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Candidate Cancer Driver Mutations in Distal Regulatory Elements and Long-Range Chromatin Interaction Networks.

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Title: Candidate Cancer Driver Mutations in Distal Regulatory Elements and Long-Range Chromatin Interaction Networks.
Authors: Zhu H; Computational Biology Program, Ontario Institute for Cancer Research, 661 University Avenue Suite 510, Toronto, ON M5G 0A3, Canada; Department of Medical Biophysics, University of Toronto, 101 College Street Suite 15-701, Toronto, ON M5G 1L7, Canada., Uusküla-Reimand L; Program in Genetics and Genome Biology, SickKids Research Institute, Peter Gilgan Centre for Research and Learning (PGCRL), 686 Bay Street, Toronto, ON M5G 0A4, Canada; Division of Gene Technology, Department of Chemistry and Biotechnology, Tallinn University of Technology, Akadeemia tee 15, Tallinn 12618, Estonia., Isaev K; Computational Biology Program, Ontario Institute for Cancer Research, 661 University Avenue Suite 510, Toronto, ON M5G 0A3, Canada; Department of Medical Biophysics, University of Toronto, 101 College Street Suite 15-701, Toronto, ON M5G 1L7, Canada., Wadi L; Computational Biology Program, Ontario Institute for Cancer Research, 661 University Avenue Suite 510, Toronto, ON M5G 0A3, Canada., Alizada A; Program in Genetics and Genome Biology, SickKids Research Institute, Peter Gilgan Centre for Research and Learning (PGCRL), 686 Bay Street, Toronto, ON M5G 0A4, Canada., Shuai S; Computational Biology Program, Ontario Institute for Cancer Research, 661 University Avenue Suite 510, Toronto, ON M5G 0A3, Canada; Department of Molecular Genetics, University of Toronto, 1 King's College Circle, Toronto, ON M5S 1A8, Canada., Huang V; Computational Biology Program, Ontario Institute for Cancer Research, 661 University Avenue Suite 510, Toronto, ON M5G 0A3, Canada., Aduluso-Nwaobasi D; Computational Biology Program, Ontario Institute for Cancer Research, 661 University Avenue Suite 510, Toronto, ON M5G 0A3, Canada., Paczkowska M; Computational Biology Program, Ontario Institute for Cancer Research, 661 University Avenue Suite 510, Toronto, ON M5G 0A3, Canada., Abd-Rabbo D; Computational Biology Program, Ontario Institute for Cancer Research, 661 University Avenue Suite 510, Toronto, ON M5G 0A3, Canada., Ocsenas O; Computational Biology Program, Ontario Institute for Cancer Research, 661 University Avenue Suite 510, Toronto, ON M5G 0A3, Canada; Department of Medical Biophysics, University of Toronto, 101 College Street Suite 15-701, Toronto, ON M5G 1L7, Canada., Liang M; Program in Genetics and Genome Biology, SickKids Research Institute, Peter Gilgan Centre for Research and Learning (PGCRL), 686 Bay Street, Toronto, ON M5G 0A4, Canada; Department of Molecular Genetics, University of Toronto, 1 King's College Circle, Toronto, ON M5S 1A8, Canada., Thompson JD; Computational Biology Program, Ontario Institute for Cancer Research, 661 University Avenue Suite 510, Toronto, ON M5G 0A3, Canada., Li Y; Computational Biology Program, Ontario Institute for Cancer Research, 661 University Avenue Suite 510, Toronto, ON M5G 0A3, Canada., Ruan L; Computational Biology Program, Ontario Institute for Cancer Research, 661 University Avenue Suite 510, Toronto, ON M5G 0A3, Canada., Krassowski M; Computational Biology Program, Ontario Institute for Cancer Research, 661 University Avenue Suite 510, Toronto, ON M5G 0A3, Canada., Dzneladze I; Computational Biology Program, Ontario Institute for Cancer Research, 661 University Avenue Suite 510, Toronto, ON M5G 0A3, Canada., Simpson JT; Computational Biology Program, Ontario Institute for Cancer Research, 661 University Avenue Suite 510, Toronto, ON M5G 0A3, Canada; Department of Computer Science, University of Toronto, 214 College Street, Toronto, ON M5T 3A1, Canada., Lupien M; Department of Medical Biophysics, University of Toronto, 101 College