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Overexpression of transcription factor Foxa1 and target genes remediate therapeutic protein production bottlenecks in Chinese hamster ovary cells.

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Title: Overexpression of transcription factor Foxa1 and target genes remediate therapeutic protein production bottlenecks in Chinese hamster ovary cells.
Authors: Berger A; Department of Fundamental Microbiology, Institute of Biotechnology, University of Lausanne, Lausanne, Switzerland.; Present address: Laboratory of Microsystems LMIS4, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland., Le Fourn V; Selexis SA, Geneva, Switzerland., Masternak J; Department of Fundamental Microbiology, Institute of Biotechnology, University of Lausanne, Lausanne, Switzerland., Regamey A; Selexis SA, Geneva, Switzerland., Bodenmann I; Selexis SA, Geneva, Switzerland., Girod PA; Selexis SA, Geneva, Switzerland., Mermod N; Department of Fundamental Microbiology, Institute of Biotechnology, University of Lausanne, Lausanne, Switzerland.
Source: Biotechnology and bioengineering [Biotechnol Bioeng] 2020 Apr; Vol. 117 (4), pp. 1101-1116. Date of Electronic Publication: 2020 Feb 23.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 7502021 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-0290 (Electronic) Linking ISSN: 00063592 NLM ISO Abbreviation: Biotechnol Bioeng Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Overexpression of transcription factor Foxa1 and target genes remediate therapeutic protein production bottlenecks in Chinese hamster ovary cells.
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  Data: <searchLink fieldCode="AU" term="%22Berger+A%22">Berger A</searchLink>; Department of Fundamental Microbiology, Institute of Biotechnology, University of Lausanne, Lausanne, Switzerland.; Present address: Laboratory of Microsystems LMIS4, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland.<br /><searchLink fieldCode="AU" term="%22Le+Fourn+V%22">Le Fourn V</searchLink>; Selexis SA, Geneva, Switzerland.<br /><searchLink fieldCode="AU" term="%22Masternak+J%22">Masternak J</searchLink>; Department of Fundamental Microbiology, Institute of Biotechnology, University of Lausanne, Lausanne, Switzerland.<br /><searchLink fieldCode="AU" term="%22Regamey+A%22">Regamey A</searchLink>; Selexis SA, Geneva, Switzerland.<br /><searchLink fieldCode="AU" term="%22Bodenmann+I%22">Bodenmann I</searchLink>; Selexis SA, Geneva, Switzerland.<br /><searchLink fieldCode="AU" term="%22Girod+PA%22">Girod PA</searchLink>; Selexis SA, Geneva, Switzerland.<br /><searchLink fieldCode="AU" term="%22Mermod+N%22">Mermod N</searchLink>; Department of Fundamental Microbiology, Institute of Biotechnology, University of Lausanne, Lausanne, Switzerland.
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  Data: <searchLink fieldCode="JN" term="%227502021%22">Biotechnology and bioengineering</searchLink> [Biotechnol Bioeng] 2020 Apr; Vol. 117 (4), pp. 1101-1116. <i>Date of Electronic Publication: </i>2020 Feb 23.
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        Value: 10.1002/bit.27274
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