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Multicentre, randomised trial to investigate early nasal high-flow therapy in paediatric acute hypoxaemic respiratory failure: a protocol for a randomised controlled trial-a Paediatric Acute respiratory Intervention Study (PARIS 2).

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Title: Multicentre, randomised trial to investigate early nasal high-flow therapy in paediatric acute hypoxaemic respiratory failure: a protocol for a randomised controlled trial-a Paediatric Acute respiratory Intervention Study (PARIS 2).
Authors: Franklin D; Paediatric Critical Care Research Group, Child Health Research Centre, The University of Queensland, Brisbane, Queensland, Australia d.franklin2@uq.edu.au.; School of Medicine, The University Of Queensland, St Lucia, Queensland, Australia.; Mater Medical Research Institute, South Brisbane, Queensland, Australia.; Paediatric Research in Emergency Departments International Collaborative (PREDICT), Parkville, Victoria, Australia., Shellshear D; Paediatric Research in Emergency Departments International Collaborative (PREDICT), Parkville, Victoria, Australia.; Emergency Department, Queensland Children's Hospital, South Brisbane, Queensland, Australia.; Queensland Children's Hospital, South Brisbane, Queensland, Australia., Babl FE; Paediatric Research in Emergency Departments International Collaborative (PREDICT), Parkville, Victoria, Australia.; Emergency Department, Royal Childrens Hospital, Parkville, Victoria, Australia.; Murdoch Children's Research Institute, Melbourne, Victoria, Australia.; Department of Paediatrics, Faculty of Medicine, Dentistry and Health Services, University of Melbourne, Melbourne, Victoria, Australia., Schlapbach LJ; Paediatric Critical Care Research Group, Child Health Research Centre, The University of Queensland, Brisbane, Queensland, Australia.; School of Medicine, The University Of Queensland, St Lucia, Queensland, Australia.; Queensland Children's Hospital, South Brisbane, Queensland, Australia., Oakley E; Paediatric Research in Emergency Departments International Collaborative (PREDICT), Parkville, Victoria, Australia.; Emergency Department, Royal Childrens Hospital, Parkville, Victoria, Australia.; Murdoch Children's Research Institute, Melbourne, Victoria, Australia.; Department of Paediatrics, Faculty of Medicine, Dentistry and Health Services, University of Melbourne, Melbourne, Victoria, Australia., Borland ML; Paediatric Research in Emergency Departments International Collaborative (PREDICT), Parkville, Victoria, Australia.; Emergency, Princess Margaret Hospital for Children, Subiaco, Western Australia, Australia.; University of Western Australia, School of Medicine, Divisions of Emergency Medicine and Paediatrics, Crawley, Western Australia, Australia., Hoeppner T; Paediatric Research in Emergency Departments International Collaborative (PREDICT), Parkville, Victoria, Australia.; Emergency, Princess Margaret Hospital for Children, Subiaco, Western Australia, Australia., George S; Paediatric Critical Care Research Group, Child Health Research Centre, The University of Queensland, Brisbane, Queensland, Australia.; School of Medicine, The University Of Queensland, St Lucia, Queensland, Australia.; Paediatric Research in Emergency Departments International Collaborative (PREDICT), Parkville, Victoria, Australia.; Emergency Department, Gold Coast University Hospital, Southport, Queensland, Australia., Craig S; Paediatric Research in Emergency Departments International Collaborative (PREDICT), Parkville, Victoria, Australia.; Emergency Department, Monash Medical Centre Clayton, Clayton, Victoria, Australia.; Department of Medicine, School of Clinical Science, Monash University, Clayton, Victoria, Australia., Neutze J; Paediatric Research in Emergency Departments International Collaborative (PREDICT), Parkville, Victoria, Australia.; KidzFirst Middlemore Emergency Department, Middlemore Hospital, Auckland, New Zealand.; University of Auckland, Auckland, New