Research Facility and NIHR Southampton Biomedical Research Centre, University Hospital Southampton NHS Foundation, Southampton SO16 6YD, UK., Kelso MJ; Molecular Horizons and School of Chemistry & Molecular Bioscience, University of Wollongong, NSW, 2522, Australia.; Illawarra Health & Medical Research Institute, Wollongong, NSW, 2522, Australia., Webb JS; National Biofilms Innovation Centre, University of Southampton, Southampton SO17 1BJ, UK.; Biological Sciences and Institute for Life Sciences, University of Southampton, Southampton SO17 1BJ, UK.; NIHR Southampton Clinical Research Facility and NIHR Southampton Biomedical Research Centre, University Hospital Southampton NHS Foundation, Southampton SO16 6YD, UK.
Source: The Journal of antimicrobial chemotherapy [J Antimicrob Chemother] 2020 Jan 01; Vol. 75 (1), pp. 117-125.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 7513617 Publication Model: Print Cited Medium: Internet ISSN: 1460-2091 (Electronic) Linking ISSN: 03057453 NLM ISO Abbreviation: J Antimicrob Chemother Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Cephalosporin nitric oxide-donor prodrug DEA-C3D disperses biofilms formed by clinical cystic fibrosis isolates of Pseudomonas aeruginosa.
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  Data: <searchLink fieldCode="AU" term="%22Soren+O%22">Soren O</searchLink>; National Biofilms Innovation Centre, University of Southampton, Southampton SO17 1BJ, UK.; Biological Sciences and Institute for Life Sciences, University of Southampton, Southampton SO17 1BJ, UK.<br /><searchLink fieldCode="AU" term="%22Rineh+A%22">Rineh A</searchLink>; Molecular Horizons and School of Chemistry & Molecular Bioscience, University of Wollongong, NSW, 2522, Australia.; Illawarra Health & Medical Research Institute, Wollongong, NSW, 2522, Australia.<br /><searchLink fieldCode="AU" term="%22Silva+DG%22">Silva DG</searchLink>; National Biofilms Innovation Centre, University of Southampton, Southampton SO17 1BJ, UK.; Faculty of Medicine and Institute for Life Sciences, University of Southampton and University Hospital Southampton NHS Foundation Trust, Southampton SO16 6YD, UK.<br /><searchLink fieldCode="AU" term="%22Cai+Y%22">Cai Y</searchLink>; National Biofilms Innovation Centre, University of Southampton, Southampton SO17 1BJ, UK.; Biological Sciences and Institute for Life Sciences, University of Southampton, Southampton SO17 1BJ, UK.<br /><searchLink fieldCode="AU" term="%22Howlin+RP%22">Howlin RP</searchLink>; Biological Sciences and Institute for Life Sciences, University of Southampton, Southampton SO17 1BJ, UK.; NIHR Southampton Clinical Research Facility and NIHR Southampton Biomedical Research Centre, University Hospital Southampton NHS Foundation, Southampton SO16 6YD, UK.<br /><searchLink fieldCode="AU" term="%22Allan+RN%22">Allan RN</searchLink>; National Biofilms Innovation Centre, University of Southampton, Southampton SO17 1BJ, UK.; Biological Sciences and Institute for Life Sciences, University of Southampton, Southampton SO17 1BJ, UK.; NIHR Southampton Clinical Research Facility and NIHR Southampton Biomedical Research Centre, University Hospital Southampton NHS Foundation, Southampton SO16 6YD, UK.<br /><searchLink fieldCode="AU" term="%22Feelisch+M%22">Feelisch M</searchLink>; Faculty of Medicine and Institute for Life Sciences, University of Southampton and University Hospital Southampton NHS Foundation Trust, Southampton SO16 6YD, UK.<br /><searchLink fieldCode="AU" term="%22Davies+JC%22">Davies JC</searchLink>; Cystic Fibrosis Trust Strategic Research Centre and National Heart and Lung Institute, Imperial College London, London SW3 6LY, UK.<br /><searchLink fieldCode="AU" term="%22Connett+GJ%22">Connett GJ</searchLink>; National Biofilms Innovation Centre, University of Southampton, Southampton SO17 1BJ, UK.; Faculty of Medicine and Institute for Life Sciences, University of Southampton and University Hospital Southampton NHS Foundation Trust, Southampton SO16 6YD, UK.; NIHR Southampton Clinical Research Facility and NIHR Southampton Biomedical Research Centre, University Hospital Southampton NHS Foundation, Southampton SO16 6YD, UK.<br /><searchLink fieldCode="AU" term="%22Faust+SN%22">Faust SN</searchLink>; National Biofilms Innovation Centre, University of Southampton, Southampton SO17 1BJ, UK.; Faculty of Medicine and Institute for Life Sciences, University of Southampton and University Hospital Southampton NHS Foundation Trust, Southampton SO16 6YD, UK.; NIHR Southampton Clinical Research Facility and NIHR Southampton Biomedical Research Centre, University Hospital Southampton NHS Foundation, Southampton SO16 6YD, UK.<br /><searchLink fieldCode="AU" term="%22Kelso+MJ%22">Kelso MJ</searchLink>; Molecular Horizons and School of Chemistry & Molecular Bioscience, University of Wollongong, NSW, 2522, Australia.; Illawarra Health & Medical Research Institute, Wollongong, NSW, 2522, Australia.<br /><searchLink fieldCode="AU" term="%22Webb+JS%22">Webb JS</searchLink>; National Biofilms Innovation Centre, University of Southampton, Southampton SO17 1BJ, UK.; Biological Sciences and Institute for Life Sciences, University of Southampton, Southampton SO17 1BJ, UK.; NIHR Southampton Clinical Research Facility and NIHR Southampton Biomedical Research Centre, University Hospital Southampton NHS Foundation, Southampton SO16 6YD, UK.
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      – TitleFull: Cephalosporin nitric oxide-donor prodrug DEA-C3D disperses biofilms formed by clinical cystic fibrosis isolates of Pseudomonas aeruginosa.
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