Multi-trait genome-wide association study identifies new loci associated with optic disc parameters.
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| Title: | Multi-trait genome-wide association study identifies new loci associated with optic disc parameters. |
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| Authors: | Bonnemaijer PWM; 1Department of Ophthalmology, Erasmus MC, Rotterdam, The Netherlands.; 2Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands.; 3The Rotterdam Eye Hospital, Rotterdam, The Netherlands., Leeuwen EMV; 1Department of Ophthalmology, Erasmus MC, Rotterdam, The Netherlands.; 2Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands., Iglesias AI; 1Department of Ophthalmology, Erasmus MC, Rotterdam, The Netherlands.; 2Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands.; 4Department of Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands., Gharahkhani P; Statistical Genetics, QIMR Berghofer Medical Research Institute, Royal Brisbane Hospital, Brisbane, Australia., Vitart V; 6Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Khawaja AP; 7NIHR Biomedical Research Centre, Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, London, UK., Simcoe M; 8Twin Research and Genetic Epidemiology, King's College London, London, UK., Höhn R; Department of Ophthalmology, Inselspital, University Hospital Bern, University of Bern, Bern, Germany.; 10Department of Ophthalmology, University Medical Center Mainz, Mainz, Germany., Cree AJ; 11Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK., Igo RP; 12Department of Ophthalmology, Harvard Medical School, Boston, MA USA., Gerhold-Ay A; 13Institute of Medical Biostatistics, Epidemiology and Informatics, University Medical Center Mainz, Mainz, Germany., Nickels S; 10Department of Ophthalmology, University Medical Center Mainz, Mainz, Germany., Wilson JF; 6Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK.; 14Centre for Global Health Research, The Usher Institute for Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK., Hayward C; 6Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Boutin TS; 6Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Polašek O; 15Faculty of Medicine, University of Split, Split, Croatia., Aung T; 16Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore.; 17Ophthalmology & Visual Sciences Academic Clinical Program, Duke-NUS Medical School, Singapore, Singapore.; 18Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Khor CC; 19Division of Human Genetics, Genome Institute of Singapore, Singapore, Singapore., Amin N; 2Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands., Lotery AJ; 11Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK., Wiggs JL; 12Department of Ophthalmology, Harvard Medical School, Boston, MA USA., Cheng CY; 16Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore.; 17Ophthalmology & Visual Sciences Academic Clinical Program, Duke-NUS Medical School, Singapore, Singapore.; 18Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Hysi PG; 8Twin Research and Genetic Epidemiology, King's College London, London, UK., Hammond CJ; 8Twin Research and Genetic Epidemiology, King's College London, London, UK., Thiadens AAHJ; 1Department of Ophthalmology, Erasmus MC, Rotterdam, The Netherlands.; 2Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands., MacGregor S; Statistical Genetics, QIMR Berghofer Medical Research Institute, Royal Brisbane Hospital, Brisbane, Australia., Klaver CCW; 1Department of Ophthalmology, Erasmus MC, Rotterdam, The Netherlands.; 2Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands.; Department of Ophthalmology, Radboud Medical Center, Nijmegen, The Netherlands.; Institute for Molecular and Clinical Ophthalmology, Basel, Switzerland., Duijn CMV; 2Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands.; 22Nuffield Department of Public Health, University of Oxford, Oxford, UK. |
| Corporate Authors: | International Glaucoma Genetics Consortium, NEIGHBORHOOD consortium, UK Biobank Eye and Vision Consortium |
| Source: | Communications biology [Commun Biol] 2019 Nov 27; Vol. 2, pp. 435. Date of Electronic Publication: 2019 Nov 27 (Print Publication: 2019). |
| Publication Type: | Journal Article; Meta-Analysis; Research Support, American Recovery and Reinvestment Act; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Nature Publishing Group UK Country of Publication: England NLM ID: 101719179 Publication Model: eCollection Cited Medium: Internet ISSN: 2399-3642 (Electronic) Linking ISSN: 23993642 NLM ISO Abbreviation: Commun Biol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2399-3642 |
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| DOI: | 10.1038/s42003-019-0634-9 |
