Cancer Neoepitopes for Immunotherapy: Discordance Between Tumor-Infiltrating T Cell Reactivity and Tumor MHC Peptidome Display.

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Title: Cancer Neoepitopes for Immunotherapy: Discordance Between Tumor-Infiltrating T Cell Reactivity and Tumor MHC Peptidome Display.
Authors: Wickström SL; Department of Oncology and Pathology, Karolinska Institutet, Stockholm, Sweden., Lövgren T; Department of Oncology and Pathology, Karolinska Institutet, Stockholm, Sweden.; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden., Volkmar M; Division of Molecular Oncology of Gastrointestinal Tumors, German Cancer Research Center (DKFZ), Heidelberg, Germany., Reinhold B; Laboratory of Immunobiology, Dana-Farber Cancer Institute, Boston, MA, United States.; Department of Medical Oncology, Dana-Farber Cancer Institute and Department of Medicine, Harvard Medical School, Boston, MA, United States., Duke-Cohan JS; Laboratory of Immunobiology, Dana-Farber Cancer Institute, Boston, MA, United States.; Department of Medical Oncology, Dana-Farber Cancer Institute and Department of Medicine, Harvard Medical School, Boston, MA, United States., Hartmann L; Department of Oncology and Pathology, Karolinska Institutet, Stockholm, Sweden., Rebmann J; Division of Molecular Oncology of Gastrointestinal Tumors, German Cancer Research Center (DKFZ), Heidelberg, Germany., Mueller A; Institute of Medical Immunology, Martin Luther University Halle-Wittenberg, Halle, Germany., Melief J; Department of Oncology and Pathology, Karolinska Institutet, Stockholm, Sweden., Maas R; Department of Oncology and Pathology, Karolinska Institutet, Stockholm, Sweden., Ligtenberg M; Department of Oncology and Pathology, Karolinska Institutet, Stockholm, Sweden., Hansson J; Department of Oncology and Pathology, Karolinska Institutet, Stockholm, Sweden., Offringa R; Division of Molecular Oncology of Gastrointestinal Tumors, German Cancer Research Center (DKFZ), Heidelberg, Germany., Seliger B; Institute of Medical Immunology, Martin Luther University Halle-Wittenberg, Halle, Germany., Poschke I; Division of Molecular Oncology of Gastrointestinal Tumors, German Cancer Research Center (DKFZ), Heidelberg, Germany.; DKTK Immune Monitoring Unit, German Cancer Research Center (DKFZ) and National Center for Tumor Diseases (NCT), Heidelberg, Germany., Reinherz EL; Laboratory of Immunobiology, Dana-Farber Cancer Institute, Boston, MA, United States.; Department of Medical Oncology, Dana-Farber Cancer Institute and Department of Medicine, Harvard Medical School, Boston, MA, United States., Kiessling R; Department of Oncology and Pathology, Karolinska Institutet, Stockholm, Sweden.
Source: Frontiers in immunology [Front Immunol] 2019 Dec 11; Vol. 10, pp. 2766. Date of Electronic Publication: 2019 Dec 11 (Print Publication: 2019).
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
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  Data: Cancer Neoepitopes for Immunotherapy: Discordance Between Tumor-Infiltrating T Cell Reactivity and Tumor MHC Peptidome Display.
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  Data: <searchLink fieldCode="AU" term="%22Wickström+SL%22">Wickström SL</searchLink>; Department of Oncology and Pathology, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Lövgren+T%22">Lövgren T</searchLink>; Department of Oncology and Pathology, Karolinska Institutet, Stockholm, Sweden.; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden.<br /><searchLink fieldCode="AU" term="%22Volkmar+M%22">Volkmar M</searchLink>; Division of Molecular Oncology of Gastrointestinal Tumors, German Cancer Research Center (DKFZ), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Reinhold+B%22">Reinhold B</searchLink>; Laboratory of Immunobiology, Dana-Farber Cancer Institute, Boston, MA, United States.; Department of Medical Oncology, Dana-Farber Cancer Institute and Department of Medicine, Harvard Medical School, Boston, MA, United States.<br /><searchLink fieldCode="AU" term="%22Duke-Cohan+JS%22">Duke-Cohan JS</searchLink>; Laboratory of Immunobiology, Dana-Farber Cancer Institute, Boston, MA, United States.; Department of Medical Oncology, Dana-Farber Cancer Institute and Department of Medicine, Harvard Medical School, Boston, MA, United States.<br /><searchLink fieldCode="AU" term="%22Hartmann+L%22">Hartmann L</searchLink>; Department of Oncology and Pathology, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Rebmann+J%22">Rebmann J</searchLink>; Division of Molecular Oncology of Gastrointestinal Tumors, German Cancer Research Center (DKFZ), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Mueller+A%22">Mueller A</searchLink>; Institute of Medical Immunology, Martin Luther University Halle-Wittenberg, Halle, Germany.<br /><searchLink fieldCode="AU" term="%22Melief+J%22">Melief J</searchLink>; Department of Oncology and Pathology, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Maas+R%22">Maas R</searchLink>; Department of Oncology and Pathology, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Ligtenberg+M%22">Ligtenberg M</searchLink>; Department of Oncology and Pathology, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Hansson+J%22">Hansson J</searchLink>; Department of Oncology and Pathology, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Offringa+R%22">Offringa R</searchLink>; Division of Molecular Oncology of Gastrointestinal Tumors, German Cancer Research Center (DKFZ), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Seliger+B%22">Seliger B</searchLink>; Institute of Medical Immunology, Martin Luther University Halle-Wittenberg, Halle, Germany.<br /><searchLink fieldCode="AU" term="%22Poschke+I%22">Poschke I</searchLink>; Division of Molecular Oncology of Gastrointestinal Tumors, German Cancer Research Center (DKFZ), Heidelberg, Germany.; DKTK Immune Monitoring Unit, German Cancer Research Center (DKFZ) and National Center for Tumor Diseases (NCT), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Reinherz+EL%22">Reinherz EL</searchLink>; Laboratory of Immunobiology, Dana-Farber Cancer Institute, Boston, MA, United States.; Department of Medical Oncology, Dana-Farber Cancer Institute and Department of Medicine, Harvard Medical School, Boston, MA, United States.<br /><searchLink fieldCode="AU" term="%22Kiessling+R%22">Kiessling R</searchLink>; Department of Oncology and Pathology, Karolinska Institutet, Stockholm, Sweden.
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