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Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure.

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Title: Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure.
Authors: Shah S; Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, 4072, Australia.; Institute of Cardiovascular Science, University College London, London, UK.; British Heart Foundation Research Accelerator, University College London, London, UK., Henry A; Institute of Cardiovascular Science, University College London, London, UK.; British Heart Foundation Research Accelerator, University College London, London, UK.; Institute of Health Informatics, University College London, London, UK., Roselli C; Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands., Lin H; Section of Computational Biomedicine, Department of Medicine, Boston University School of Medicine, Boston, MA, USA.; National Heart, Lung, and Blood Institute's and Boston University's Framingham Heart Study, Framingham, MA, USA., Sveinbjörnsson G; deCODE genetics/Amgen Inc., Sturlugata 8, 101, Reykjavik, Iceland., Fatemifar G; British Heart Foundation Research Accelerator, University College London, London, UK.; Institute of Health Informatics, University College London, London, UK.; Health Data Research UK London, University College London, London, UK., Hedman ÅK; Cardiovascular Medicine unit, Department of Medicine Solna, Karolinska Institute, Stockholm, Sweden., Wilk JB; Pfizer Worldwide Research & Development, 1 Portland St, Cambridge, MA, USA., Morley MP; Penn Cardiovascular Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Chaffin MD; Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, MA, USA., Helgadottir A; deCODE genetics/Amgen Inc., Sturlugata 8, 101, Reykjavik, Iceland., Verweij N; Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands., Dehghan A; Department of Epidemiology and Biostatistics, Imperial College London, St Mary's Campus, London, W2 1PG, UK.; MRC-PHE Centre for Environment and Health, Department of Epidemiology and Biostatistics, Imperial College London, St Mary's Campus, London, W2 1PG, UK., Almgren P; Department of Clinical Sciences, Lund University, Malmö, Sweden., Andersson C; National Heart, Lung, and Blood Institute's and Boston University's Framingham Heart Study, Framingham, MA, USA.; Department of Cardiology, Herlev Gentofte Hospital, Herlev Ringvej 57, 2650, Herlev, Denmark., Aragam KG; Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA, USA., Ärnlöv J; Department of Neurobiology, Care Sciences and Society/ Section of Family Medicine and Primary Care, Karolinska Institutet, Stockholm, Sweden.; School of Health and Social Sciences, Dalarna University, Falun, Sweden., Backman JD; Regeneron Genetics Center, 777 Old Saw Mill River Road, Tarrytown, NY, 10591, USA., Biggs ML; Department of Biostatistics, University of Washington, Seattle, WA, USA.; Department of Medicine, University of Washington, Seattle, WA, USA., Bloom HL; Division of Cardiology, Department of Medicine, Emory University Medical Center, Atlanta, GA, USA., Brandimarto J; Penn Cardiovascular Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Brown MR; Department of Epidemiology, Human Genetics, and Environmental Sciences, The University of Texas School of Public Health, Houston, Texas, USA., Buckbinder L; Pfizer Worldwide Research & Development, 1 Portland St, Cambridge, MA, USA., Carey DJ; Department of Molecular and Functional Genomics, Geisinger, Danville, PA, USA., Chasman DI; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, 02215, USA.; Harvard Medical School, Boston, MA, 02115, USA., Chen X; Pfizer Worldwide Research & Development, 1 Portland St, Cambridge, MA, USA., Chen X; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Chung J; Regeneron Genetics Center, 777 Old Saw Mill River Road, Tarrytown, NY, 10591, USA., Chutkow W; Novartis Institutes for Biomedical Research, Cambridge, MA, USA., Cook JP; Department of Biostatistics, University of Liverpool, Liverpool, UK., Delgado GE; Vth Department of Medicine (Nephrology, Hypertensiology, Endocrinology, Diabetology, Rheumatology), Medical Faculty of Mannheim, University of Heidelberg, Heidelberg, Germany., Denaxas S; British Heart Foundation Research Accelerator, University College London, London, UK.; Institute of Health Informatics, University College London, London, UK.; Health Data Research UK London, University College London, London, UK.; The National Institute for Health Research University College London Hospitals Biomedical Research Centre, University College London, London, UK.; The Alan Turing Institute, London, United Kingdom., Doney AS; Division of Molecular & Clinical Medicine, University of Dundee, Ninewells Hospital and Medical School, Dundee, DD1 9SY, UK., Dörr M; Department of Internal Medicine B, University Medicine Greifswald, Greifswald, Germany.; DZHK (German Center for Cardiovascular Research), partner site Greifswald, Greifswald, Germany., Dudley SC; Cardiovascular Division, Department of Medicine, University of Minnesota, Minneapolis, MN, USA., Dunn ME; Regeneron Pharmaceuticals, Cardiovascular Research, 777 Old Saw Mill River Road, Tarrytown, NY, 10591, USA., Engström G; Department of Clinical Sciences, Lund University, Malmö, Sweden., Esko T; Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu, 51010, Estonia., Felix SB; Department of Internal Medicine B, University Medicine Greifswald, Greifswald, Germany.; DZHK (German Center for Cardiovascular Research), partner site Greifswald, Greifswald, Germany., Finan C; Institute of Cardiovascular Science, University College London, London, UK.; British Heart Foundation Research Accelerator, University College London, London, UK., Ford I; Robertson Center for Biostatistics, University of Glasgow, Glasgow, UK., Ghanbari M; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands., Ghasemi S; DZHK (German Center for Cardiovascular Research), partner site Greifswald, Greifswald, Germany.; Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany., Giedraitis V; Department of Public Health and Caring Sciences, Geriatrics, Uppsala University, Uppsala, 75185, Sweden., Giulianini F; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, 02215, USA., Gottdiener JS; Department of Medicine, Division of Cardiology, University of Maryland School of Medicine, Baltimore, MD, USA., Gross S; Department of Internal Medicine B, University Medicine Greifswald, Greifswald, Germany.; DZHK (German Center for Cardiovascular Research), partner site Greifswald, Greifswald, Germany., Guðbjartsson DF; deCODE genetics/Amgen Inc., Sturlugata 8, 101, Reykjavik, Iceland.; School of Engineering and Natural Sciences, University of Iceland, 101, Reykjavik, Iceland., Gutmann R; Division of Cardiovascular Medicine, University of Iowa Carver College of Medicine, Iowa City, IA, USA., Haggerty CM; Department of Molecular and Functional Genomics, Geisinger, Danville, PA, USA., van der Harst P; Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.; Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.; Durrer