Zealand., Williams A; Paediatric Research in Emergency Departments International Collaborative (PREDICT), Parkville, Victoria, Australia.; Emergency Department, Royal Childrens Hospital, Parkville, Victoria, Australia.; Murdoch Children's Research Institute, Melbourne, Victoria, Australia., Acworth J; School of Medicine, The University Of Queensland, St Lucia, Queensland, Australia.; Paediatric Research in Emergency Departments International Collaborative (PREDICT), Parkville, Victoria, Australia.; Emergency Department, Queensland Children's Hospital, South Brisbane, Queensland, Australia., McCay H; Paediatrics, Waikato Hospital, Hamilton, New Zealand., Wallace A; Paediatrics, Waikato Hospital, Hamilton, New Zealand., Mattes J; Paediatrics, John Hunter Children's Hospital, Hunter Region Mail Centre, New South Wales, Australia.; University of Newcastle, Priority Research Centre GrowUpWell, Callaghan, New South Wales, Australia., Gangathimn V; Paediatric Research in Emergency Departments International Collaborative (PREDICT), Parkville, Victoria, Australia.; Emergency Department, Townsville General Hospital, Townsville, Queensland, Australia., Wildman M; Paediatric Research in Emergency Departments International Collaborative (PREDICT), Parkville, Victoria, Australia.; Emergency Department, Townsville General Hospital, Townsville, Queensland, Australia., Fraser JF; Adult Intensive Care Services, The Prince Charles Hospital, Brisbane, Queensland, Australia.; Critical Care Research Group, The Prince Charles Hospital and University of Queensland, Brisbane, Queensland, Australia., Moloney S; Paediatric Department, Gold Coast University Hospital, Southport, Queensland, Australia., Gavranich J; Paediatrics, Ipswich Hospital, Ipswich, Queensland, Australia., Waugh J; Paediatrics, Caboolture Hospital, Caboolture, Queensland, Australia., Hobbins S; Paediatrics, Prince Charles Hospital, Chermside, Queensland, Australia., Fahy R; Paediatrics, Prince Charles Hospital, Chermside, Queensland, Australia., Grew S; Paediatrics, Redcliffe Hospital, Redcliffe, Queensland, Australia., Gannon B; The University of Queensland, Centre for Business and Economics of Health, St Lucia Qld, Queensland, Australia., Gibbons K; Paediatric Critical Care Research Group, Child Health Research Centre, The University of Queensland, Brisbane, Queensland, Australia.; Mater Medical Research Institute, South Brisbane, Queensland, Australia., Dalziel S; Paediatric Research in Emergency Departments International Collaborative (PREDICT), Parkville, Victoria, Australia.; University of Auckland, Auckland, New Zealand.; Starship Children's Health, Emergency Department, Newmarket, New Zealand.; Department of Surgery and Paediatrics, Child and Youth Health, University of Auckland, Auckland, New Zealand., Schibler A; Paediatric Critical Care Research Group, Child Health Research Centre, The University of Queensland, Brisbane, Queensland, Australia.; School of Medicine, The University Of Queensland, St Lucia, Queensland, Australia.; Mater Medical Research Institute, South Brisbane, Queensland, Australia.; Paediatric Research in Emergency Departments International Collaborative (PREDICT), Parkville, Victoria, Australia.; Queensland Children's Hospital, South Brisbane, Queensland, Australia.
Corporate Authors: PARIS and PREDICT
Source: BMJ open [BMJ Open] 2019 Dec 18; Vol. 9 (12), pp. e030516. Date of Electronic Publication: 2019 Dec 18.
Publication Type: Clinical Trial Protocol; Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: BMJ Publishing Group Ltd Country of Publication: England NLM ID: 101552874 Publication Model: Electronic Cited Medium: Internet ISSN: 2044-6055 (Electronic) Linking ISSN: 20446055 NLM ISO Abbreviation: BMJ Open Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Multicentre, randomised trial to investigate early nasal high-flow therapy in paediatric acute hypoxaemic respiratory failure: a protocol for a randomised controlled trial-a Paediatric Acute respiratory Intervention Study (PARIS 2).
