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Scalable Prediction of Acute Myeloid Leukemia Using High-Dimensional Machine Learning and Blood Transcriptomics.

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Title: Scalable Prediction of Acute Myeloid Leukemia Using High-Dimensional Machine Learning and Blood Transcriptomics.
Authors: Warnat-Herresthal S; LIMES-Institute, Department for Genomics and Immunoregulation, University of Bonn, Carl-Troll-Str. 31, 53115 Bonn, Germany., Perrakis K; Statistics and Machine Learning, German Center for Neurodegenerative Diseases, Venusberg-Campus 1, Building 99, 53127 Bonn, Germany., Taschler B; Statistics and Machine Learning, German Center for Neurodegenerative Diseases, Venusberg-Campus 1, Building 99, 53127 Bonn, Germany., Becker M; PRECISE Platform for Single Cell Genomics and Epigenomics, German Center for Neurodegenerative Diseases and the University of Bonn, Venusberg-Campus 1, Building 99, 53127 Bonn, Germany., Baßler K; LIMES-Institute, Department for Genomics and Immunoregulation, University of Bonn, Carl-Troll-Str. 31, 53115 Bonn, Germany., Beyer M; Molecular Immunology in Neurodegeneration, German Center for Neurodegenerative Diseases, Venusberg-Campus 1, Building 99, 53127 Bonn, Germany; PRECISE Platform for Single Cell Genomics and Epigenomics, German Center for Neurodegenerative Diseases and the University of Bonn, Venusberg-Campus 1, Building 99, 53127 Bonn, Germany., Günther P; LIMES-Institute, Department for Genomics and Immunoregulation, University of Bonn, Carl-Troll-Str. 31, 53115 Bonn, Germany., Schulte-Schrepping J; LIMES-Institute, Department for Genomics and Immunoregulation, University of Bonn, Carl-Troll-Str. 31, 53115 Bonn, Germany., Seep L; LIMES-Institute, Department for Genomics and Immunoregulation, University of Bonn, Carl-Troll-Str. 31, 53115 Bonn, Germany., Klee K; LIMES-Institute, Department for Genomics and Immunoregulation, University of Bonn, Carl-Troll-Str. 31, 53115 Bonn, Germany., Ulas T; LIMES-Institute, Department for Genomics and Immunoregulation, University of Bonn, Carl-Troll-Str. 31, 53115 Bonn, Germany., Haferlach T; MLL, Münchner Leukämielabor GmbH, Max-Lebsche-Platz 31, 81377 München, Germany., Mukherjee S; Statistics and Machine Learning, German Center for Neurodegenerative Diseases, Venusberg-Campus 1, Building 99, 53127 Bonn, Germany. Electronic address: sach.mukherjee@dzne.de., Schultze JL; LIMES-Institute, Department for Genomics and Immunoregulation, University of Bonn, Carl-Troll-Str. 31, 53115 Bonn, Germany; PRECISE Platform for Single Cell Genomics and Epigenomics, German Center for Neurodegenerative Diseases and the University of Bonn, Venusberg-Campus 1, Building 99, 53127 Bonn, Germany. Electronic address: j.schultze@uni-bonn.de.
Source: IScience [iScience] 2020 Jan 24; Vol. 23 (1), pp. 100780. Date of Electronic Publication: 2019 Dec 18.
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101724038 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2589-0042 (Electronic) Linking ISSN: 25890042 NLM ISO Abbreviation: iScience Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Warnat-Herresthal+S%22">Warnat-Herresthal S</searchLink>; LIMES-Institute, Department for Genomics and Immunoregulation, University of Bonn, Carl-Troll-Str. 31, 53115 Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Perrakis+K%22">Perrakis K</searchLink>; Statistics and Machine Learning, German Center for Neurodegenerative Diseases, Venusberg-Campus 1, Building 99, 53127 Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Taschler+B%22">Taschler B</searchLink>; Statistics and Machine Learning, German Center for Neurodegenerative Diseases, Venusberg-Campus 1, Building 99, 53127 Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Becker+M%22">Becker M</searchLink>; PRECISE Platform for Single Cell Genomics and Epigenomics, German Center for Neurodegenerative Diseases and the University of Bonn, Venusberg-Campus 1, Building 99, 53127 Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Baßler+K%22">Baßler K</searchLink>; LIMES-Institute, Department for Genomics and Immunoregulation, University of Bonn, Carl-Troll-Str. 31, 53115 Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Beyer+M%22">Beyer M</searchLink>; Molecular Immunology in Neurodegeneration, German Center for Neurodegenerative Diseases, Venusberg-Campus 1, Building 99, 53127 Bonn, Germany; PRECISE Platform for Single Cell Genomics and Epigenomics, German Center for Neurodegenerative Diseases and the University of Bonn, Venusberg-Campus 1, Building 99, 53127 Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Günther+P%22">Günther P</searchLink>; LIMES-Institute, Department for Genomics and Immunoregulation, University of Bonn, Carl-Troll-Str. 31, 53115 Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Schulte-Schrepping+J%22">Schulte-Schrepping J</searchLink>; LIMES-Institute, Department for Genomics and Immunoregulation, University of Bonn, Carl-Troll-Str. 31, 53115 Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Seep+L%22">Seep L</searchLink>; LIMES-Institute, Department for Genomics and Immunoregulation, University of Bonn, Carl-Troll-Str. 31, 53115 Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Klee+K%22">Klee K</searchLink>; LIMES-Institute, Department for Genomics and Immunoregulation, University of Bonn, Carl-Troll-Str. 31, 53115 Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Ulas+T%22">Ulas T</searchLink>; LIMES-Institute, Department for Genomics and Immunoregulation, University of Bonn, Carl-Troll-Str. 31, 53115 Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Haferlach+T%22">Haferlach T</searchLink>; MLL, Münchner Leukämielabor GmbH, Max-Lebsche-Platz 31, 81377 München, Germany.<br /><searchLink fieldCode="AU" term="%22Mukherjee+S%22">Mukherjee S</searchLink>; Statistics and Machine Learning, German Center for Neurodegenerative Diseases, Venusberg-Campus 1, Building 99, 53127 Bonn, Germany. Electronic address: sach.mukherjee@dzne.de.<br /><searchLink fieldCode="AU" term="%22Schultze+JL%22">Schultze JL</searchLink>; LIMES-Institute, Department for Genomics and Immunoregulation, University of Bonn, Carl-Troll-Str. 31, 53115 Bonn, Germany; PRECISE Platform for Single Cell Genomics and Epigenomics, German Center for Neurodegenerative Diseases and the University of Bonn, Venusberg-Campus 1, Building 99, 53127 Bonn, Germany. Electronic address: j.schultze@uni-bonn.de.
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