Center for Cardiogenetic Research, ICIN-Netherlands Heart Institute, Utrecht, The Netherlands., Hyde CL; Pfizer Worldwide Research & Development, 1 Portland St, Cambridge, MA, USA., Ingelsson E; Department of Medicine, Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA, 94305, USA.; Stanford Cardiovascular Institute, Stanford University, Stanford, CA, 94305, USA.; Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden.; Stanford Diabetes Research Center, Stanford University, Stanford, CA, 94305, USA., Jukema JW; Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands.; Einthoven Laboratory for Experimental Vascular Medicine, LUMC, Leiden, The Netherlands., Kavousi M; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands., Khaw KT; Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB2 0QQ, UK., Kleber ME; Vth Department of Medicine (Nephrology, Hypertensiology, Endocrinology, Diabetology, Rheumatology), Medical Faculty of Mannheim, University of Heidelberg, Heidelberg, Germany., Køber L; Department of Cardiology, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark., Koekemoer A; Department of Cardiovascular Sciences, University of Leicester and NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK., Langenberg C; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge School of Clinical Medicine, Cambridge, CB2 0QQ, UK., Lind L; Department of Medical Sciences, Uppsala University, Uppsala, Sweden., Lindgren CM; Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Big Data Institute at the Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford, UK.; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK., London B; Division of Cardiovascular Medicine and Abboud Cardiovascular Research Center, University of Iowa, Iowa City, IA, USA., Lotta LA; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge School of Clinical Medicine, Cambridge, CB2 0QQ, UK., Lovering RC; Institute of Cardiovascular Science, University College London, London, UK.; British Heart Foundation Research Accelerator, University College London, London, UK., Luan J; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge School of Clinical Medicine, Cambridge, CB2 0QQ, UK., Magnusson P; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Mahajan A; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK., Margulies KB; Penn Cardiovascular Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., März W; Department of Biostatistics, University of Liverpool, Liverpool, UK.; Synlab Academy, Synlab Holding Deutschland GmbH, Mannheim, Germany.; Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Graz, Austria., Melander O; Department of Internal Medicine, Clinical Sciences, Lund University and Skåne University Hospital, Malmö, Sweden., Mordi IR; Division of Molecular & Clinical Medicine, University of Dundee, Ninewells Hospital and Medical School, Dundee, DD1 9SY, UK., Morgan T; Novartis Institutes for Biomedical Research, Cambridge, MA, USA.; Vanderbilt University School of Medicine, Nashville, TN, USA., Morris AD; Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, United Kingdom., Morris AP; Department of Biostatistics, University of Liverpool, Liverpool, UK.; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK., Morrison AC; Department of Epidemiology, Human Genetics, and Environmental Sciences, The University of Texas School of Public Health, Houston, Texas, USA., Nagle MW; Pfizer Worldwide Research & Development, 1 Portland St, Cambridge, MA, USA., Nelson CP; Department of Cardiovascular Sciences, University of Leicester and NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK., Niessner A; Department of Internal Medicine II, Division of Cardiology, Medical University of Vienna, Vienna, Austria., Niiranen T; National Institute for Health and Welfare, Helsinki, Finland.; Department of Medicine, Turku University Hospital and University of Turku, Turku, Finland., O'Donoghue ML; TIMI Study Group, Cardiovascular Division, Brigham and Women's Hospital, Boston, MA, USA., Owens AT; Penn Cardiovascular Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Palmer CNA; Division of Molecular & Clinical Medicine, University of Dundee, Ninewells Hospital and Medical School, Dundee, DD1 9SY, UK., Parry HM; Division of Molecular & Clinical Medicine, University of Dundee, Ninewells Hospital and Medical School, Dundee, DD1 9SY, UK., Perola M; National Institute for Health and Welfare, Helsinki, Finland., Portilla-Fernandez E; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands.; Division of Vascular Medicine and Pharmacology, Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands., Psaty BM; Department of Medicine, Epidemiology, and Health Services, University of Washington, Seattle, WA, USA.; Kaiser Permanente Washington Health Research Institute, Kaiser Permanente Washington, Seattle, WA, USA., Rice KM; Department of Biostatistics, University of Washington, Seattle, WA, USA., Ridker PM; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, 02215, USA.; Harvard Medical School, Boston, MA, 02115, USA., Romaine SPR; Department of Cardiovascular Sciences, University of Leicester and NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK., Rotter JI; The Institute for Translational Genomics and Population Sciences, Departments of Pediatrics and Medicine, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, CA, USA., Salo P; National Institute for Health and Welfare, Helsinki, Finland., Salomaa V; National Institute for Health and Welfare, Helsinki, Finland., van Setten J; Department of Cardiology, Division Heart and Lungs, University Medical Center Utrecht, University of Utrecht, Utrecht, The Netherlands., Shalaby AA; Division of Cardiology, Department of Medicine, University of Pittsburgh Medical Center and VA Pittsburgh HCS, Pittsburgh, PA, USA., Smelser DT; Department of Molecular and Functional Genomics, Geisinger, Danville, PA, USA., Smith NL; Kaiser Permanente Washington Health Research Institute, Kaiser Permanente Washington, Seattle, WA, USA.; Department of Epidemiology, University of Washington, Seattle, WA, USA.; Seattle Epidemiologic Research and Information Center, Department of Veterans Affairs Office of Research & Development, Seattle, WA, USA., Stender S; Department of Clinical Biochemistry, Copenhagen University Hospital, Herlev and Gentofte, København, Denmark., Stott DJ; Institute of Cardiovascular and Medical Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom., Svensson P; Department of Clinical Science and Education, Södersjukhuset, Karolinska Institutet, Stockholm, Sweden.; Department of Cardiology, Södersjukhuset, Stockholm, Sweden., Tammesoo ML; Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu, 51010, Estonia., Taylor KD; Institute for Translational Genomics and Population Sciences, LABiomed and Departments of Pediatrics at Harbor-UCLA Medical Center, Torrance, CA, 90502, USA., Teder-Laving M; Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu, 51010, Estonia., Teumer A; DZHK (German Center for Cardiovascular Research), partner site