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  Data: <searchLink fieldCode="AU" term="%22Franklin+D%22">Franklin D</searchLink>; Paediatric Critical Care Research Group, Child Health Research Centre, The University of Queensland, Brisbane, Queensland, Australia d.franklin2@uq.edu.au.; School of Medicine, The University Of Queensland, St Lucia, Queensland, Australia.; Mater Medical Research Institute, South Brisbane, Queensland, Australia.; Paediatric Research in Emergency Departments International Collaborative (PREDICT), Parkville, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Shellshear+D%22">Shellshear D</searchLink>; Paediatric Research in Emergency Departments International Collaborative (PREDICT), Parkville, Victoria, Australia.; Emergency Department, Queensland Children's Hospital, South Brisbane, Queensland, Australia.; Queensland Children's Hospital, South Brisbane, Queensland, Australia.<br /><searchLink fieldCode="AU" term="%22Babl+FE%22">Babl FE</searchLink>; Paediatric Research in Emergency Departments International Collaborative (PREDICT), Parkville, Victoria, Australia.; Emergency Department, Royal Childrens Hospital, Parkville, Victoria, Australia.; Murdoch Children's Research Institute, Melbourne, Victoria, Australia.; Department of Paediatrics, Faculty of Medicine, Dentistry and Health Services, University of Melbourne, Melbourne, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Schlapbach+LJ%22">Schlapbach LJ</searchLink>; Paediatric Critical Care Research Group, Child Health Research Centre, The University of Queensland, Brisbane, Queensland, Australia.; School of Medicine, The University Of Queensland, St Lucia, Queensland, Australia.; Queensland Children's Hospital, South Brisbane, Queensland, Australia.<br /><searchLink fieldCode="AU" term="%22Oakley+E%22">Oakley E</searchLink>; Paediatric Research in Emergency Departments International Collaborative (PREDICT), Parkville, Victoria, Australia.; Emergency Department, Royal Childrens Hospital, Parkville, Victoria, Australia.; Murdoch Children's Research Institute, Melbourne, Victoria, Australia.; Department of Paediatrics, Faculty of Medicine, Dentistry and Health Services, University of Melbourne, Melbourne, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Borland+ML%22">Borland ML</searchLink>; Paediatric Research in Emergency Departments International Collaborative (PREDICT), Parkville, Victoria, Australia.; Emergency, Princess Margaret Hospital for Children, Subiaco, Western Australia, Australia.; University of Western Australia, School of Medicine, Divisions of Emergency Medicine and Paediatrics, Crawley, Western Australia, Australia.<br /><searchLink fieldCode="AU" term="%22Hoeppner+T%22">Hoeppner T</searchLink>; Paediatric Research in Emergency Departments International Collaborative (PREDICT), Parkville, Victoria, Australia.; Emergency, Princess Margaret Hospital for Children, Subiaco, Western Australia, Australia.<br /><searchLink fieldCode="AU" term="%22George+S%22">George S</searchLink>; Paediatric Critical Care Research Group, Child Health Research Centre, The University of Queensland, Brisbane, Queensland, Australia.; School of Medicine, The University Of Queensland, St Lucia, Queensland, Australia.; Paediatric Research in Emergency Departments International Collaborative (PREDICT), Parkville, Victoria, Australia.; Emergency Department, Gold Coast University Hospital, Southport, Queensland, Australia.<br /><searchLink fieldCode="AU" term="%22Craig+S%22">Craig S</searchLink>; Paediatric Research in Emergency Departments International Collaborative (PREDICT), Parkville, Victoria, Australia.; Emergency Department, Monash Medical Centre Clayton, Clayton, Victoria, Australia.; Department of Medicine, School of Clinical Science, Monash University, Clayton, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Neutze+J%22">Neutze J</searchLink>; Paediatric Research in Emergency Departments International Collaborative (PREDICT), Parkville, Victoria, Australia.; KidzFirst Middlemore Emergency Department, Middlemore Hospital, Auckland, New Zealand.; University of Auckland, Auckland, New Zealand.