Structural analysis of mycobacterial homoserine transacetylases central to methionine biosynthesis reveals druggable active site.
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| Title: | Structural analysis of mycobacterial homoserine transacetylases central to methionine biosynthesis reveals druggable active site. |
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| Authors: | Chaton CT; Department of Molecular & Cellular Biochemistry and the Center for Structural Biology, University of Kentucky, Lexington, KY, 40536, USA., Rodriguez ES; Department of Molecular & Cellular Biochemistry and the Center for Structural Biology, University of Kentucky, Lexington, KY, 40536, USA.; Department of Chemistry & Biochemistry, Ohio State University, Columbus, OH, 43210, USA., Reed RW; Department of Molecular & Cellular Biochemistry and the Center for Structural Biology, University of Kentucky, Lexington, KY, 40536, USA.; Division of Regulatory Services, College of Agriculture, Food and Environment, University of Kentucky, Lexington, KY, 40546, USA., Li J; Department of Molecular & Cellular Biochemistry and the Center for Structural Biology, University of Kentucky, Lexington, KY, 40536, USA.; Gannan Medical University, Ganzhou, Jiangxi, 341000, China., Kenner CW; Department of Molecular & Cellular Biochemistry and the Center for Structural Biology, University of Kentucky, Lexington, KY, 40536, USA.; Georgetown College, Georgetown, KY, 40324, USA., Korotkov KV; Department of Molecular & Cellular Biochemistry and the Center for Structural Biology, University of Kentucky, Lexington, KY, 40536, USA. kkorotkov@uky.edu. |
| Source: | Scientific reports [Sci Rep] 2019 Dec 30; Vol. 9 (1), pp. 20267. Date of Electronic Publication: 2019 Dec 30. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S. |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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