Greifswald, Greifswald, Germany.; Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany., Thorgeirsson G; deCODE genetics/Amgen Inc., Sturlugata 8, 101, Reykjavik, Iceland.; Division of Cardiology, Department of Internal Medicine, Landspitali, National University Hospital of Iceland, Hringbraut, 101, Reykjavik, Iceland., Thorsteinsdottir U; deCODE genetics/Amgen Inc., Sturlugata 8, 101, Reykjavik, Iceland.; Faculty of Medicine, Department of Medicine, University of Iceland, Saemundargata 2, 101, Reykjavik, Iceland., Torp-Pedersen C; Department of Epidemiology and Biostatistics, Aalborg University Hospital, Aalborg, Denmark.; Department of Health, Science and Technology, Aalborg University Hospital, Aalborg, Denmark.; Departments of Cardiology, Aalborg University Hospital, Aalborg, Denmark., Trompet S; Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands.; Section of Gerontology and Geriatrics, Department of Internal Medicine, Leiden University Medical Center, Leiden, The Netherlands., Tyl B; Translational and Clinical Research, Servier Cardiovascular Center for Therapeutic Innovation, 50 rue Carnot, 92284, Suresnes, France., Uitterlinden AG; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands.; Department of Internal Medicine, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands., Veluchamy A; Division of Molecular & Clinical Medicine, University of Dundee, Ninewells Hospital and Medical School, Dundee, DD1 9SY, UK., Völker U; DZHK (German Center for Cardiovascular Research), partner site Greifswald, Greifswald, Germany.; Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Greifswald, Germany., Voors AA; Section of Computational Biomedicine, Department of Medicine, Boston University School of Medicine, Boston, MA, USA., Wang X; Novartis Institutes for Biomedical Research, Cambridge, MA, USA., Wareham NJ; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge School of Clinical Medicine, Cambridge, CB2 0QQ, UK., Waterworth D; Human Genetics, GlaxoSmithKline, Collegeville, PA, USA., Weeke PE; Department of Cardiology, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark., Weiss R; Division of Cardiovascular Medicine, Department of Internal Medicine, The Ohio State University Medical Center, Columbus, OH, USA., Wiggins KL; Department of Medicine, University of Washington, Seattle, WA, USA., Xing H; Novartis Institutes for Biomedical Research, Cambridge, MA, USA., Yerges-Armstrong LM; Human Genetics, GlaxoSmithKline, Collegeville, PA, USA., Yu B; Department of Epidemiology, Human Genetics, and Environmental Sciences, The University of Texas School of Public Health, Houston, Texas, USA., Zannad F; Université de Lorraine, CHU de Nancy, Inserm and INI-CRCT (F-CRIN), Institut Lorrain du Coeur et des Vaisseaux, 54500, Vandoeuvre Lès, Nancy, France., Zhao JH; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge School of Clinical Medicine, Cambridge, CB2 0QQ, UK., Hemingway H; British Heart Foundation Research Accelerator, University College London, London, UK.; Institute of Health Informatics, University College London, London, UK.; Health Data Research UK London, University College London, London, UK.; BHF Cardiovascular Research Centre, University of Glasgow, Glasgow, United Kingdom., Samani NJ; Department of Cardiovascular Sciences, University of Leicester and NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK., McMurray JJV; BHF Cardiovascular Research Centre, University of Glasgow, Glasgow, United Kingdom., Yang J; Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, 4072, Australia.; Queensland Brain Institute, The University of Queensland, Brisbane, QLD, 4072, Australia., Visscher PM; Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, 4072, Australia.; Queensland Brain Institute, The University of Queensland, Brisbane, QLD, 4072, Australia., Newton-Cheh C; Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA, USA.; Center for Human Genetic Research, Massachusetts General Hospital, Boston, MA, USA., Malarstig A; Cardiovascular Medicine unit, Department of Medicine Solna, Karolinska Institute, Stockholm, Sweden.; Pfizer Worldwide Research & Development, 1 Portland St, Cambridge, MA, USA., Holm H; deCODE genetics/Amgen Inc., Sturlugata 8, 101, Reykjavik, Iceland., Lubitz SA; Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Cardiac Arrhythmia Service and Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA, USA., Sattar N; BHF Cardiovascular Research Centre, University of Glasgow, Glasgow, United Kingdom., Holmes MV; Medical Research Council Population Health Research Unit at the University of Oxford, Oxford, UK.; Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, Big Data Institute, University of Oxford, Oxford, UK.; National Institute for Health Research Oxford Biomedical Research Centre, Oxford University Hospital, Oxford, UK., Cappola TP; Penn Cardiovascular Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Asselbergs FW; Institute of Cardiovascular Science, University College London, London, UK.; British Heart Foundation Research Accelerator, University College London, London, UK.; Department of Cardiology, Division Heart and Lungs, University Medical Center Utrecht, University of Utrecht, Utrecht, The Netherlands., Hingorani AD; Institute of Cardiovascular Science, University College London, London, UK.; British Heart Foundation Research Accelerator, University College London, London, UK., Kuchenbaecker K; Division of Psychiatry, University College of London, London, W1T 7NF, UK.; UCL Genetics Institute, University College London, London, WC1E 6BT, UK., Ellinor PT; Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Cardiac Arrhythmia Service and Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA, USA., Lang CC; Division of Molecular & Clinical Medicine, University of Dundee, Ninewells Hospital and Medical School, Dundee, DD1 9SY, UK., Stefansson K; deCODE genetics/Amgen Inc., Sturlugata 8, 101, Reykjavik, Iceland.; Faculty of Medicine, Department of Medicine, University of Iceland, Saemundargata 2, 101, Reykjavik, Iceland., Smith JG; Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Cardiology, Clinical Sciences, Lund University and Skåne University Hospital, Lund, Sweden.; Wallenberg Center for Molecular Medicine and Lund University Diabetes Center, Lund University, Lund, Sweden., Vasan RS; National Heart, Lung, and Blood Institute's and Boston University's Framingham Heart Study, Framingham, MA, USA.; Sections of Cardiology, Preventive Medicine and Epidemiology, Department of Medicine, Boston University Schools of Medicine and Public Health, Boston, MA, USA., Swerdlow DI; Institute of Cardiovascular Science, University College London, London, UK., Lumbers RT; British Heart Foundation Research Accelerator, University College London, London, UK. t.lumbers@ucl.ac.uk.; Institute of Health Informatics, University College London, London, UK. t.lumbers@ucl.ac.uk.; Health Data Research UK London, University College London, London, UK. t.lumbers@ucl.ac.uk.; Bart's Heart Centre, St. Bartholomew's Hospital, London, UK. t.lumbers@ucl.ac.uk.