<br /><searchLink fieldCode="AU" term="%22Williams+A%22">Williams A</searchLink>; Paediatric Research in Emergency Departments International Collaborative (PREDICT), Parkville, Victoria, Australia.; Emergency Department, Royal Childrens Hospital, Parkville, Victoria, Australia.; Murdoch Children's Research Institute, Melbourne, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Acworth+J%22">Acworth J</searchLink>; School of Medicine, The University Of Queensland, St Lucia, Queensland, Australia.; Paediatric Research in Emergency Departments International Collaborative (PREDICT), Parkville, Victoria, Australia.; Emergency Department, Queensland Children's Hospital, South Brisbane, Queensland, Australia.<br /><searchLink fieldCode="AU" term="%22McCay+H%22">McCay H</searchLink>; Paediatrics, Waikato Hospital, Hamilton, New Zealand.<br /><searchLink fieldCode="AU" term="%22Wallace+A%22">Wallace A</searchLink>; Paediatrics, Waikato Hospital, Hamilton, New Zealand.<br /><searchLink fieldCode="AU" term="%22Mattes+J%22">Mattes J</searchLink>; Paediatrics, John Hunter Children's Hospital, Hunter Region Mail Centre, New South Wales, Australia.; University of Newcastle, Priority Research Centre GrowUpWell, Callaghan, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Gangathimn+V%22">Gangathimn V</searchLink>; Paediatric Research in Emergency Departments International Collaborative (PREDICT), Parkville, Victoria, Australia.; Emergency Department, Townsville General Hospital, Townsville, Queensland, Australia.<br /><searchLink fieldCode="AU" term="%22Wildman+M%22">Wildman M</searchLink>; Paediatric Research in Emergency Departments International Collaborative (PREDICT), Parkville, Victoria, Australia.; Emergency Department, Townsville General Hospital, Townsville, Queensland, Australia.<br /><searchLink fieldCode="AU" term="%22Fraser+JF%22">Fraser JF</searchLink>; Adult Intensive Care Services, The Prince Charles Hospital, Brisbane, Queensland, Australia.; Critical Care Research Group, The Prince Charles Hospital and University of Queensland, Brisbane, Queensland, Australia.<br /><searchLink fieldCode="AU" term="%22Moloney+S%22">Moloney S</searchLink>; Paediatric Department, Gold Coast University Hospital, Southport, Queensland, Australia.<br /><searchLink fieldCode="AU" term="%22Gavranich+J%22">Gavranich J</searchLink>; Paediatrics, Ipswich Hospital, Ipswich, Queensland, Australia.<br /><searchLink fieldCode="AU" term="%22Waugh+J%22">Waugh J</searchLink>; Paediatrics, Caboolture Hospital, Caboolture, Queensland, Australia.<br /><searchLink fieldCode="AU" term="%22Hobbins+S%22">Hobbins S</searchLink>; Paediatrics, Prince Charles Hospital, Chermside, Queensland, Australia.<br /><searchLink fieldCode="AU" term="%22Fahy+R%22">Fahy R</searchLink>; Paediatrics, Prince Charles Hospital, Chermside, Queensland, Australia.<br /><searchLink fieldCode="AU" term="%22Grew+S%22">Grew S</searchLink>; Paediatrics, Redcliffe Hospital, Redcliffe, Queensland, Australia.<br /><searchLink fieldCode="AU" term="%22Gannon+B%22">Gannon B</searchLink>; The University of Queensland, Centre for Business and Economics of Health, St Lucia Qld, Queensland, Australia.<br /><searchLink fieldCode="AU" term="%22Gibbons+K%22">Gibbons K</searchLink>; Paediatric Critical Care Research Group, Child Health Research Centre, The University of Queensland, Brisbane, Queensland, Australia.; Mater Medical Research Institute, South Brisbane, Queensland, Australia.<br /><searchLink fieldCode="AU" term="%22Dalziel+S%22">Dalziel S</searchLink>; Paediatric Research in Emergency Departments International Collaborative (PREDICT), Parkville, Victoria, Australia.; University of Auckland, Auckland, New Zealand.; Starship Children's Health, Emergency Department, Newmarket, New Zealand.; Department of Surgery and Paediatrics, Child and Youth Health, University of Auckland, Auckland, New Zealand.<br /><searchLink fieldCode="AU" term="%22Schibler+A%22">Schibler A</searchLink>; Paediatric Critical Care Research Group, Child Health Research Centre, The University of Queensland, Brisbane, Queensland, Australia.; School of Medicine, The University Of Queensland, St Lucia, Queensland, Australia.; Mater Medical Research Institute, South Brisbane, Queensland, Australia.; Paediatric Research in Emergency Departments International Collaborative (PREDICT), Parkville, Victoria, Australia.; Queensland Children's Hospital, South Brisbane, Queensland, Australia.
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