The phosphodiesterase-4 inhibitor roflumilast impacts Schistosoma mansoni ovipositing in vitro but displays only modest antischistosomal activity in vivo. - Botros SS; El-Lakkany NM; Seif El-Din SH; William S; Sabra AN; Hammam OA; de Koning HP (Experimental parasitology, 2020)