Street Suite 15-701, Toronto, ON M5G 1L7, Canada; Princess Margaret Cancer Centre, 101 College Street, Toronto, ON M5G 0A3, Canada., Stein LD; Computational Biology Program, Ontario Institute for Cancer Research, 661 University Avenue Suite 510, Toronto, ON M5G 0A3, Canada; Department of Molecular Genetics, University of Toronto, 1 King's College Circle, Toronto, ON M5S 1A8, Canada., Boutros PC; Department of Medical Biophysics, University of Toronto, 101 College Street Suite 15-701, Toronto, ON M5G 1L7, Canada; Department of Human Genetics, University of California Los Angeles, 10833 Le Conte Avenue, Los Angeles, CA 90095, USA; Department of Urology, University of California Los Angeles, 200 Medical Plaza Driveway #140, Los Angeles, CA 90024, USA; Institute of Precision Health, University of California Los Angeles, 10833 Le Conte Avenue, Los Angeles, CA 90024, USA; Jonsson Comprehensive Cancer Centre, University of California Los Angeles, 10833 Le Conte Avenue, Los Angeles, CA 90024, USA., Wilson MD; Program in Genetics and Genome Biology, SickKids Research Institute, Peter Gilgan Centre for Research and Learning (PGCRL), 686 Bay Street, Toronto, ON M5G 0A4, Canada; Department of Molecular Genetics, University of Toronto, 1 King's College Circle, Toronto, ON M5S 1A8, Canada., Reimand J; Computational Biology Program, Ontario Institute for Cancer Research, 661 University Avenue Suite 510, Toronto, ON M5G 0A3, Canada; Department of Medical Biophysics, University of Toronto, 101 College Street Suite 15-701, Toronto, ON M5G 1L7, Canada. Electronic address: juri.reimand@utoronto.ca.
Source: Molecular cell [Mol Cell] 2020 Mar 19; Vol. 77 (6), pp. 1307-1321.e10. Date of Electronic Publication: 2020 Jan 17.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 9802571 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4164 (Electronic) Linking ISSN: 10972765 NLM ISO Abbreviation: Mol Cell Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
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  Data: Candidate Cancer Driver Mutations in Distal Regulatory Elements and Long-Range Chromatin Interaction Networks.
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  Data: <searchLink fieldCode="AU" term="%22Zhu+H%22">Zhu H</searchLink>; Computational Biology Program, Ontario Institute for Cancer Research, 661 University Avenue Suite 510, Toronto, ON M5G 0A3, Canada; Department of Medical Biophysics, University of Toronto, 101 College Street Suite 15-701, Toronto, ON M5G 1L7, Canada.<br /><searchLink fieldCode="AU" term="%22Uusküla-Reimand+L%22">Uusküla-Reimand L</searchLink>; Program in Genetics and Genome Biology, SickKids Research Institute, Peter Gilgan Centre for Research and Learning (PGCRL), 686 Bay Street, Toronto, ON M5G 0A4, Canada; Division of Gene Technology, Department of Chemistry and Biotechnology, Tallinn University of Technology, Akadeemia tee 15, Tallinn 12618, Estonia.<br /><searchLink fieldCode="AU" term="%22Isaev+K%22">Isaev K</searchLink>; Computational Biology Program, Ontario Institute for Cancer Research, 661 University Avenue Suite 510, Toronto, ON M5G 0A3, Canada; Department of Medical Biophysics, University of Toronto, 101 College Street Suite 15-701, Toronto, ON M5G 1L7, Canada.<br /><searchLink fieldCode="AU" term="%22Wadi+L%22">Wadi L</searchLink>; Computational Biology Program, Ontario Institute for Cancer Research, 661 University Avenue Suite 510, Toronto, ON M5G 0A3, Canada.<br /><searchLink fieldCode="AU" term="%22Alizada+A%22">Alizada A</searchLink>; Program in Genetics and Genome Biology, SickKids Research Institute, Peter Gilgan Centre for Research and Learning (PGCRL), 686 Bay Street, Toronto, ON M5G 0A4, Canada.<br /><searchLink fieldCode="AU" term="%22Shuai+S%22">Shuai S</searchLink>; Computational Biology Program, Ontario Institute for Cancer Research, 661 University Avenue Suite 510, Toronto, ON M5G 0A3, Canada; Department of Molecular Genetics, University of Toronto, 1 King's College Circle, Toronto, ON M5S 1A8, Canada.