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Multi-trait genome-wide association study identifies new loci associated with optic disc parameters.

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Title: Multi-trait genome-wide association study identifies new loci associated with optic disc parameters.
Authors: Bonnemaijer PWM; 1Department of Ophthalmology, Erasmus MC, Rotterdam, The Netherlands.; 2Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands.; 3The Rotterdam Eye Hospital, Rotterdam, The Netherlands., Leeuwen EMV; 1Department of Ophthalmology, Erasmus MC, Rotterdam, The Netherlands.; 2Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands., Iglesias AI; 1Department of Ophthalmology, Erasmus MC, Rotterdam, The Netherlands.; 2Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands.; 4Department of Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands., Gharahkhani P; Statistical Genetics, QIMR Berghofer Medical Research Institute, Royal Brisbane Hospital, Brisbane, Australia., Vitart V; 6Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Khawaja AP; 7NIHR Biomedical Research Centre, Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, London, UK., Simcoe M; 8Twin Research and Genetic Epidemiology, King's College London, London, UK., Höhn R; Department of Ophthalmology, Inselspital, University Hospital Bern, University of Bern, Bern, Germany.; 10Department of Ophthalmology, University Medical Center Mainz, Mainz, Germany., Cree AJ; 11Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK., Igo RP; 12Department of Ophthalmology, Harvard Medical School, Boston, MA USA., Gerhold-Ay A; 13Institute of Medical Biostatistics, Epidemiology and Informatics, University Medical Center Mainz, Mainz, Germany., Nickels S; 10Department of Ophthalmology, University Medical Center Mainz, Mainz, Germany., Wilson JF; 6Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK.; 14Centre for Global Health Research, The Usher Institute for Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK., Hayward C; 6Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Boutin TS; 6Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Polašek O; 15Faculty of Medicine, University of Split, Split, Croatia., Aung T; 16Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore.; 17Ophthalmology & Visual Sciences Academic Clinical Program, Duke-NUS Medical School, Singapore, Singapore.; 18Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Khor CC; 19Division of Human Genetics, Genome Institute of Singapore, Singapore, Singapore., Amin N; 2Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands., Lotery AJ; 11Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK., Wiggs JL; 12Department of Ophthalmology, Harvard Medical School, Boston, MA USA., Cheng CY; 16Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore.; 17Ophthalmology & Visual Sciences Academic Clinical Program, Duke-NUS Medical School, Singapore, Singapore.; 18Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Hysi PG; 8Twin Research and Genetic Epidemiology, King's College London, London, UK., Hammond CJ; 8Twin Research and Genetic Epidemiology, King's College London, London, UK., Thiadens AAHJ; 1Department of Ophthalmology, Erasmus MC, Rotterdam, The Netherlands.; 2Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands., MacGregor S; Statistical Genetics, QIMR Berghofer Medical Research Institute, Royal Brisbane Hospital, Brisbane, Australia., Klaver CCW; 1Department of Ophthalmology, Erasmus MC, Rotterdam, The Netherlands.; 2Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands.; Department of Ophthalmology, Radboud Medical Center, Nijmegen, The Netherlands.; Institute for Molecular and Clinical Ophthalmology, Basel, Switzerland., Duijn CMV; 2Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands.; 22Nuffield Department of Public Health, University of Oxford, Oxford, UK.
Corporate Authors: International Glaucoma Genetics Consortium, NEIGHBORHOOD consortium, UK Biobank Eye and Vision Consortium
Source: Communications biology [Commun Biol] 2019 Nov 27; Vol. 2, pp. 435. Date of Electronic Publication: 2019 Nov 27 (Print Publication: 2019).
Publication Type: Journal Article; Meta-Analysis; Research Support, American Recovery and Reinvestment Act; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Publishing Group UK Country of Publication: England NLM ID: 101719179 Publication Model: eCollection Cited Medium: Internet ISSN: 2399-3642 (Electronic) Linking ISSN: 23993642 NLM ISO Abbreviation: Commun Biol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Multi-trait genome-wide association study identifies new loci associated with optic disc parameters.
