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Constitutive activation of MEK1 in osteoprogenitors increases strength of bone despite impairing mineralization.

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Bibliographic Details
Title: Constitutive activation of MEK1 in osteoprogenitors increases strength of bone despite impairing mineralization.
Authors: Fowlkes JL; University of Kentucky Barnstable Brown Diabetes Center, Lexington, KY, 40536, United States; Department of Pediatrics, University of Kentucky College of Medicine, Lexington, KY, 40536, United States. Electronic address: fowlkesjohnl@uky.edu., Bunn RC; University of Kentucky Barnstable Brown Diabetes Center, Lexington, KY, 40536, United States; Department of Pediatrics, University of Kentucky College of Medicine, Lexington, KY, 40536, United States., Ray PD; University of Kentucky Barnstable Brown Diabetes Center, Lexington, KY, 40536, United States; Department of Pediatrics, University of Kentucky College of Medicine, Lexington, KY, 40536, United States., Kalaitzoglou E; University of Kentucky Barnstable Brown Diabetes Center, Lexington, KY, 40536, United States; Department of Pediatrics, University of Kentucky College of Medicine, Lexington, KY, 40536, United States., Uppuganti S; Department of Orthopaedic Surgery and Rehabilitation, Vanderbilt University Medical Center, Nashville, TN, 37232, United States; Center for Bone Biology, Vanderbilt University Medical Center, Nashville, TN, 37232, United States., Unal M; Department of Orthopaedic Surgery and Rehabilitation, Vanderbilt University Medical Center, Nashville, TN, 37232, United States; Center for Bone Biology, Vanderbilt University Medical Center, Nashville, TN, 37232, United States., Nyman JS; Department of Orthopaedic Surgery and Rehabilitation, Vanderbilt University Medical Center, Nashville, TN, 37232, United States; Department of Biomedical Engineering, Vanderbilt University, Nashville, TN, 37232, United States; Center for Bone Biology, Vanderbilt University Medical Center, Nashville, TN, 37232, United States; Department of Veterans Affairs, Tennessee Valley Healthcare System, Nashville, TN, 37212, United States., Thrailkill KM; University of Kentucky Barnstable Brown Diabetes Center, Lexington, KY, 40536, United States; Department of Pediatrics, University of Kentucky College of Medicine, Lexington, KY, 40536, United States.
Source: Bone [Bone] 2020 Jan; Vol. 130, pp. 115106. Date of Electronic Publication: 2019 Nov 02.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Elsevier Science Country of Publication: United States NLM ID: 8504048 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2763 (Electronic) Linking ISSN: 18732763 NLM ISO Abbreviation: Bone Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1873-2763
DOI:10.1016/j.bone.2019.115106