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EED-Targeted PROTACs Degrade EED, EZH2, and SUZ12 in the PRC2 Complex.

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Title: EED-Targeted PROTACs Degrade EED, EZH2, and SUZ12 in the PRC2 Complex.
Authors: Hsu JH; Oncology R&D, AstraZeneca, Waltham, MA 02451, USA., Rasmusson T; Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Waltham, MA 02451, USA., Robinson J; Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Cambridge CB4 0FZ, UK., Pachl F; Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Waltham, MA 02451, USA., Read J; Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Cambridge CB4 0FZ, UK., Kawatkar S; Oncology R&D, AstraZeneca, Waltham, MA 02451, USA., O' Donovan DH; Oncology R&D, AstraZeneca, Cambridge CB4 0FZ, UK., Bagal S; Oncology R&D, AstraZeneca, Cambridge CB4 0FZ, UK., Code E; Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Waltham, MA 02451, USA., Rawlins P; Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Cambridge CB4 0FZ, UK., Argyrou A; Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Cambridge CB4 0FZ, UK., Tomlinson R; Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Waltham, MA 02451, USA., Gao N; Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Waltham, MA 02451, USA., Zhu X; Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Waltham, MA 02451, USA., Chiarparin E; Oncology R&D, AstraZeneca, Cambridge CB4 0FZ, UK., Jacques K; Oncology R&D, AstraZeneca, Waltham, MA 02451, USA., Shen M; Oncology R&D, AstraZeneca, Waltham, MA 02451, USA., Woods H; Oncology R&D, AstraZeneca, Waltham, MA 02451, USA., Bednarski E; Oncology R&D, AstraZeneca, Waltham, MA 02451, USA., Wilson DM; Oncology R&D, AstraZeneca, Cambridge CB4 0FZ, UK., Drew L; Oncology R&D, AstraZeneca, Waltham, MA 02451, USA., Castaldi MP; Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Waltham, MA 02451, USA., Fawell S; Oncology R&D, AstraZeneca, Waltham, MA 02451, USA., Bloecher A; Oncology R&D, AstraZeneca, Waltham, MA 02451, USA. Electronic address: andrew.bloecher@astrazeneca.com.
Source: Cell chemical biology [Cell Chem Biol] 2020 Jan 16; Vol. 27 (1), pp. 41-46.e17. Date of Electronic Publication: 2019 Nov 27.
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101676030 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2451-9448 (Electronic) Linking ISSN: 24519448 NLM ISO Abbreviation: Cell Chem Biol Subsets: MEDLINE
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  Data: EED-Targeted PROTACs Degrade EED, EZH2, and SUZ12 in the PRC2 Complex.
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  Data: <searchLink fieldCode="JN" term="%22101676030%22">Cell chemical biology</searchLink> [Cell Chem Biol] 2020 Jan 16; Vol. 27 (1), pp. 41-46.e17. <i>Date of Electronic Publication: </i>2019 Nov 27.
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