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  Data: <searchLink fieldCode="AU" term="%22Bonnemaijer+PWM%22">Bonnemaijer PWM</searchLink>; 1Department of Ophthalmology, Erasmus MC, Rotterdam, The Netherlands.; 2Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands.; 3The Rotterdam Eye Hospital, Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Leeuwen+EMV%22">Leeuwen EMV</searchLink>; 1Department of Ophthalmology, Erasmus MC, Rotterdam, The Netherlands.; 2Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Iglesias+AI%22">Iglesias AI</searchLink>; 1Department of Ophthalmology, Erasmus MC, Rotterdam, The Netherlands.; 2Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands.; 4Department of Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Gharahkhani+P%22">Gharahkhani P</searchLink>; Statistical Genetics, QIMR Berghofer Medical Research Institute, Royal Brisbane Hospital, Brisbane, Australia.<br /><searchLink fieldCode="AU" term="%22Vitart+V%22">Vitart V</searchLink>; 6Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Khawaja+AP%22">Khawaja AP</searchLink>; 7NIHR Biomedical Research Centre, Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, London, UK.<br /><searchLink fieldCode="AU" term="%22Simcoe+M%22">Simcoe M</searchLink>; 8Twin Research and Genetic Epidemiology, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Höhn+R%22">Höhn R</searchLink>; Department of Ophthalmology, Inselspital, University Hospital Bern, University of Bern, Bern, Germany.; 10Department of Ophthalmology, University Medical Center Mainz, Mainz, Germany.<br /><searchLink fieldCode="AU" term="%22Cree+AJ%22">Cree AJ</searchLink>; 11Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK.<br /><searchLink fieldCode="AU" term="%22Igo+RP%22">Igo RP</searchLink>; 12Department of Ophthalmology, Harvard Medical School, Boston, MA USA.<br /><searchLink fieldCode="AU" term="%22Gerhold-Ay+A%22">Gerhold-Ay A</searchLink>; 13Institute of Medical Biostatistics, Epidemiology and Informatics, University Medical Center Mainz, Mainz, Germany.<br /><searchLink fieldCode="AU" term="%22Nickels+S%22">Nickels S</searchLink>; 10Department of Ophthalmology, University Medical Center Mainz, Mainz, Germany.<br /><searchLink fieldCode="AU" term="%22Wilson+JF%22">Wilson JF</searchLink>; 6Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK.; 14Centre for Global Health Research, The Usher Institute for Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Hayward+C%22">Hayward C</searchLink>; 6Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Boutin+TS%22">Boutin TS</searchLink>; 6Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Polašek+O%22">Polašek O</searchLink>; 15Faculty of Medicine, University of Split, Split, Croatia.<br /><searchLink fieldCode="AU" term="%22Aung+T%22">Aung T</searchLink>; 16Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore.; 17Ophthalmology & Visual Sciences Academic Clinical Program, Duke-NUS Medical School, Singapore, Singapore.; 18Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Khor+CC%22">Khor CC</searchLink>; 19Division of Human Genetics, Genome Institute of Singapore, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Amin+N%22">Amin N</searchLink>; 2Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Lotery+AJ%22">Lotery AJ</searchLink>; 11Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK.<br /><searchLink fieldCode="AU" term="%22Wiggs+JL%22">Wiggs JL</searchLink>; 12Department of Ophthalmology, Harvard Medical School, Boston, MA USA.<br /><searchLink fieldCode="AU" term="%22Cheng+CY%22">Cheng CY</searchLink>; 16Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore.; 17Ophthalmology & Visual Sciences Academic Clinical Program, Duke-NUS Medical School, Singapore, Singapore.; 18Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Hysi+PG%22">Hysi PG</searchLink>; 8Twin Research and Genetic Epidemiology, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Hammond+CJ%22">Hammond CJ</searchLink>; 8Twin Research and Genetic Epidemiology, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Thiadens+AAHJ%22">Thiadens AAHJ</searchLink>; 1Department of Ophthalmology, Erasmus MC, Rotterdam, The Netherlands.; 2Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22MacGregor+S%22">MacGregor S</searchLink>; Statistical Genetics, QIMR Berghofer Medical Research Institute, Royal Brisbane Hospital, Brisbane, Australia.<br /><searchLink fieldCode="AU" term="%22Klaver+CCW%22">Klaver CCW</searchLink>; 1Department of Ophthalmology, Erasmus MC, Rotterdam, The Netherlands.; 2Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands.; Department of Ophthalmology, Radboud Medical Center, Nijmegen, The Netherlands.; Institute for Molecular and Clinical Ophthalmology, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Duijn+CMV%22">Duijn CMV</searchLink>; 2Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands.; 22Nuffield Department of Public Health, University of Oxford, Oxford, UK.
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  Data: <searchLink fieldCode="JN" term="%22101719179%22">Communications biology</searchLink> [Commun Biol] 2019 Nov 27; Vol. 2, pp. 435. <i>Date of Electronic Publication: </i>2019 Nov 27 (<i>Print Publication: </i>2019).
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