<br /><searchLink fieldCode="AU" term="%22Huang+V%22">Huang V</searchLink>; Computational Biology Program, Ontario Institute for Cancer Research, 661 University Avenue Suite 510, Toronto, ON M5G 0A3, Canada.<br /><searchLink fieldCode="AU" term="%22Aduluso-Nwaobasi+D%22">Aduluso-Nwaobasi D</searchLink>; 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Department of Molecular Genetics, University of Toronto, 1 King's College Circle, Toronto, ON M5S 1A8, Canada.<br /><searchLink fieldCode="AU" term="%22Thompson+JD%22">Thompson JD</searchLink>; Computational Biology Program, Ontario Institute for Cancer Research, 661 University Avenue Suite 510, Toronto, ON M5G 0A3, Canada.<br /><searchLink fieldCode="AU" term="%22Li+Y%22">Li Y</searchLink>; Computational Biology Program, Ontario Institute for Cancer Research, 661 University Avenue Suite 510, Toronto, ON M5G 0A3, Canada.<br /><searchLink fieldCode="AU" term="%22Ruan+L%22">Ruan L</searchLink>; Computational Biology Program, Ontario Institute for Cancer Research, 661 University Avenue Suite 510, Toronto, ON M5G 0A3, Canada.<br /><searchLink fieldCode="AU" term="%22Krassowski+M%22">Krassowski M</searchLink>; Computational Biology Program, Ontario Institute for Cancer Research, 661 University Avenue Suite 510, Toronto, ON M5G 0A3, Canada.<br /><searchLink fieldCode="AU" term="%22Dzneladze+I%22">Dzneladze I</searchLink>; Computational Biology Program, Ontario Institute for Cancer Research, 661 University Avenue Suite 510, Toronto, ON M5G 0A3, Canada.<br /><searchLink fieldCode="AU" term="%22Simpson+JT%22">Simpson JT</searchLink>; Computational Biology Program, Ontario Institute for Cancer Research, 661 University Avenue Suite 510, Toronto, ON M5G 0A3, Canada; Department of Computer Science, University of Toronto, 214 College Street, Toronto, ON M5T 3A1, Canada.<br /><searchLink fieldCode="AU" term="%22Lupien+M%22">Lupien M</searchLink>; Department of Medical Biophysics, University of Toronto, 101 College Street Suite 15-701, Toronto, ON M5G 1L7, Canada; Princess Margaret Cancer Centre, 101 College Street, Toronto, ON M5G 0A3, Canada.<br /><searchLink fieldCode="AU" term="%22Stein+LD%22">Stein LD</searchLink>; Computational Biology Program, Ontario Institute for Cancer Research, 661 University Avenue Suite 510, Toronto, ON M5G 0A3, Canada; Department of Molecular Genetics, University of Toronto, 1 King's College Circle, Toronto, ON M5S 1A8, Canada.<br /><searchLink fieldCode="AU" term="%22Boutros+PC%22">Boutros PC</searchLink>; Department of Medical Biophysics, University of Toronto, 101 College Street Suite 15-701, Toronto, ON M5G 1L7, Canada; Department of Human Genetics, University of California Los Angeles, 10833 Le Conte Avenue, Los Angeles, CA 90095, USA; Department of Urology, University of California Los Angeles, 200 Medical Plaza Driveway #140, Los Angeles, CA 90024, USA; Institute of Precision Health, University of California Los Angeles, 10833 Le Conte Avenue, Los Angeles, CA 90024, USA; Jonsson Comprehensive Cancer Centre, University of California Los Angeles, 10833 Le Conte Avenue, Los Angeles, CA 90024, USA.<br /><searchLink fieldCode="AU" term="%22Wilson+MD%22">Wilson MD</searchLink>; Program in Genetics and Genome Biology, SickKids Research Institute, Peter Gilgan Centre for Research and Learning (PGCRL), 686 Bay Street, Toronto, ON M5G 0A4, Canada; Department of Molecular Genetics, University of Toronto, 1 King's College Circle, Toronto, ON M5S 1A8, Canada.<br /><searchLink fieldCode="AU" term="%22Reimand+J%22">Reimand J</searchLink>; Computational Biology Program, Ontario Institute for Cancer Research, 661 University Avenue Suite 510, Toronto, ON M5G 0A3, Canada; Department of Medical Biophysics, University of Toronto, 101 College Street Suite 15-701, Toronto, ON M5G 1L7, Canada. Electronic address: juri.reimand@utoronto.ca.
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