Corporate Authors: Regeneron Genetics Center
Source: Nature communications [Nat Commun] 2020 Jan 09; Vol. 11 (1), pp. 163. Date of Electronic Publication: 2020 Jan 09.
Publication Type: Journal Article; Meta-Analysis
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Label: Title
  Group: Ti
  Data: Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure.
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  Label: Authors
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  Data: <searchLink fieldCode="AU" term="%22Shah+S%22">Shah S</searchLink>; Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, 4072, Australia.; Institute of Cardiovascular Science, University College London, London, UK.; British Heart Foundation Research Accelerator, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Henry+A%22">Henry A</searchLink>; Institute of Cardiovascular Science, University College London, London, UK.; British Heart Foundation Research Accelerator, University College London, London, UK.; Institute of Health Informatics, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Roselli+C%22">Roselli C</searchLink>; Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Lin+H%22">Lin H</searchLink>; Section of Computational Biomedicine, Department of Medicine, Boston University School of Medicine, Boston, MA, USA.; National Heart, Lung, and Blood Institute's and Boston University's Framingham Heart Study, Framingham, MA, USA.<br /><searchLink fieldCode="AU" term="%22Sveinbjörnsson+G%22">Sveinbjörnsson G</searchLink>; deCODE genetics/Amgen Inc., Sturlugata 8, 101, Reykjavik, Iceland.<br /><searchLink fieldCode="AU" term="%22Fatemifar+G%22">Fatemifar G</searchLink>; British Heart Foundation Research Accelerator, University College London, London, UK.; Institute of Health Informatics, University College London, London, UK.; Health Data Research UK London, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Hedman+ÅK%22">Hedman ÅK</searchLink>; Cardiovascular Medicine unit, Department of Medicine Solna, Karolinska Institute, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Wilk+JB%22">Wilk JB</searchLink>; Pfizer Worldwide Research & Development, 1 Portland St, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Morley+MP%22">Morley MP</searchLink>; Penn Cardiovascular Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Chaffin+MD%22">Chaffin MD</searchLink>; Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Helgadottir+A%22">Helgadottir A</searchLink>; deCODE genetics/Amgen Inc., Sturlugata 8, 101, Reykjavik, Iceland.<br /><searchLink fieldCode="AU" term="%22Verweij+N%22">Verweij N</searchLink>; Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Dehghan+A%22">Dehghan A</searchLink>; Department of Epidemiology and Biostatistics, Imperial College London, St Mary's Campus, London, W2 1PG, UK.; MRC-PHE Centre for Environment and Health, Department of Epidemiology and Biostatistics, Imperial College London, St Mary's Campus, London, W2 1PG, UK.<br /><searchLink fieldCode="AU" term="%22Almgren+P%22">Almgren P</searchLink>; Department of Clinical Sciences, Lund University, Malmö, Sweden.<br /><searchLink fieldCode="AU" term="%22Andersson+C%22">Andersson C</searchLink>; National Heart, Lung, and Blood Institute's and Boston University's Framingham Heart Study, Framingham, MA, USA.; Department of Cardiology, Herlev Gentofte Hospital, Herlev Ringvej 57, 2650, Herlev, Denmark.<br /><searchLink fieldCode="AU" term="%22Aragam+KG%22">Aragam KG</searchLink>; Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Ärnlöv+J%22">Ärnlöv J</searchLink>; Department of Neurobiology, Care Sciences and Society/ Section of Family Medicine and Primary Care, Karolinska Institutet, Stockholm, Sweden.; School of Health and Social Sciences, Dalarna University, Falun, Sweden.<br /><searchLink fieldCode="AU" term="%22Backman+JD%22">Backman JD</searchLink>; Regeneron Genetics Center, 777 Old Saw Mill River Road, Tarrytown, NY, 10591, USA.<br /><searchLink fieldCode="AU" term="%22Biggs+ML%22">Biggs ML</searchLink>; Department of Biostatistics, University of Washington, Seattle, WA, USA.; Department of Medicine, University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Bloom+HL%22">Bloom HL</searchLink>; Division of Cardiology, Department of Medicine, Emory University Medical Center, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Brandimarto+J%22">Brandimarto J</searchLink>; Penn Cardiovascular Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Brown+MR%22">Brown MR</searchLink>; Department of Epidemiology, Human Genetics, and Environmental Sciences, The University of Texas School of Public Health, Houston, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Buckbinder+L%22">Buckbinder L</searchLink>; Pfizer Worldwide Research & Development, 1 Portland St, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Carey+DJ%22">Carey DJ</searchLink>; Department of Molecular and Functional Genomics, Geisinger, Danville, PA, USA.<br /><searchLink fieldCode="AU" term="%22Chasman+DI%22">Chasman DI</searchLink>; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, 02215, USA.; Harvard Medical School, Boston, MA, 02115, USA.<br /><searchLink fieldCode="AU" term="%22Chen+X%22">Chen X</searchLink>; Pfizer Worldwide Research & Development, 1 Portland St, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Chen+X%22">Chen X</searchLink>; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Chung+J%22">Chung J</searchLink>; Regeneron Genetics Center, 777 Old Saw Mill River Road, Tarrytown, NY, 10591, USA.<br /><searchLink fieldCode="AU" term="%22Chutkow+W%22">Chutkow W</searchLink>; Novartis Institutes for Biomedical Research, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Cook+JP%22">Cook JP</searchLink>; Department of Biostatistics, University of Liverpool, Liverpool, UK.