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An Agent-Based Systems Pharmacology Model of the Antibody-Drug Conjugate Kadcyla to Predict Efficacy of Different Dosing Regimens.

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Title: An Agent-Based Systems Pharmacology Model of the Antibody-Drug Conjugate Kadcyla to Predict Efficacy of Different Dosing Regimens.
Authors: Menezes B; Department of Chemical Engineering, University of Michigan, NCRC B28, 2800 Plymouth Road, Ann Arbor, Michigan, 48109-2800, USA., Cilliers C; Department of Chemical Engineering, University of Michigan, NCRC B28, 2800 Plymouth Road, Ann Arbor, Michigan, 48109-2800, USA., Wessler T; Department of Chemical Engineering, University of Michigan, NCRC B28, 2800 Plymouth Road, Ann Arbor, Michigan, 48109-2800, USA., Thurber GM; Department of Chemical Engineering, University of Michigan, NCRC B28, 2800 Plymouth Road, Ann Arbor, Michigan, 48109-2800, USA.; Department of Biomedical Engineering, University of Michigan, Ann Arbor, Michigan, 48109, USA., Linderman JJ; Department of Chemical Engineering, University of Michigan, NCRC B28, 2800 Plymouth Road, Ann Arbor, Michigan, 48109-2800, USA. linderma@umich.edu.; Department of Biomedical Engineering, University of Michigan, Ann Arbor, Michigan, 48109, USA. linderma@umich.edu.
Source: The AAPS journal [AAPS J] 2020 Jan 15; Vol. 22 (2), pp. 29. Date of Electronic Publication: 2020 Jan 15.
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: American Association of Pharmaceutical Scientists Country of Publication: United States NLM ID: 101223209 Publication Model: Electronic Cited Medium: Internet ISSN: 1550-7416 (Electronic) Linking ISSN: 15507416 NLM ISO Abbreviation: AAPS J Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: An Agent-Based Systems Pharmacology Model of the Antibody-Drug Conjugate Kadcyla to Predict Efficacy of Different Dosing Regimens.
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  Data: <searchLink fieldCode="AU" term="%22Menezes+B%22">Menezes B</searchLink>; Department of Chemical Engineering, University of Michigan, NCRC B28, 2800 Plymouth Road, Ann Arbor, Michigan, 48109-2800, USA.<br /><searchLink fieldCode="AU" term="%22Cilliers+C%22">Cilliers C</searchLink>; Department of Chemical Engineering, University of Michigan, NCRC B28, 2800 Plymouth Road, Ann Arbor, Michigan, 48109-2800, USA.<br /><searchLink fieldCode="AU" term="%22Wessler+T%22">Wessler T</searchLink>; Department of Chemical Engineering, University of Michigan, NCRC B28, 2800 Plymouth Road, Ann Arbor, Michigan, 48109-2800, USA.<br /><searchLink fieldCode="AU" term="%22Thurber+GM%22">Thurber GM</searchLink>; Department of Chemical Engineering, University of Michigan, NCRC B28, 2800 Plymouth Road, Ann Arbor, Michigan, 48109-2800, USA.; Department of Biomedical Engineering, University of Michigan, Ann Arbor, Michigan, 48109, USA.<br /><searchLink fieldCode="AU" term="%22Linderman+JJ%22">Linderman JJ</searchLink>; Department of Chemical Engineering, University of Michigan, NCRC B28, 2800 Plymouth Road, Ann Arbor, Michigan, 48109-2800, USA. linderma@umich.edu.; Department of Biomedical Engineering, University of Michigan, Ann Arbor, Michigan, 48109, USA. linderma@umich.edu.
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  Data: <searchLink fieldCode="JN" term="%22101223209%22">The AAPS journal</searchLink> [AAPS J] 2020 Jan 15; Vol. 22 (2), pp. 29. <i>Date of Electronic Publication: </i>2020 Jan 15.
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        Value: 10.1208/s12248-019-0391-1
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