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PRAS40 suppresses atherogenesis through inhibition of mTORC1-dependent pro-inflammatory signaling in endothelial cells.

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Title: PRAS40 suppresses atherogenesis through inhibition of mTORC1-dependent pro-inflammatory signaling in endothelial cells.
Authors: Zhang KS; Department of Cardiology, Angiology, and Pneumology, University Hospital Heidelberg, University of Heidelberg, Heidelberg, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Heidelberg/Mannheim, Heidelberg, Germany., Schecker J; Charité - University Medicine Berlin, Department of Cardiology and Angiology, Charité Campus Mitte, Berlin, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Berlin, Berlin, Germany., Krull A; Charité - University Medicine Berlin, Department of Cardiology and Angiology, Charité Campus Mitte, Berlin, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Berlin, Berlin, Germany., Riechert E; Department of Cardiology, Angiology, and Pneumology, University Hospital Heidelberg, University of Heidelberg, Heidelberg, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Heidelberg/Mannheim, Heidelberg, Germany., Jürgensen L; Department of Cardiology, Angiology, and Pneumology, University Hospital Heidelberg, University of Heidelberg, Heidelberg, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Heidelberg/Mannheim, Heidelberg, Germany., Kamuf-Schenk V; Department of Cardiology, Angiology, and Pneumology, University Hospital Heidelberg, University of Heidelberg, Heidelberg, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Heidelberg/Mannheim, Heidelberg, Germany., Burghaus J; Department of Cardiology, Angiology, and Pneumology, University Hospital Heidelberg, University of Heidelberg, Heidelberg, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Heidelberg/Mannheim, Heidelberg, Germany., Kiper L; Department of Cardiology, Angiology, and Pneumology, University Hospital Heidelberg, University of Heidelberg, Heidelberg, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Heidelberg/Mannheim, Heidelberg, Germany., Cao Ho T; Department of Cardiology, Angiology, and Pneumology, University Hospital Heidelberg, University of Heidelberg, Heidelberg, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Heidelberg/Mannheim, Heidelberg, Germany., Wöltje K; Charité - University Medicine Berlin, Department of Cardiology and Angiology, Charité Campus Mitte, Berlin, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Berlin, Berlin, Germany., Stangl V; Charité - University Medicine Berlin, Department of Cardiology and Angiology, Charité Campus Mitte, Berlin, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Berlin, Berlin, Germany., Katus HA; Department of Cardiology, Angiology, and Pneumology, University Hospital Heidelberg, University of Heidelberg, Heidelberg, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Heidelberg/Mannheim, Heidelberg, Germany., Stangl K; Charité - University Medicine Berlin, Department of Cardiology and Angiology, Charité Campus Mitte, Berlin, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Berlin, Berlin, Germany., Völkers M; Department of Cardiology, Angiology, and Pneumology, University Hospital Heidelberg, University of Heidelberg, Heidelberg, Germany. mirko.voelkers@med.uni-heidelberg.de.; DZHK (German Centre for Cardiovascular Research), partner site Heidelberg/Mannheim, Heidelberg, Germany. mirko.voelkers@med.uni-heidelberg.de., Althoff TF; Charité - University Medicine Berlin, Department of Cardiology and Angiology, Charité Campus Mitte, Berlin, Germany. till.althoff@charite.de.; DZHK (German Centre for Cardiovascular Research), partner site Berlin, Berlin, Germany. till.althoff@charite.de.
Source: Scientific reports [Sci Rep] 2019 Nov 14; Vol. 9 (1), pp. 16787. Date of Electronic Publication: 2019 Nov 14.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
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  Data: PRAS40 suppresses atherogenesis through inhibition of mTORC1-dependent pro-inflammatory signaling in endothelial cells.
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  Data: <searchLink fieldCode="AU" term="%22Zhang+KS%22">Zhang KS</searchLink>; Department of Cardiology, Angiology, and Pneumology, University Hospital Heidelberg, University of Heidelberg, Heidelberg, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Heidelberg/Mannheim, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Schecker+J%22">Schecker J</searchLink>; Charité - University Medicine Berlin, Department of Cardiology and Angiology, Charité Campus Mitte, Berlin, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Berlin, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Krull+A%22">Krull A</searchLink>; Charité - University Medicine Berlin, Department of Cardiology and Angiology, Charité Campus Mitte, Berlin, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Berlin, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Riechert+E%22">Riechert E</searchLink>; Department of Cardiology, Angiology, and Pneumology, University Hospital Heidelberg, University of Heidelberg, Heidelberg, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Heidelberg/Mannheim, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Jürgensen+L%22">Jürgensen L</searchLink>; Department of Cardiology, Angiology, and Pneumology, University Hospital Heidelberg, University of Heidelberg, Heidelberg, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Heidelberg/Mannheim, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Kamuf-Schenk+V%22">Kamuf-Schenk V</searchLink>; Department of Cardiology, Angiology, and Pneumology, University Hospital Heidelberg, University of Heidelberg, Heidelberg, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Heidelberg/Mannheim, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Burghaus+J%22">Burghaus J</searchLink>; Department of Cardiology, Angiology, and Pneumology, University Hospital Heidelberg, University of Heidelberg, Heidelberg, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Heidelberg/Mannheim, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Kiper+L%22">Kiper L</searchLink>; Department of Cardiology, Angiology, and Pneumology, University Hospital Heidelberg, University of Heidelberg, Heidelberg, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Heidelberg/Mannheim, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Cao+Ho+T%22">Cao Ho T</searchLink>; Department of Cardiology, Angiology, and Pneumology, University Hospital Heidelberg, University of Heidelberg, Heidelberg, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Heidelberg/Mannheim, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Wöltje+K%22">Wöltje K</searchLink>; Charité - University Medicine Berlin, Department of Cardiology and Angiology, Charité Campus Mitte, Berlin, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Berlin, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Stangl+V%22">Stangl V</searchLink>; Charité - University Medicine Berlin, Department of Cardiology and Angiology, Charité Campus Mitte, Berlin, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Berlin, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Katus+HA%22">Katus HA</searchLink>; Department of Cardiology, Angiology, and Pneumology, University Hospital Heidelberg, University of Heidelberg, Heidelberg, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Heidelberg/Mannheim, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Stangl+K%22">Stangl K</searchLink>; Charité - University Medicine Berlin, Department of Cardiology and Angiology, Charité Campus Mitte, Berlin, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Berlin, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Völkers+M%22">Völkers M</searchLink>; Department of Cardiology, Angiology, and Pneumology, University Hospital Heidelberg, University of Heidelberg, Heidelberg, Germany. mirko.voelkers@med.uni-heidelberg.de.; DZHK (German Centre for Cardiovascular Research), partner site Heidelberg/Mannheim, Heidelberg, Germany. mirko.voelkers@med.uni-heidelberg.de.<br /><searchLink fieldCode="AU" term="%22Althoff+TF%22">Althoff TF</searchLink>; Charité - University Medicine Berlin, Department of Cardiology and Angiology, Charité Campus Mitte, Berlin, Germany. till.althoff@charite.de.; DZHK (German Centre for Cardiovascular Research), partner site Berlin, Berlin, Germany. till.althoff@charite.de.
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