<br /><searchLink fieldCode="AU" term="%22Delgado+GE%22">Delgado GE</searchLink>; Vth Department of Medicine (Nephrology, Hypertensiology, Endocrinology, Diabetology, Rheumatology), Medical Faculty of Mannheim, University of Heidelberg, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Denaxas+S%22">Denaxas S</searchLink>; British Heart Foundation Research Accelerator, University College London, London, UK.; Institute of Health Informatics, University College London, London, UK.; Health Data Research UK London, University College London, London, UK.; The National Institute for Health Research University College London Hospitals Biomedical Research Centre, University College London, London, UK.; The Alan Turing Institute, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Doney+AS%22">Doney AS</searchLink>; Division of Molecular & Clinical Medicine, University of Dundee, Ninewells Hospital and Medical School, Dundee, DD1 9SY, UK.<br /><searchLink fieldCode="AU" term="%22Dörr+M%22">Dörr M</searchLink>; Department of Internal Medicine B, University Medicine Greifswald, Greifswald, Germany.; DZHK (German Center for Cardiovascular Research), partner site Greifswald, Greifswald, Germany.<br /><searchLink fieldCode="AU" term="%22Dudley+SC%22">Dudley SC</searchLink>; Cardiovascular Division, Department of Medicine, University of Minnesota, Minneapolis, MN, USA.<br /><searchLink fieldCode="AU" term="%22Dunn+ME%22">Dunn ME</searchLink>; Regeneron Pharmaceuticals, Cardiovascular Research, 777 Old Saw Mill River Road, Tarrytown, NY, 10591, USA.<br /><searchLink fieldCode="AU" term="%22Engström+G%22">Engström G</searchLink>; Department of Clinical Sciences, Lund University, Malmö, Sweden.<br /><searchLink fieldCode="AU" term="%22Esko+T%22">Esko T</searchLink>; Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu, 51010, Estonia.<br /><searchLink fieldCode="AU" term="%22Felix+SB%22">Felix SB</searchLink>; Department of Internal Medicine B, University Medicine Greifswald, Greifswald, Germany.; DZHK (German Center for Cardiovascular Research), partner site Greifswald, Greifswald, Germany.<br /><searchLink fieldCode="AU" term="%22Finan+C%22">Finan C</searchLink>; Institute of Cardiovascular Science, University College London, London, UK.; British Heart Foundation Research Accelerator, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Ford+I%22">Ford I</searchLink>; Robertson Center for Biostatistics, University of Glasgow, Glasgow, UK.<br /><searchLink fieldCode="AU" term="%22Ghanbari+M%22">Ghanbari M</searchLink>; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Ghasemi+S%22">Ghasemi S</searchLink>; DZHK (German Center for Cardiovascular Research), partner site Greifswald, Greifswald, Germany.; Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany.<br /><searchLink fieldCode="AU" term="%22Giedraitis+V%22">Giedraitis V</searchLink>; Department of Public Health and Caring Sciences, Geriatrics, Uppsala University, Uppsala, 75185, Sweden.<br /><searchLink fieldCode="AU" term="%22Giulianini+F%22">Giulianini F</searchLink>; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, 02215, USA.<br /><searchLink fieldCode="AU" term="%22Gottdiener+JS%22">Gottdiener JS</searchLink>; Department of Medicine, Division of Cardiology, University of Maryland School of Medicine, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Gross+S%22">Gross S</searchLink>; Department of Internal Medicine B, University Medicine Greifswald, Greifswald, Germany.; DZHK (German Center for Cardiovascular Research), partner site Greifswald, Greifswald, Germany.<br /><searchLink fieldCode="AU" term="%22Guðbjartsson+DF%22">Guðbjartsson DF</searchLink>; deCODE genetics/Amgen Inc., Sturlugata 8, 101, Reykjavik, Iceland.; School of Engineering and Natural Sciences, University of Iceland, 101, Reykjavik, Iceland.<br /><searchLink fieldCode="AU" term="%22Gutmann+R%22">Gutmann R</searchLink>; Division of Cardiovascular Medicine, University of Iowa Carver College of Medicine, Iowa City, IA, USA.<br /><searchLink fieldCode="AU" term="%22Haggerty+CM%22">Haggerty CM</searchLink>; Department of Molecular and Functional Genomics, Geisinger, Danville, PA, USA.<br /><searchLink fieldCode="AU" term="%22van+der+Harst+P%22">van der Harst P</searchLink>; Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.; Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.; Durrer Center for Cardiogenetic Research, ICIN-Netherlands Heart Institute, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Hyde+CL%22">Hyde CL</searchLink>; Pfizer Worldwide Research & Development, 1 Portland St, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Ingelsson+E%22">Ingelsson E</searchLink>; Department of Medicine, Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA, 94305, USA.; Stanford Cardiovascular Institute, Stanford University, Stanford, CA, 94305, USA.; Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden.; Stanford Diabetes Research Center, Stanford University, Stanford, CA, 94305, USA.<br /><searchLink fieldCode="AU" term="%22Jukema+JW%22">Jukema JW</searchLink>; Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands.; Einthoven Laboratory for Experimental Vascular Medicine, LUMC, Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Kavousi+M%22">Kavousi M</searchLink>; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Khaw+KT%22">Khaw KT</searchLink>; Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB2 0QQ, UK.<br /><searchLink fieldCode="AU" term="%22Kleber+ME%22">Kleber ME</searchLink>; Vth Department of Medicine (Nephrology, Hypertensiology, Endocrinology, Diabetology, Rheumatology), Medical Faculty of Mannheim, University of Heidelberg, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Køber+L%22">Køber L</searchLink>; Department of Cardiology, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Koekemoer+A%22">Koekemoer A</searchLink>; Department of Cardiovascular Sciences, University of Leicester and NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK.<br /><searchLink fieldCode="AU" term="%22Langenberg+C%22">Langenberg C</searchLink>; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge School of Clinical Medicine, Cambridge, CB2 0QQ, UK.<br /><searchLink fieldCode="AU" term="%22Lind+L%22">Lind L</searchLink>; Department of Medical Sciences, Uppsala University, Uppsala, Sweden.<br /><searchLink fieldCode="AU" term="%22Lindgren+CM%22">Lindgren CM</searchLink>; Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Big Data Institute at the Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford, UK.; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22London+B%22">London B</searchLink>; Division of Cardiovascular Medicine and Abboud Cardiovascular Research Center, University of Iowa, Iowa City, IA, USA.