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Development of a Novel Cell-Permeable Protein-Protein Interaction Inhibitor for the Polo-box Domain of Polo-like Kinase 1.

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Title: Development of a Novel Cell-Permeable Protein-Protein Interaction Inhibitor for the Polo-box Domain of Polo-like Kinase 1.
Authors: Huggins DJ; Medical Research Council Cancer Cell Unit, Hutchison/MRC Research Centre, University of Cambridge, Hills Road, Cambridge CB2 2XZ, United Kingdom.; TCM Group, Cavendish Laboratory, University of Cambridge, 19 JJ Thomson Avenue, Cambridge CB3 0HE, United Kingdom.; Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, United Kingdom., Hardwick BS; Medical Research Council Cancer Cell Unit, Hutchison/MRC Research Centre, University of Cambridge, Hills Road, Cambridge CB2 2XZ, United Kingdom., Sharma P; Medical Research Council Cancer Cell Unit, Hutchison/MRC Research Centre, University of Cambridge, Hills Road, Cambridge CB2 2XZ, United Kingdom., Emery A; Medical Research Council Cancer Cell Unit, Hutchison/MRC Research Centre, University of Cambridge, Hills Road, Cambridge CB2 2XZ, United Kingdom., Laraia L; Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, United Kingdom., Zhang F; Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, United Kingdom., Narvaez AJ; Medical Research Council Cancer Cell Unit, Hutchison/MRC Research Centre, University of Cambridge, Hills Road, Cambridge CB2 2XZ, United Kingdom., Roberts-Thomson M; Medical Research Council Cancer Cell Unit, Hutchison/MRC Research Centre, University of Cambridge, Hills Road, Cambridge CB2 2XZ, United Kingdom., Crooks AT; Medical Research Council Cancer Cell Unit, Hutchison/MRC Research Centre, University of Cambridge, Hills Road, Cambridge CB2 2XZ, United Kingdom., Boyle RG; Sentinel Oncology Ltd., Cambridge Science Park, Milton Road, Cambridge CB4 0EY, United Kingdom., Boyce R; Sentinel Oncology Ltd., Cambridge Science Park, Milton Road, Cambridge CB4 0EY, United Kingdom., Walker DW; Sentinel Oncology Ltd., Cambridge Science Park, Milton Road, Cambridge CB4 0EY, United Kingdom., Mateu N; Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, United Kingdom., McKenzie GJ; Medical Research Council Cancer Cell Unit, Hutchison/MRC Research Centre, University of Cambridge, Hills Road, Cambridge CB2 2XZ, United Kingdom., Spring DR; Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, United Kingdom., Venkitaraman AR; Medical Research Council Cancer Cell Unit, Hutchison/MRC Research Centre, University of Cambridge, Hills Road, Cambridge CB2 2XZ, United Kingdom.
Source: ACS omega [ACS Omega] 2019 Dec 24; Vol. 5 (1), pp. 822-831. Date of Electronic Publication: 2019 Dec 24 (Print Publication: 2020).
Publication Type: Journal Article
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101691658 Publication Model: eCollection Cited Medium: Internet ISSN: 2470-1343 (Electronic) Linking ISSN: 24701343 NLM ISO Abbreviation: ACS Omega Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Development of a Novel Cell-Permeable Protein-Protein Interaction Inhibitor for the Polo-box Domain of Polo-like Kinase 1.
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  Data: <searchLink fieldCode="AU" term="%22Huggins+DJ%22">Huggins DJ</searchLink>; Medical Research Council Cancer Cell Unit, Hutchison/MRC Research Centre, University of Cambridge, Hills Road, Cambridge CB2 2XZ, United Kingdom.; TCM Group, Cavendish Laboratory, University of Cambridge, 19 JJ Thomson Avenue, Cambridge CB3 0HE, United Kingdom.; Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Hardwick+BS%22">Hardwick BS</searchLink>; Medical Research Council Cancer Cell Unit, Hutchison/MRC Research Centre, University of Cambridge, Hills Road, Cambridge CB2 2XZ, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Sharma+P%22">Sharma P</searchLink>; Medical Research Council Cancer Cell Unit, Hutchison/MRC Research Centre, University of Cambridge, Hills Road, Cambridge CB2 2XZ, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Emery+A%22">Emery A</searchLink>; Medical Research Council Cancer Cell Unit, Hutchison/MRC Research Centre, University of Cambridge, Hills Road, Cambridge CB2 2XZ, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Laraia+L%22">Laraia L</searchLink>; Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Zhang+F%22">Zhang F</searchLink>; Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Narvaez+AJ%22">Narvaez AJ</searchLink>; Medical Research Council Cancer Cell Unit, Hutchison/MRC Research Centre, University of Cambridge, Hills Road, Cambridge CB2 2XZ, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Roberts-Thomson+M%22">Roberts-Thomson M</searchLink>; Medical Research Council Cancer Cell Unit, Hutchison/MRC Research Centre, University of Cambridge, Hills Road, Cambridge CB2 2XZ, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Crooks+AT%22">Crooks AT</searchLink>; Medical Research Council Cancer Cell Unit, Hutchison/MRC Research Centre, University of Cambridge, Hills Road, Cambridge CB2 2XZ, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Boyle+RG%22">Boyle RG</searchLink>; Sentinel Oncology Ltd., Cambridge Science Park, Milton Road, Cambridge CB4 0EY, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Boyce+R%22">Boyce R</searchLink>; Sentinel Oncology Ltd., Cambridge Science Park, Milton Road, Cambridge CB4 0EY, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Walker+DW%22">Walker DW</searchLink>; Sentinel Oncology Ltd., Cambridge Science Park, Milton Road, Cambridge CB4 0EY, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Mateu+N%22">Mateu N</searchLink>; Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, United Kingdom.<br /><searchLink fieldCode="AU" term="%22McKenzie+GJ%22">McKenzie GJ</searchLink>; Medical Research Council Cancer Cell Unit, Hutchison/MRC Research Centre, University of Cambridge, Hills Road, Cambridge CB2 2XZ, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Spring+DR%22">Spring DR</searchLink>; Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Venkitaraman+AR%22">Venkitaraman AR</searchLink>; Medical Research Council Cancer Cell Unit, Hutchison/MRC Research Centre, University of Cambridge, Hills Road, Cambridge CB2 2XZ, United Kingdom.
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  Data: <searchLink fieldCode="JN" term="%22101691658%22">ACS omega</searchLink> [ACS Omega] 2019 Dec 24; Vol. 5 (1), pp. 822-831. <i>Date of Electronic Publication: </i>2019 Dec 24 (<i>Print Publication: </i>2020).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Chemical+Society%22">American Chemical Society </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101691658 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>2470-1343 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2224701343%22">24701343 </searchLink><i>NLM ISO Abbreviation: </i>ACS Omega <i>Subsets: </i>PubMed not MEDLINE
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        Value: 10.1021/acsomega.9b03626
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