Population pharmacokinetics, exposure-safety, and immunogenicity of atezolizumab in pediatric and young adult patients with cancer.
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| Title: | Population pharmacokinetics, exposure-safety, and immunogenicity of atezolizumab in pediatric and young adult patients with cancer. |
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| Authors: | Shemesh CS; Department of Clinical Pharmacology Oncology, Genentech Inc., South San Francisco, CA, 94080, USA. shemesh.colby@gene.com., Chanu P; Clinical Pharmacology, Modeling and Simulation, Genentech/Roche, Marseille, France., Jamsen K; Certara Strategic Consulting, Princeton, NJ, USA., Wada R; Certara Strategic Consulting, Princeton, NJ, USA., Rossato G; Clinical Science, F. Hoffmann-La Roche Ltd, Basel, Switzerland., Donaldson F; Safety Science, Roche Products Ltd, Welwyn Garden City, UK., Garg A; Department of Clinical Pharmacology Oncology, Genentech Inc., South San Francisco, CA, 94080, USA.; Present address: Quantitative Pharmacology and Disposition, Seattle Genetics, South San Francisco, CA, USA., Winter H; Department of Clinical Pharmacology Oncology, Genentech Inc., South San Francisco, CA, 94080, USA.; Present address: Quantitative Pharmacology and Disposition, Seattle Genetics, South San Francisco, CA, USA., Ruppel J; Bioanalytical Sciences, Genentech Inc., South San Francisco, CA, USA., Wang X; Department of Clinical Pharmacology Oncology, Genentech Inc., South San Francisco, CA, 94080, USA., Bruno R; Clinical Pharmacology, Modeling and Simulation, Genentech/Roche, Marseille, France., Jin J; Department of Clinical Pharmacology Oncology, Genentech Inc., South San Francisco, CA, 94080, USA., Girish S; Department of Clinical Pharmacology Oncology, Genentech Inc., South San Francisco, CA, 94080, USA. |
| Source: | Journal for immunotherapy of cancer [J Immunother Cancer] 2019 Nov 21; Vol. 7 (1), pp. 314. Date of Electronic Publication: 2019 Nov 21. |
| Publication Type: | Clinical Trial, Phase I; Clinical Trial, Phase II; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: BMJ Publishing Group Ltd Country of Publication: England NLM ID: 101620585 Publication Model: Electronic Cited Medium: Internet ISSN: 2051-1426 (Electronic) Linking ISSN: 20511426 NLM ISO Abbreviation: J Immunother Cancer Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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