<br /><searchLink fieldCode="AU" term="%22Lotta+LA%22">Lotta LA</searchLink>; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge School of Clinical Medicine, Cambridge, CB2 0QQ, UK.<br /><searchLink fieldCode="AU" term="%22Lovering+RC%22">Lovering RC</searchLink>; Institute of Cardiovascular Science, University College London, London, UK.; British Heart Foundation Research Accelerator, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Luan+J%22">Luan J</searchLink>; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge School of Clinical Medicine, Cambridge, CB2 0QQ, UK.<br /><searchLink fieldCode="AU" term="%22Magnusson+P%22">Magnusson P</searchLink>; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Mahajan+A%22">Mahajan A</searchLink>; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Margulies+KB%22">Margulies KB</searchLink>; Penn Cardiovascular Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22März+W%22">März W</searchLink>; Department of Biostatistics, University of Liverpool, Liverpool, UK.; Synlab Academy, Synlab Holding Deutschland GmbH, Mannheim, Germany.; Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Graz, Austria.<br /><searchLink fieldCode="AU" term="%22Melander+O%22">Melander O</searchLink>; Department of Internal Medicine, Clinical Sciences, Lund University and Skåne University Hospital, Malmö, Sweden.<br /><searchLink fieldCode="AU" term="%22Mordi+IR%22">Mordi IR</searchLink>; Division of Molecular & Clinical Medicine, University of Dundee, Ninewells Hospital and Medical School, Dundee, DD1 9SY, UK.<br /><searchLink fieldCode="AU" term="%22Morgan+T%22">Morgan T</searchLink>; Novartis Institutes for Biomedical Research, Cambridge, MA, USA.; Vanderbilt University School of Medicine, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Morris+AD%22">Morris AD</searchLink>; Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Morris+AP%22">Morris AP</searchLink>; Department of Biostatistics, University of Liverpool, Liverpool, UK.; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Morrison+AC%22">Morrison AC</searchLink>; Department of Epidemiology, Human Genetics, and Environmental Sciences, The University of Texas School of Public Health, Houston, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Nagle+MW%22">Nagle MW</searchLink>; Pfizer Worldwide Research & Development, 1 Portland St, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Nelson+CP%22">Nelson CP</searchLink>; Department of Cardiovascular Sciences, University of Leicester and NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK.<br /><searchLink fieldCode="AU" term="%22Niessner+A%22">Niessner A</searchLink>; Department of Internal Medicine II, Division of Cardiology, Medical University of Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Niiranen+T%22">Niiranen T</searchLink>; National Institute for Health and Welfare, Helsinki, Finland.; Department of Medicine, Turku University Hospital and University of Turku, Turku, Finland.<br /><searchLink fieldCode="AU" term="%22O'Donoghue+ML%22">O'Donoghue ML</searchLink>; TIMI Study Group, Cardiovascular Division, Brigham and Women's Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Owens+AT%22">Owens AT</searchLink>; Penn Cardiovascular Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Palmer+CNA%22">Palmer CNA</searchLink>; Division of Molecular & Clinical Medicine, University of Dundee, Ninewells Hospital and Medical School, Dundee, DD1 9SY, UK.<br /><searchLink fieldCode="AU" term="%22Parry+HM%22">Parry HM</searchLink>; Division of Molecular & Clinical Medicine, University of Dundee, Ninewells Hospital and Medical School, Dundee, DD1 9SY, UK.<br /><searchLink fieldCode="AU" term="%22Perola+M%22">Perola M</searchLink>; National Institute for Health and Welfare, Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Portilla-Fernandez+E%22">Portilla-Fernandez E</searchLink>; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands.; Division of Vascular Medicine and Pharmacology, Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Psaty+BM%22">Psaty BM</searchLink>; Department of Medicine, Epidemiology, and Health Services, University of Washington, Seattle, WA, USA.; Kaiser Permanente Washington Health Research Institute, Kaiser Permanente Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Rice+KM%22">Rice KM</searchLink>; Department of Biostatistics, University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Ridker+PM%22">Ridker PM</searchLink>; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, 02215, USA.; Harvard Medical School, Boston, MA, 02115, USA.<br /><searchLink fieldCode="AU" term="%22Romaine+SPR%22">Romaine SPR</searchLink>; Department of Cardiovascular Sciences, University of Leicester and NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK.<br /><searchLink fieldCode="AU" term="%22Rotter+JI%22">Rotter JI</searchLink>; The Institute for Translational Genomics and Population Sciences, Departments of Pediatrics and Medicine, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, CA, USA.<br /><searchLink fieldCode="AU" term="%22Salo+P%22">Salo P</searchLink>; National Institute for Health and Welfare, Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Salomaa+V%22">Salomaa V</searchLink>; National Institute for Health and Welfare, Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22van+Setten+J%22">van Setten J</searchLink>; Department of Cardiology, Division Heart and Lungs, University Medical Center Utrecht, University of Utrecht, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Shalaby+AA%22">Shalaby AA</searchLink>; Division of Cardiology, Department of Medicine, University of Pittsburgh Medical Center and VA Pittsburgh HCS, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Smelser+DT%22">Smelser DT</searchLink>; Department of Molecular and Functional Genomics, Geisinger, Danville, PA, USA.<br /><searchLink fieldCode="AU" term="%22Smith+NL%22">Smith NL</searchLink>; Kaiser Permanente Washington Health Research Institute, Kaiser Permanente Washington, Seattle, WA, USA.; Department of Epidemiology, University of Washington, Seattle, WA, USA.; Seattle Epidemiologic Research and Information Center, Department of Veterans Affairs Office of Research & Development, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Stender+S%22">Stender S</searchLink>; Department of Clinical Biochemistry, Copenhagen University Hospital, Herlev and Gentofte, København, Denmark.<br /><searchLink fieldCode="AU" term="%22Stott+DJ%22">Stott DJ</searchLink>; Institute of Cardiovascular and Medical Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Svensson+P%22">Svensson P</searchLink>; Department of Clinical Science and Education, Södersjukhuset, Karolinska Institutet, Stockholm, Sweden.; Department of Cardiology, Södersjukhuset, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Tammesoo+ML%22">Tammesoo ML</searchLink>; Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu, 51010, Estonia.<br /><searchLink fieldCode="AU" term="%22Taylor+KD%22">Taylor KD</searchLink>; Institute for Translational Genomics and Population Sciences, LABiomed and Departments of Pediatrics at Harbor-UCLA Medical Center, Torrance, CA, 90502, USA.<br /><searchLink fieldCode="AU" term="%22Teder-Laving+M%22">Teder-Laving M</searchLink>; Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu, 51010, Estonia.<br /><searchLink fieldCode="AU" term="%22Teumer+A%22">Teumer A</searchLink>; DZHK (German Center for Cardiovascular Research), partner site Greifswald, Greifswald, Germany.; Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany.<br /><searchLink fieldCode="AU" term="%22Thorgeirsson+G%22">Thorgeirsson G</searchLink>; deCODE genetics/Amgen Inc., Sturlugata 8, 101, Reykjavik, Iceland.; Division of Cardiology, Department of Internal Medicine, Landspitali, National University Hospital of Iceland, Hringbraut, 101, Reykjavik, Iceland.<br /><searchLink fieldCode="AU" term="%22Thorsteinsdottir+U%22">Thorsteinsdottir U</searchLink>; deCODE genetics/Amgen Inc., Sturlugata 8, 101, Reykjavik, Iceland.; Faculty of Medicine, Department of Medicine, University of Iceland, Saemundargata 2, 101, Reykjavik, Iceland.<br /><searchLink fieldCode="AU" term="%22Torp-Pedersen+C%22">Torp-Pedersen C</searchLink>; Department of Epidemiology and Biostatistics, Aalborg University Hospital, Aalborg, Denmark.; Department of Health, Science and Technology, Aalborg University Hospital, Aalborg, Denmark.; Departments of Cardiology, Aalborg University Hospital, Aalborg, Denmark.<br /><searchLink fieldCode="AU" term="%22Trompet+S%22">Trompet S</searchLink>; Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands.; Section of Gerontology and Geriatrics, Department of Internal Medicine, Leiden University Medical Center, Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Tyl+B%22">Tyl B</searchLink>; Translational and Clinical Research, Servier Cardiovascular Center for Therapeutic Innovation, 50 rue Carnot, 92284, Suresnes, France.<br /><searchLink fieldCode="AU" term="%22Uitterlinden+AG%22">Uitterlinden AG</searchLink>; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands.; Department of Internal Medicine, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Veluchamy+A%22">Veluchamy A</searchLink>; Division of Molecular & Clinical Medicine, University of Dundee, Ninewells Hospital and Medical School, Dundee, DD1 9SY, UK.<br /><searchLink fieldCode="AU" term="%22Völker+U%22">Völker U</searchLink>; DZHK (German Center for Cardiovascular Research), partner site Greifswald, Greifswald, Germany.; Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Greifswald, Germany.<br /><searchLink fieldCode="AU" term="%22Voors+AA%22">Voors AA</searchLink>; Section of Computational Biomedicine, Department of Medicine, Boston University School of Medicine, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Wang+X%22">Wang X</searchLink>; Novartis Institutes for Biomedical Research, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Wareham+NJ%22">Wareham NJ</searchLink>; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge School of Clinical Medicine, Cambridge, CB2 0QQ, UK.<br /><searchLink fieldCode="AU" term="%22Waterworth+D%22">Waterworth D</searchLink>; Human Genetics, GlaxoSmithKline, Collegeville, PA, USA.<br /><searchLink fieldCode="AU" term="%22Weeke+PE%22">Weeke PE</searchLink>; Department of Cardiology, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Weiss+R%22">Weiss R</searchLink>; Division of Cardiovascular Medicine, Department of Internal Medicine, The Ohio State University Medical Center, Columbus, OH, USA.<br /><searchLink fieldCode="AU" term="%22Wiggins+KL%22">Wiggins KL</searchLink>; Department of Medicine, University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Xing+H%22">Xing H</searchLink>; Novartis Institutes for Biomedical Research, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Yerges-Armstrong+LM%22">Yerges-Armstrong LM</searchLink>; Human Genetics, GlaxoSmithKline, Collegeville, PA, USA.<br /><searchLink fieldCode="AU" term="%22Yu+B%22">Yu B</searchLink>; Department of Epidemiology, Human Genetics, and Environmental Sciences, The University of Texas School of Public Health, Houston, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Zannad+F%22">Zannad F</searchLink>; Université de Lorraine, CHU de Nancy, Inserm and INI-CRCT (F-CRIN), Institut Lorrain du Coeur et des Vaisseaux, 54500, Vandoeuvre Lès, Nancy, France.<br /><searchLink fieldCode="AU" term="%22Zhao+JH%22">Zhao JH</searchLink>; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge School of Clinical Medicine, Cambridge, CB2 0QQ, UK.<br /><searchLink fieldCode="AU" term="%22Hemingway+H%22">Hemingway H</searchLink>; British Heart Foundation Research Accelerator, University College London, London, UK.; Institute of Health Informatics, University College London, London, UK.; Health Data Research UK London, University College London, London, UK.; BHF Cardiovascular Research Centre, University of Glasgow, Glasgow, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Samani+NJ%22">Samani NJ</searchLink>; Department of Cardiovascular Sciences, University of Leicester and NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK.<br /><searchLink fieldCode="AU" term="%22McMurray+JJV%22">McMurray JJV</searchLink>; BHF Cardiovascular Research Centre, University of Glasgow, Glasgow, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Yang+J%22">Yang J</searchLink>; Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, 4072, Australia.; Queensland Brain Institute, The University of Queensland, Brisbane, QLD, 4072, Australia.<br /><searchLink fieldCode="AU" term="%22Visscher+PM%22">Visscher PM</searchLink>; Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, 4072, Australia.; Queensland Brain Institute, The University of Queensland, Brisbane, QLD, 4072, Australia.<br /><searchLink fieldCode="AU" term="%22Newton-Cheh+C%22">Newton-Cheh C</searchLink>; Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA, USA.; Center for Human Genetic Research, Massachusetts General Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Malarstig+A%22">Malarstig A</searchLink>; Cardiovascular Medicine unit, Department of Medicine Solna, Karolinska Institute, Stockholm, Sweden.; Pfizer Worldwide Research & Development, 1 Portland St, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Holm+H%22">Holm H</searchLink>; deCODE genetics/Amgen Inc., Sturlugata 8, 101, Reykjavik, Iceland.<br /><searchLink fieldCode="AU" term="%22Lubitz+SA%22">Lubitz SA</searchLink>; Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Cardiac Arrhythmia Service and Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Sattar+N%22">Sattar N</searchLink>; BHF Cardiovascular Research Centre, University of Glasgow, Glasgow, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Holmes+MV%22">Holmes MV</searchLink>; Medical Research Council Population Health Research Unit at the University of Oxford, Oxford, UK.; Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, Big Data Institute, University of Oxford, Oxford, UK.; National Institute for Health Research Oxford Biomedical Research Centre, Oxford University Hospital, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Cappola+TP%22">Cappola TP</searchLink>; Penn Cardiovascular Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Asselbergs+FW%22">Asselbergs FW</searchLink>; Institute of Cardiovascular Science, University College London, London, UK.; British Heart Foundation Research Accelerator, University College London, London, UK.; Department of Cardiology, Division Heart and Lungs, University Medical Center Utrecht, University of Utrecht, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Hingorani+AD%22">Hingorani AD</searchLink>; Institute of Cardiovascular Science, University College London, London, UK.; British Heart Foundation Research Accelerator, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Kuchenbaecker+K%22">Kuchenbaecker K</searchLink>; Division of Psychiatry, University College of London, London, W1T 7NF, UK.; UCL Genetics Institute, University College London, London, WC1E 6BT, UK.<br /><searchLink fieldCode="AU" term="%22Ellinor+PT%22">Ellinor PT</searchLink>; Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Cardiac Arrhythmia Service and Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Lang+CC%22">Lang CC</searchLink>; Division of Molecular & Clinical Medicine, University of Dundee, Ninewells Hospital and Medical School, Dundee, DD1 9SY, UK.<br /><searchLink fieldCode="AU" term="%22Stefansson+K%22">Stefansson K</searchLink>; deCODE genetics/Amgen Inc., Sturlugata 8, 101, Reykjavik, Iceland.; Faculty of Medicine, Department of Medicine, University of Iceland, Saemundargata 2, 101, Reykjavik, Iceland.<br /><searchLink fieldCode="AU" term="%22Smith+JG%22">Smith JG</searchLink>; Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Cardiology, Clinical Sciences, Lund University and Skåne University Hospital, Lund, Sweden.; Wallenberg Center for Molecular Medicine and Lund University Diabetes Center, Lund University, Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Vasan+RS%22">Vasan RS</searchLink>; National Heart, Lung, and Blood Institute's and Boston University's Framingham Heart Study, Framingham, MA, USA.; Sections of Cardiology, Preventive Medicine and Epidemiology, Department of Medicine, Boston University Schools of Medicine and Public Health, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Swerdlow+DI%22">Swerdlow DI</searchLink>; Institute of Cardiovascular Science, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Lumbers+RT%22">Lumbers RT</searchLink>; British Heart Foundation Research Accelerator, University College London, London, UK. t.lumbers@ucl.ac.uk.; Institute of Health Informatics, University College London, London, UK. t.lumbers@ucl.ac.uk.; Health Data Research UK London, University College London, London, UK. t.lumbers@ucl.ac.uk.; Bart's Heart Centre, St. Bartholomew's Hospital, London, UK. t.lumbers@ucl.ac.uk.
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  Data: <searchLink fieldCode="CA" term="%22Regeneron+Genetics+Center%22">Regeneron Genetics Center</searchLink>
– Name: TitleSource
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  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2020 Jan 09; Vol. 11 (1), pp. 163. <i>Date of Electronic Publication: </i>2020 Jan 09.
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  Label: Publication Type
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  Data: Journal Article; Meta-Analysis
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  Label: Journal Info
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Pub%2E+Group%22">Nature Pub. Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101528555 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2041-1723 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220411723%22">20411723 </searchLink><i>NLM ISO Abbreviation: </i>Nat Commun <i>Subsets: </i>MEDLINE
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      – Type: doi
        Value: 10.1038/s41467-019-13690-5
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      – Code: eng
        Text: English
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        StartPage: 163
    Titles:
      – TitleFull: Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure.
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            – D: 09
              M: 01
              Text: 2020 Jan 09
              Type: published
              Y: 2020
          Identifiers:
            – Type: issn-electronic
              Value: 2041-1723
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              Value: 11
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            – TitleFull: Nature communications
              Type: main
ResultId 1